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MIR410 Gene(RNA Gene)

MicroRNA 410

GCID:
GC14P102209
GIFtS:
17
Genes Participants
UDN Logo

Aliases for MIR410 Gene

Subcategory (RNA class) for MIR410 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR410 Gene

  • MicroRNA 410 2 3 5
  • Hsa-Mir-410 3
  • Mir-410 3
  • MIRN410 3

External Ids for MIR410 Gene

ORGUL Members for MIR410 Gene

Previous HGNC Symbols for MIR410 Gene

  • MIRN410

Previous GeneCards Identifiers for MIR410 Gene

  • GC14P100843
  • GC14P100933
  • GC14P101534
  • GC14P101562
  • GC14P101595
  • GC14P101634
  • GC14P101662
  • GC14P101696
  • GC14P101734
  • GC14P101774
  • GC14P101832
  • GC14P101972
  • GC14P102169
  • GC14P101276
  • GC14P101895

Summaries for MIR410 Gene

Entrez Gene Summary for MIR410 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR410 Gene

MIR410 (MicroRNA 410) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR410 Gene

Genomics for MIR410 Gene

Products:

  1. Regulatory Element

Genomic Location for MIR410 Gene

Chromosome:
14
Start:
101,065,891 bp from pter
End:
101,065,998 bp from pter
Size:
108 bases
Orientation:
Plus strand

Genomic View for MIR410 Gene

Genes around MIR410 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR410 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR410 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR410 Gene

No data available for Regulatory Elements for MIR410 Gene

Proteins for MIR410 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR410 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR410 Gene

Domains & Families for MIR410 Gene

Gene Families for MIR410 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR410: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR410 Gene

Function for MIR410 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR410 Gene

Localization for MIR410 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR410 Gene

Pathways & Interactions for MIR410 Gene

SuperPathways for MIR410 Gene

PathCards logoMore details on SuperPathways for MIR410
No Data Available

Interacting Proteins for MIR410 Gene

Gene Ontology (GO) - Biological Process for MIR410 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR410 Gene

Drugs & Compounds for MIR410 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR410 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR410 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR410 Gene

No ASD Table

Relevant External Links for MIR410 Gene

GeneLoc Exon Structure for
MIR410
ECgene alternative splicing isoforms for
MIR410

Expression for MIR410 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MIR410 Gene

mRNA expression in normal human tissues for MIR410 Gene
mRNA expression by GTEx for MIR410 Gene
genes like me logo Genes that share expression patterns with MIR410: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR410 Gene

Orthologs for MIR410 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR410 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia bta-mir-410 36
  • 95 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia cfa-mir-410 36
  • 65 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Mir410 36
  • 94 (a)
 OneToOne
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-410 36
  • 100 (a)
 OneToOne
Species with no ortholog for MIR410:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR410 Gene

ENSEMBL:
Gene Tree for MIR410 (if available)
TreeFam:
Gene Tree for MIR410 (if available)

Paralogs for MIR410 Gene

No data available for Paralogs for MIR410 Gene

Variants for MIR410 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR410 Gene

Variant ID Type Subtype PubMed ID
nsv509551 CNV Insertion 20534489

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR410 Gene

Disorders for MIR410 Gene

Relevant External Links for MIR410

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR410

No disorders were found for MIR410 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR410 Gene

Publications for MIR410 Gene

  1. MicroRNA-410 promotes cell proliferation by targeting BRD7 in non-small cell lung cancer. (PMID: 26149213) Li D. … Yang Q. (FEBS Lett. 2015) 3 67
  2. miR-410 Inhibition Induces RPE Differentiation of Amniotic Epithelial Stem Cells via Overexpression of OTX2 and RPE65. (PMID: 25351180) Choi S.W. … Kang K.S. (Stem Cell Rev 2015) 3
  3. MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer. (PMID: 25646808) Guo R. … Gu C. (IUBMB Life 2015) 3
  4. MicroRNA-410 reduces the expression of vascular endothelial growth factor and inhibits oxygen-induced retinal neovascularization. (PMID: 24777200) Chen N. … Liu S. (PLoS ONE 2014) 3
  5. MicroRNA-410 regulated lipoprotein lipase variant rs13702 is associated with stroke incidence and modulated by diet in the randomized controlled PREDIMED trial. (PMID: 24990426) Corella D. … OrdovA!s J.M. (Am. J. Clin. Nutr. 2014) 3

Products for MIR410 Gene

Sources for MIR410 Gene

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