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Aliases for MIR410 Gene

Subcategory (RNA class) for MIR410 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR410 Gene

  • MicroRNA 410 2 3 5
  • Hsa-Mir-410 3
  • Mir-410 3
  • MIRN410 3

External Ids for MIR410 Gene

ORGUL Members for MIR410 Gene

Previous HGNC Symbols for MIR410 Gene

  • MIRN410

Previous GeneCards Identifiers for MIR410 Gene

  • GC14P100843
  • GC14P100933
  • GC14P101534
  • GC14P101562
  • GC14P101595
  • GC14P101634
  • GC14P101662
  • GC14P101696
  • GC14P101734
  • GC14P101774
  • GC14P101832
  • GC14P101972
  • GC14P102169
  • GC14P101276
  • GC14P101895
  • GC14P102209
  • GC14P102376

Summaries for MIR410 Gene

Entrez Gene Summary for MIR410 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR410 Gene

MIR410 (MicroRNA 410) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR410 Gene

Genomics for MIR410 Gene

Regulatory Elements for MIR410 Gene

Enhancers for MIR410 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F101096 1.1 FANTOM5 ENCODE 11.4 +32.4 32436 3.2 CTCF SUZ12 JUN ZIC2 ZNF335 GLIS2 ZNF366 POLR2A SCRT2 PATZ1 RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR410 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR410 Gene

Chromosome:
14
Start:
101,065,912 bp from pter
End:
101,065,991 bp from pter
Size:
80 bases
Orientation:
Plus strand

Genomic View for MIR410 Gene

Genes around MIR410 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR410 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR410 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR410 Gene

Proteins for MIR410 Gene

Post-translational modifications for MIR410 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR410 Gene

Domains & Families for MIR410 Gene

Gene Families for MIR410 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR410: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR410 Gene

Function for MIR410 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR410 Gene

Localization for MIR410 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR410 Gene

Pathways & Interactions for MIR410 Gene

genes like me logo Genes that share pathways with MIR410: view

Pathways by source for MIR410 Gene

1 BioSystems pathway for MIR410 Gene

Interacting Proteins for MIR410 Gene

Gene Ontology (GO) - Biological Process for MIR410 Gene

None

No data available for SIGNOR curated interactions for MIR410 Gene

Transcripts for MIR410 Gene

mRNA/cDNA for MIR410 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR410 Gene

No ASD Table

Relevant External Links for MIR410 Gene

GeneLoc Exon Structure for
MIR410
ECgene alternative splicing isoforms for
MIR410

Expression for MIR410 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR410 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR410 Gene:

MIR410
genes like me logo Genes that share expression patterns with MIR410: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR410 Gene

Orthologs for MIR410 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR410 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-410 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-410 35
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir410 35
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-410 35
  • 65 (a)
OneToOne
Species where no ortholog for MIR410 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR410 Gene

ENSEMBL:
Gene Tree for MIR410 (if available)
TreeFam:
Gene Tree for MIR410 (if available)

Paralogs for MIR410 Gene

No data available for Paralogs for MIR410 Gene

Variants for MIR410 Gene

Sequence variations from dbSNP and Humsavar for MIR410 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10134352 -- 101,066,415(+) CCGTG(A/T)GCGTG downstream-variant-500B, upstream-variant-2KB
rs10144688 -- 101,065,899(+) TGAGC(C/T)GATGG downstream-variant-500B, upstream-variant-2KB
rs10144831 -- 101,065,880(+) GACGC(A/G)GCAGC downstream-variant-500B, upstream-variant-2KB
rs10145088 -- 101,066,344(+) CCTGC(A/G)CCTGG downstream-variant-500B, upstream-variant-2KB
rs112268641 -- 101,063,994(+) GTGCC(C/T)TTCGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR410 Gene

Variant ID Type Subtype PubMed ID
nsv565860 CNV gain 21841781
nsv565859 CNV gain 21841781
nsv509551 CNV insertion 20534489
nsv1040993 CNV gain 25217958
esv3635521 CNV gain 21293372

Relevant External Links for MIR410 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR410

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR410 Gene

Disorders for MIR410 Gene

Relevant External Links for MIR410

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR410

No disorders were found for MIR410 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR410 Gene

Publications for MIR410 Gene

  1. miR-410 Inhibition Induces RPE Differentiation of Amniotic Epithelial Stem Cells via Overexpression of OTX2 and RPE65. (PMID: 25351180) Choi S.W. … Kang K.S. (Stem Cell Rev 2015) 3 64
  2. MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer. (PMID: 25646808) Guo R. … Gu C. (IUBMB Life 2015) 3 64
  3. Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors. (PMID: 26125663) MA1ssnich P. … D'Angelo D. (Cell Cycle 2015) 3 64
  4. MicroRNA-410 promotes cell proliferation by targeting BRD7 in non-small cell lung cancer. (PMID: 26149213) Li D. … Yang Q. (FEBS Lett. 2015) 3 64
  5. miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus. (PMID: 26307561) Mi Y. … Huang P. (J. Mol. Endocrinol. 2015) 3 64

Products for MIR410 Gene

Sources for MIR410 Gene

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