Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3978 Gene

Subcategory (RNA class) for MIR3978 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3978 Gene

  • MicroRNA 3978 2 3 5
  • Hsa-Mir-3978 3

External Ids for MIR3978 Gene

Previous GeneCards Identifiers for MIR3978 Gene

  • GC0XU901741
  • GC0XP109327

Summaries for MIR3978 Gene

Entrez Gene Summary for MIR3978 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3978 Gene

MIR3978 (MicroRNA 3978) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3978 Gene

Genomics for MIR3978 Gene

Regulatory Elements for MIR3978 Gene

Enhancers for MIR3978 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG110085 1.6 FANTOM5 Ensembl ENCODE 0.4 +5.9 5928 5.1 FOXA2 SIN3A FEZF1 BRCA1 TCF12 ZNF766 GATA2 FOS SREBF1 MAFF TMEM164 MIR3978 LOC101928589
GH0XG110081 0.7 Ensembl ENCODE 0.7 +0.0 37 2.2 GATA2 POLR2A NR3C1 TMEM164 MIR3978 LOC101928589
GH0XG110167 1.1 Ensembl ENCODE 0.2 +86.5 86475 2.0 CTCF ESRRA SIN3A RAD21 FOXM1 HIC1 ZFHX2 CTBP1 GLIS2 EGR1 ACSL4 LOC101928589 MIR3978
GH0XG110122 0.7 ENCODE 0.3 +41.5 41513 1.5 GATAD2A HLF CEBPB CEBPG FEZF1 ZNF366 SMARCA4 HSF1 CEBPA RCOR2 TMEM164 MIR3978 LOC101928589
GH0XG110160 1 Ensembl ENCODE 0.2 +79.0 78991 1.5 CTCF ARNT ZNF2 RAD21 PATZ1 SCRT2 SMC3 NR2F6 SMARCA5 SCRT1 LOC101928589 MIR3978
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3978 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3978 Gene

Chromosome:
X
Start:
110,082,118 bp from pter
End:
110,082,218 bp from pter
Size:
101 bases
Orientation:
Plus strand

Genomic View for MIR3978 Gene

Genes around MIR3978 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3978 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3978 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3978 Gene

Proteins for MIR3978 Gene

Post-translational modifications for MIR3978 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3978 Gene

Domains & Families for MIR3978 Gene

Gene Families for MIR3978 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3978: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3978 Gene

Function for MIR3978 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3978 Gene

Localization for MIR3978 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3978 Gene

Pathways & Interactions for MIR3978 Gene

SuperPathways for MIR3978 Gene

No Data Available

Interacting Proteins for MIR3978 Gene

Gene Ontology (GO) - Biological Process for MIR3978 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3978 Gene

Drugs & Compounds for MIR3978 Gene

No Compound Related Data Available

Transcripts for MIR3978 Gene

mRNA/cDNA for MIR3978 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3978 Gene

No ASD Table

Relevant External Links for MIR3978 Gene

GeneLoc Exon Structure for
MIR3978
ECgene alternative splicing isoforms for
MIR3978

Expression for MIR3978 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3978 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3978 Gene:

MIR3978
genes like me logo Genes that share expression patterns with MIR3978: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3978 Gene

Orthologs for MIR3978 Gene

Evolution for MIR3978 Gene

ENSEMBL:
Gene Tree for MIR3978 (if available)
TreeFam:
Gene Tree for MIR3978 (if available)

No data available for Orthologs for MIR3978 Gene

Paralogs for MIR3978 Gene

No data available for Paralogs for MIR3978 Gene

Variants for MIR3978 Gene

Sequence variations from dbSNP and Humsavar for MIR3978 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1001192437 -- 110,080,232(+) TAGCA(C/T)GAGTT intron-variant, upstream-variant-2KB
rs1002874100 -- 110,082,284(+) TTATC(A/C)TTCCT intron-variant, downstream-variant-500B
rs1003054101 -- 110,081,516(+) GACTG(A/G)ATGTG intron-variant, upstream-variant-2KB
rs1003147556 -- 110,081,892(+) TATGA(C/T)GTGTG intron-variant, upstream-variant-2KB
rs1005882988 -- 110,081,504(+) GAAAG(-/TT)TACAT intron-variant, upstream-variant-2KB

Relevant External Links for MIR3978 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3978

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3978 Gene

Disorders for MIR3978 Gene

Relevant External Links for MIR3978

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3978

No disorders were found for MIR3978 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3978 Gene

Publications for MIR3978 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G. … Link D.C. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3978 Gene

Sources for MIR3978 Gene

Content
Loading form....