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Aliases for MIR3978 Gene

Subcategory (RNA class) for MIR3978 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3978 Gene

  • MicroRNA 3978 2 3 5
  • Hsa-Mir-3978 3

External Ids for MIR3978 Gene

Previous GeneCards Identifiers for MIR3978 Gene

  • GC0XU901741
  • GC0XP109327

Summaries for MIR3978 Gene

Entrez Gene Summary for MIR3978 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3978 Gene

MIR3978 (MicroRNA 3978) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3978 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3978 Gene

Genomics for MIR3978 Gene

GeneHancer (GH) Regulatory Elements for MIR3978 Gene

Promoters and enhancers for MIR3978 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI110081 Enhancer 0.4 Ensembl ENCODE 550.8 +0.0 36 2.2 MIR3978 TMEM164 LOC101928589
GH0XI110085 Enhancer 1.4 FANTOM5 Ensembl ENCODE 0.4 +5.9 5927 5.1 FOXA2 SIN3A FEZF1 BRCA1 TCF12 ZNF766 FOS RUNX3 SREBF1 NFIL3 TMEM164 MIR3978 LOC101928589
GH0XI110171 Enhancer 1 Ensembl ENCODE 0.2 +90.7 90745 2.7 HDGF PKNOX1 NFIB IRF4 ATF7 FOS BCLAF1 IKZF2 RUNX3 GATAD2B LOC101928589 MIR3978 TMEM164
GH0XI110167 Enhancer 1 Ensembl ENCODE 0.2 +86.5 86474 2 NCOA3 CTCF ESRRA SIN3A RAD21 HIC1 FOXM1 ZFHX2 CTBP1 GLIS2 ACSL4 LOC101928589 MIR3978 TMEM164
GH0XI110122 Enhancer 0.6 ENCODE 0.3 +41.5 41513 1.5 GATAD2A HLF CEBPB CEBPG FEZF1 NFIL3 ZNF366 HSF1 RCOR2 CEBPA TMEM164 MIR3978 LOC101928589
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3978 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3978 Gene

Genomic Locations for MIR3978 Gene
chrX:110,082,118-110,082,218
(GRCh38/hg38)
Size:
101 bases
Orientation:
Plus strand
chrX:109,325,346-109,325,446
(GRCh37/hg19)

Genomic View for MIR3978 Gene

Genes around MIR3978 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3978 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3978 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3978 Gene

Proteins for MIR3978 Gene

Post-translational modifications for MIR3978 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3978 Gene

Domains & Families for MIR3978 Gene

Gene Families for MIR3978 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3978: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3978 Gene

Function for MIR3978 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3978 Gene

Localization for MIR3978 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3978 Gene

Pathways & Interactions for MIR3978 Gene

SuperPathways for MIR3978 Gene

No Data Available

Interacting Proteins for MIR3978 Gene

Gene Ontology (GO) - Biological Process for MIR3978 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3978 Gene

Drugs & Compounds for MIR3978 Gene

No Compound Related Data Available

Transcripts for MIR3978 Gene

mRNA/cDNA for MIR3978 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3978 Gene

No ASD Table

Relevant External Links for MIR3978 Gene

GeneLoc Exon Structure for
MIR3978
ECgene alternative splicing isoforms for
MIR3978

Expression for MIR3978 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3978 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3978 Gene:

MIR3978
genes like me logo Genes that share expression patterns with MIR3978: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3978 Gene

Orthologs for MIR3978 Gene

Evolution for MIR3978 Gene

ENSEMBL:
Gene Tree for MIR3978 (if available)
TreeFam:
Gene Tree for MIR3978 (if available)

No data available for Orthologs for MIR3978 Gene

Paralogs for MIR3978 Gene

No data available for Paralogs for MIR3978 Gene

Variants for MIR3978 Gene

Sequence variations from dbSNP and Humsavar for MIR3978 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1001192437 -- 110,080,232(+) C/T upstream_transcript_variant
rs1002874100 -- 110,082,284(+) C/A downstream_transcript_variant
rs1003054101 -- 110,081,516(+) G/A upstream_transcript_variant
rs1003147556 -- 110,081,892(+) C/T upstream_transcript_variant
rs1005882988 -- 110,081,504(+) TTT/T upstream_transcript_variant

Additional Variant Information for MIR3978 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3978

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3978 Gene

Disorders for MIR3978 Gene

Additional Disease Information for MIR3978

No disorders were found for MIR3978 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3978 Gene

Publications for MIR3978 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G … Link DC (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. MiRNA-3978 regulates peritoneal gastric cancer metastasis by targeting legumain. (PMID: 27793040) Zhang Y … Fang XD (Oncotarget 2016) 3

Products for MIR3978 Gene

Sources for MIR3978 Gene

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