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Aliases for MIR3977 Gene

Subcategory (RNA class) for MIR3977 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3977 Gene

  • MicroRNA 3977 2 3 5
  • Hsa-Mir-3977 3

External Ids for MIR3977 Gene

Previous GeneCards Identifiers for MIR3977 Gene

  • GC05U901569
  • GC05P082137

Summaries for MIR3977 Gene

Entrez Gene Summary for MIR3977 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3977 Gene

MIR3977 (MicroRNA 3977) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3977 Gene

Genomics for MIR3977 Gene

Regulatory Elements for MIR3977 Gene

Enhancers for MIR3977 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F082858 0.5 FANTOM5 ENCODE 0.3 +18.5 18527 1.0 LINC01338 MIR3977
GH05F082856 0.5 ENCODE 0.3 +16.4 16385 1.1 CEBPG ZNF843 ZNF558 LINC01338 MIR3977
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3977 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3977 Gene

Chromosome:
5
Start:
82,840,155 bp from pter
End:
82,840,224 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR3977 Gene

Genes around MIR3977 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3977 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3977 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3977 Gene

Proteins for MIR3977 Gene

Post-translational modifications for MIR3977 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3977 Gene

Domains & Families for MIR3977 Gene

Gene Families for MIR3977 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3977: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3977 Gene

Function for MIR3977 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3977 Gene

Localization for MIR3977 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3977 Gene

Pathways & Interactions for MIR3977 Gene

SuperPathways for MIR3977 Gene

No Data Available

Interacting Proteins for MIR3977 Gene

Gene Ontology (GO) - Biological Process for MIR3977 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3977 Gene

Transcripts for MIR3977 Gene

mRNA/cDNA for MIR3977 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3977 Gene

No ASD Table

Relevant External Links for MIR3977 Gene

GeneLoc Exon Structure for
MIR3977
ECgene alternative splicing isoforms for
MIR3977

Expression for MIR3977 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3977 Gene:

MIR3977
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3977 Gene

Orthologs for MIR3977 Gene

Evolution for MIR3977 Gene

ENSEMBL:
Gene Tree for MIR3977 (if available)
TreeFam:
Gene Tree for MIR3977 (if available)

No data available for Orthologs for MIR3977 Gene

Paralogs for MIR3977 Gene

No data available for Paralogs for MIR3977 Gene

Variants for MIR3977 Gene

Sequence variations from dbSNP and Humsavar for MIR3977 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10073948 -- 82,838,801(+) AAGGA(C/T)GCTGA upstream-variant-2KB
rs10462387 -- 82,839,160(+) AACTC(A/G)GGGAA upstream-variant-2KB
rs113309601 -- 82,840,245(+) CTTCT(-/TCTTC)TTCTT downstream-variant-500B
rs11377178 -- 82,840,009(+) AAAAA(-/A/AT)TCAAA upstream-variant-2KB
rs115565573 -- 82,840,408(+) TGAGA(A/G)TGAAG downstream-variant-500B

Relevant External Links for MIR3977 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3977

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3977 Gene

Disorders for MIR3977 Gene

Relevant External Links for MIR3977

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3977

No disorders were found for MIR3977 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3977 Gene

Publications for MIR3977 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G. … Link D.C. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3977 Gene

Sources for MIR3977 Gene

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