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Aliases for MIR3975 Gene

Subcategory (RNA class) for MIR3975 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3975 Gene

  • MicroRNA 3975 2 3 5
  • Hsa-Mir-3975 3

External Ids for MIR3975 Gene

Previous GeneCards Identifiers for MIR3975 Gene

  • GC18U900663
  • GC18P033173

Summaries for MIR3975 Gene

Entrez Gene Summary for MIR3975 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3975 Gene

MIR3975 (MicroRNA 3975) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3975 Gene

Genomics for MIR3975 Gene

Regulatory Elements for MIR3975 Gene

Enhancers for MIR3975 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18F035591 1 Ensembl ENCODE 0.8 +0.8 764 3.0 HDGF MTA2 CEBPB JUNB TBX21 RARA CBX5 TARDBP EED IKZF1 ENSG00000266965 MIR3975
GH18F035589 0.7 Ensembl ENCODE 0.8 -2.5 -2488 0.3 CTCF RAD21 MAFK GALNT1 MIR3975
GH18F035580 1 ENCODE 0.4 -9.4 -9388 3.6 PKNOX1 SIN3A FEZF1 ZNF48 ZNF2 GLIS2 ZNF143 ZNF207 ZNF263 TSHZ1 GALNT1 MIR3975
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3975 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3975 Gene

Chromosome:
18
Start:
35,591,737 bp from pter
End:
35,591,806 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR3975 Gene

Genes around MIR3975 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3975 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3975 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3975 Gene

Proteins for MIR3975 Gene

Post-translational modifications for MIR3975 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3975 Gene

Domains & Families for MIR3975 Gene

Gene Families for MIR3975 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3975: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3975 Gene

Function for MIR3975 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3975 Gene

Localization for MIR3975 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3975 Gene

Pathways & Interactions for MIR3975 Gene

SuperPathways for MIR3975 Gene

No Data Available

Interacting Proteins for MIR3975 Gene

Gene Ontology (GO) - Biological Process for MIR3975 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3975 Gene

Transcripts for MIR3975 Gene

mRNA/cDNA for MIR3975 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3975 Gene

No ASD Table

Relevant External Links for MIR3975 Gene

GeneLoc Exon Structure for
MIR3975
ECgene alternative splicing isoforms for
MIR3975

Expression for MIR3975 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3975 Gene:

MIR3975
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3975 Gene

Orthologs for MIR3975 Gene

Evolution for MIR3975 Gene

ENSEMBL:
Gene Tree for MIR3975 (if available)
TreeFam:
Gene Tree for MIR3975 (if available)

No data available for Orthologs for MIR3975 Gene

Paralogs for MIR3975 Gene

No data available for Paralogs for MIR3975 Gene

Variants for MIR3975 Gene

Sequence variations from dbSNP and Humsavar for MIR3975 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs113101919 -- 35,591,848(+) AATGG(A/G)ATCAG intron-variant, downstream-variant-500B
rs114801015 -- 35,591,654(+) ATGGA(A/T)GTTCT intron-variant, upstream-variant-2KB
rs118180800 -- 35,591,097(+) GAAAA(A/G)GGTGG intron-variant, upstream-variant-2KB
rs12955669 -- 35,589,777(+) gtttg(G/T)aacat intron-variant, upstream-variant-2KB
rs12960283 -- 35,592,165(+) GTTAC(A/G)GGCCC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3975 Gene

Variant ID Type Subtype PubMed ID
nsv1065113 CNV loss 25217958

Relevant External Links for MIR3975 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3975

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3975 Gene

Disorders for MIR3975 Gene

Relevant External Links for MIR3975

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3975

No disorders were found for MIR3975 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3975 Gene

Publications for MIR3975 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G. … Link D.C. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3975 Gene

Sources for MIR3975 Gene

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