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Aliases for MIR3975 Gene

Subcategory (RNA class) for MIR3975 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR3975 Gene

  • MicroRNA 3975 2 3
  • Hsa-Mir-3975 3

External Ids for MIR3975 Gene

Previous GeneCards Identifiers for MIR3975 Gene

  • GC18U900663
  • GC18P033173

Summaries for MIR3975 Gene

Entrez Gene Summary for MIR3975 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3975 Gene

MIR3975 (MicroRNA 3975) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3975 Gene

Genomics for MIR3975 Gene

Genomic Location for MIR3975 Gene

Chromosome:
18
Start:
35,591,737 bp from pter
End:
35,591,806 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR3975 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR3975 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3975 Gene

No data available for Regulatory Elements for MIR3975 Gene

Proteins for MIR3975 Gene

Post-translational modifications for MIR3975 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3975 Gene

Domains & Families for MIR3975 Gene

Gene Families for MIR3975 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3975: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3975 Gene

Function for MIR3975 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3975 Gene

Localization for MIR3975 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3975 Gene

Pathways & Interactions for MIR3975 Gene

SuperPathways for MIR3975 Gene

No Data Available

Interacting Proteins for MIR3975 Gene

Gene Ontology (GO) - Biological Process for MIR3975 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3975 Gene

Drugs & Compounds for MIR3975 Gene

No Compound Related Data Available

Transcripts for MIR3975 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3975 Gene

No ASD Table

Relevant External Links for MIR3975 Gene

GeneLoc Exon Structure for
MIR3975
ECgene alternative splicing isoforms for
MIR3975

No data available for mRNA/cDNA for MIR3975 Gene

Expression for MIR3975 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR3975 Gene

Orthologs for MIR3975 Gene

No data available for Orthologs and Evolution for MIR3975 Gene

Paralogs for MIR3975 Gene

No data available for Paralogs for MIR3975 Gene

Variants for MIR3975 Gene

Sequence variations from dbSNP and Humsavar for MIR3975 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs12955669 -- 35,589,777(+) gtttg(G/T)aacat upstream-variant-2KB
rs12960283 -- 35,592,165(+) GTTAC(A/G)GGCCC downstream-variant-500B
rs35019400 -- 35,590,458(+) TATGG(-/G)AACCA upstream-variant-2KB
rs35196719 -- 35,591,060(+) CTGAA(-/C)ACCTG upstream-variant-2KB
rs56159914 -- 35,592,011(+) AGGTG(A/G)AACTG downstream-variant-500B

Relevant External Links for MIR3975 Gene

HapMap Linkage Disequilibrium report
MIR3975

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3975 Gene

Disorders for MIR3975 Gene

Relevant External Links for MIR3975

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3975
genes like me logo Genes that share disorders with MIR3975: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3975 Gene

Publications for MIR3975 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G. … Link D.C. (Blood 2010) 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR3975 Gene

Sources for MIR3975 Gene

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