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Aliases for MIR3973 Gene

Subcategory (RNA class) for MIR3973 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3973 Gene

  • MicroRNA 3973 2 3 5
  • Hsa-Mir-3973 3

External Ids for MIR3973 Gene

Previous GeneCards Identifiers for MIR3973 Gene

  • GC11U901866

Summaries for MIR3973 Gene

Entrez Gene Summary for MIR3973 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3973 Gene

MIR3973 (MicroRNA 3973) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3973 Gene

Genomics for MIR3973 Gene

Regulatory Elements for MIR3973 Gene

Enhancers for MIR3973 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G036008 1.3 Ensembl ENCODE dbSUPER 0.7 -0.9 -921 3.3 CTCF JUN CEBPG RAD21 RFX5 CTBP1 GATA3 FOS MAFK MAFG LDLRAD3 CD44 MIR3973 RPL12P31
GH11G036011 1 Ensembl ENCODE 0.7 +2.5 2483 1.3 BCOR RING1 CTCF TSC22D4 RBBP5 FOSL1 GATA3 GATA2 ADNP FOS LDLRAD3 COMMD9 MIR3973 GC11M036020
GH11G036030 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +21.0 21011 1.8 PKNOX1 MTA2 FEZF1 ARID1B PRDM6 ATF3 IKZF1 ADNP PBX2 HMBOX1 GC11M036020 MIR3973
GH11G036014 1.1 Ensembl ENCODE dbSUPER 0.4 +5.5 5514 2.2 ZFHX2 ATF3 PBX2 CEBPB SIN3A MAX MNT EGR2 LDLRAD3 MIR3973 GC11M036020
GH11G036007 0.6 ENCODE 0.7 -2.6 -2590 0.0 ZNF217 CTBP1 GATA3 FOS DPF2 SP7 LDLRAD3 MIR3973 RPL12P31
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3973 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3973 Gene

Chromosome:
11
Start:
36,010,098 bp from pter
End:
36,010,204 bp from pter
Size:
107 bases
Orientation:
Plus strand

Genomic View for MIR3973 Gene

Genes around MIR3973 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3973 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3973 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3973 Gene

Proteins for MIR3973 Gene

Post-translational modifications for MIR3973 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3973 Gene

Domains & Families for MIR3973 Gene

Gene Families for MIR3973 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3973: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3973 Gene

Function for MIR3973 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3973 Gene

Localization for MIR3973 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3973 Gene

Pathways & Interactions for MIR3973 Gene

SuperPathways for MIR3973 Gene

No Data Available

Interacting Proteins for MIR3973 Gene

Gene Ontology (GO) - Biological Process for MIR3973 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3973 Gene

Drugs & Compounds for MIR3973 Gene

No Compound Related Data Available

Transcripts for MIR3973 Gene

mRNA/cDNA for MIR3973 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3973 Gene

No ASD Table

Relevant External Links for MIR3973 Gene

GeneLoc Exon Structure for
MIR3973
ECgene alternative splicing isoforms for
MIR3973

Expression for MIR3973 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3973 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3973 Gene:

MIR3973
genes like me logo Genes that share expression patterns with MIR3973: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3973 Gene

Orthologs for MIR3973 Gene

Evolution for MIR3973 Gene

ENSEMBL:
Gene Tree for MIR3973 (if available)
TreeFam:
Gene Tree for MIR3973 (if available)

No data available for Orthologs for MIR3973 Gene

Paralogs for MIR3973 Gene

No data available for Paralogs for MIR3973 Gene

Variants for MIR3973 Gene

Sequence variations from dbSNP and Humsavar for MIR3973 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000700237 -- 36,009,537(+) GAAAG(A/G)TGTAA intron-variant, upstream-variant-2KB
rs1001218998 -- 36,009,765(+) TATTC(A/G)TATTA intron-variant, upstream-variant-2KB
rs1002082108 -- 36,008,840(+) CCAGC(C/T)TGGAT intron-variant, upstream-variant-2KB
rs1002483245 -- 36,009,123(+) GTATC(C/T)AGTGA intron-variant, upstream-variant-2KB
rs1002628126 -- 36,008,878(+) AAAAA(C/T)ATGTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3973 Gene

Variant ID Type Subtype PubMed ID
esv2422305 CNV duplication 17116639
nsv1042014 CNV loss 25217958
nsv554002 CNV loss 21841781
nsv7735 CNV insertion 18451855
nsv832122 CNV gain 17160897

Relevant External Links for MIR3973 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3973

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3973 Gene

Disorders for MIR3973 Gene

Relevant External Links for MIR3973

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3973

No disorders were found for MIR3973 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3973 Gene

Publications for MIR3973 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G. … Link D.C. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3973 Gene

Sources for MIR3973 Gene

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