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Aliases for MIR3960 Gene

Subcategory (RNA class) for MIR3960 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3960 Gene

  • MicroRNA 3960 2 3 5
  • Hsa-Mir-3960 3

External Ids for MIR3960 Gene

Previous GeneCards Identifiers for MIR3960 Gene

  • GC09U901725
  • GC09P130553
  • GC09P130554
  • GC09P130557

Summaries for MIR3960 Gene

Entrez Gene Summary for MIR3960 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3960 Gene

MIR3960 (MicroRNA 3960) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are HIV Life Cycle and Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3960 Gene

Genomics for MIR3960 Gene

Regulatory Elements for MIR3960 Gene


Promoters for MIR3960 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000337888 167 2401 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for MIR3960 Gene

Chromosome:
9
Start:
127,785,833 bp from pter
End:
127,785,923 bp from pter
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR3960 Gene

Genes around MIR3960 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3960 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3960 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3960 Gene

Proteins for MIR3960 Gene

Post-translational modifications for MIR3960 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3960 Gene

Domains & Families for MIR3960 Gene

Gene Families for MIR3960 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3960: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3960 Gene

Function for MIR3960 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3960 Gene

Localization for MIR3960 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3960 Gene

Pathways & Interactions for MIR3960 Gene

genes like me logo Genes that share pathways with MIR3960: view

Interacting Proteins for MIR3960 Gene

Gene Ontology (GO) - Biological Process for MIR3960 Gene

None

No data available for SIGNOR curated interactions for MIR3960 Gene

Transcripts for MIR3960 Gene

mRNA/cDNA for MIR3960 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3960 Gene

No ASD Table

Relevant External Links for MIR3960 Gene

GeneLoc Exon Structure for
MIR3960
ECgene alternative splicing isoforms for
MIR3960

Expression for MIR3960 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3960 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3960 Gene:

MIR3960
genes like me logo Genes that share expression patterns with MIR3960: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3960 Gene

Orthologs for MIR3960 Gene

Evolution for MIR3960 Gene

ENSEMBL:
Gene Tree for MIR3960 (if available)
TreeFam:
Gene Tree for MIR3960 (if available)

No data available for Orthologs for MIR3960 Gene

Paralogs for MIR3960 Gene

No data available for Paralogs for MIR3960 Gene

Variants for MIR3960 Gene

Sequence variations from dbSNP and Humsavar for MIR3960 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs794728003 other 127,785,950(+) GGCCT(C/G)TCGGG nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs1000622607 -- 127,784,616(+) GGAGG(G/T)GGAAT intron-variant, upstream-variant-2KB
rs1000911478 -- 127,784,670(+) CGCGA(G/T)GGGGG intron-variant, upstream-variant-2KB
rs1000925389 -- 127,784,697(+) TGAAC(C/G)GTGAG intron-variant, upstream-variant-2KB
rs1002805270 -- 127,785,314(+) GTGGG(A/G)GTAAA downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3960 Gene

Variant ID Type Subtype PubMed ID
dgv12879n54 CNV loss 21841781
esv3891727 CNV gain 25118596
nsv1075676 CNV deletion 25765185
nsv466573 CNV loss 19166990
nsv466575 CNV loss 19166990
nsv471323 CNV loss 18288195
nsv615371 CNV loss 21841781
nsv615373 CNV loss 21841781
nsv615374 CNV loss 21841781
nsv825094 CNV gain 20364138

Relevant External Links for MIR3960 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3960

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3960 Gene

Disorders for MIR3960 Gene

Relevant External Links for MIR3960

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3960

No disorders were found for MIR3960 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3960 Gene

Publications for MIR3960 Gene

  1. A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation. (PMID: 21324897) Hu R. … Luo X.H. (J. Biol. Chem. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3960 Gene

Sources for MIR3960 Gene

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