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Aliases for MIR3945 Gene

Subcategory (RNA class) for MIR3945 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3945 Gene

  • MicroRNA 3945 2 3 5
  • Hsa-Mir-3945 3

External Ids for MIR3945 Gene

Previous GeneCards Identifiers for MIR3945 Gene

  • GC04U901413
  • GC04M185774

Summaries for MIR3945 Gene

Entrez Gene Summary for MIR3945 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3945 Gene

MIR3945 (MicroRNA 3945) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3945 Gene

Genomics for MIR3945 Gene

Regulatory Elements for MIR3945 Gene

Enhancers for MIR3945 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G184854 1.6 FANTOM5 Ensembl ENCODE 0.7 -4.4 -4438 2.6 HDGF PKNOX1 ATF1 ARNT YY1 TCF12 FOS NCOA1 JUNB TBX21 ACSL1 CENPU IRF2 MIR3945HG MIR3945
GH04G184848 1.4 FANTOM5 Ensembl ENCODE 0.7 +2.1 2129 1.3 CTCF RELA RFX5 ARID3A EED ZNF26 ETV6 RELB IKZF2 CREM ACSL1 PRIMPOL CFAP97 IRF2 MIR3945
GH04G184849 1.2 Ensembl ENCODE 0.7 -0.9 -863 4.1 HDGF FOXA2 ARID4B DMAP1 ZNF48 YY1 ZNF143 FOS CEBPZ NFYC PRIMPOL UFSP2 CFAP97 MIR3945 MIR3945HG
GH04G184844 1 ENCODE 0.4 +6.5 6512 0.6 HDGF PKNOX1 ATF1 CREB3L1 ARNT TCF12 ZNF766 CBX5 ELK1 GATA2 MIR3945 ACSL1
GH04G184838 0.9 ENCODE 0.4 +12.1 12119 0.1 FOXA2 ATF1 RARA ZNF366 CREM THAP11 SP3 ZNF362 SP5 ZHX2 ACSL1 MIR3945
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3945 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3945 Gene

Chromosome:
4
Start:
184,851,013 bp from pter
End:
184,851,110 bp from pter
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR3945 Gene

Genes around MIR3945 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3945 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3945 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3945 Gene

Proteins for MIR3945 Gene

Post-translational modifications for MIR3945 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3945 Gene

Domains & Families for MIR3945 Gene

Gene Families for MIR3945 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3945: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3945 Gene

Function for MIR3945 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3945 Gene

Localization for MIR3945 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3945 Gene

Pathways & Interactions for MIR3945 Gene

SuperPathways for MIR3945 Gene

No Data Available

Interacting Proteins for MIR3945 Gene

Gene Ontology (GO) - Biological Process for MIR3945 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3945 Gene

Drugs & Compounds for MIR3945 Gene

No Compound Related Data Available

Transcripts for MIR3945 Gene

mRNA/cDNA for MIR3945 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3945 Gene

No ASD Table

Relevant External Links for MIR3945 Gene

GeneLoc Exon Structure for
MIR3945
ECgene alternative splicing isoforms for
MIR3945

Expression for MIR3945 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3945 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3945 Gene:

MIR3945
genes like me logo Genes that share expression patterns with MIR3945: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3945 Gene

Orthologs for MIR3945 Gene

Evolution for MIR3945 Gene

ENSEMBL:
Gene Tree for MIR3945 (if available)
TreeFam:
Gene Tree for MIR3945 (if available)

No data available for Orthologs for MIR3945 Gene

Paralogs for MIR3945 Gene

No data available for Paralogs for MIR3945 Gene

Variants for MIR3945 Gene

Sequence variations from dbSNP and Humsavar for MIR3945 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1003389151 -- 184,851,229(+) CTAGT(C/T)ACCAA intron-variant, upstream-variant-2KB
rs1003402478 -- 184,851,823(+) ATTTA(C/T)ACAAC intron-variant, upstream-variant-2KB
rs1003475149 -- 184,852,166(+) ATGAT(A/G)GAAGA intron-variant, upstream-variant-2KB
rs1004048345 -- 184,851,614(+) GATCA(A/C)AATCA intron-variant, upstream-variant-2KB
rs1004483363 -- 184,852,492(+) TAACC(C/T)GCACC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3945 Gene

Variant ID Type Subtype PubMed ID
dgv1552e212 CNV loss 25503493
esv3569858 CNV loss 25503493
nsv950585 CNV duplication 24416366

Relevant External Links for MIR3945 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3945

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3945 Gene

Disorders for MIR3945 Gene

Relevant External Links for MIR3945

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3945

No disorders were found for MIR3945 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3945 Gene

Publications for MIR3945 Gene

  1. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. (PMID: 20498841) Liao J.Y. … Qu L.H. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3945 Gene

Sources for MIR3945 Gene

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