Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3944 Gene

Subcategory (RNA class) for MIR3944 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3944 Gene

  • MicroRNA 3944 2 3 5
  • Hsa-Mir-3944 3

External Ids for MIR3944 Gene

Previous GeneCards Identifiers for MIR3944 Gene

  • GC10U901441
  • GC10M135188

Summaries for MIR3944 Gene

Entrez Gene Summary for MIR3944 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3944 Gene

MIR3944 (MicroRNA 3944) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3944 Gene

Genomics for MIR3944 Gene

Regulatory Elements for MIR3944 Gene

Enhancers for MIR3944 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F133361 0.7 Ensembl ENCODE 0.4 +9.8 9765 0.9 PAF1 KLF1 SP3 ZBTB8A ZFHX2 POLR2A IKZF1 NBN EGR2 TUBGCP2 ZNF511 ENSG00000235245 ECHS1 OR7M1P GC10P133359 MIR3944
GH10F133364 0.5 ENCODE 0.4 +6.6 6627 0.6 ZNF687 GC10P133359 MIR3944
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3944 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3944 Gene

Chromosome:
10
Start:
133,371,556 bp from pter
End:
133,371,663 bp from pter
Size:
108 bases
Orientation:
Minus strand

Genomic View for MIR3944 Gene

Genes around MIR3944 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3944 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3944 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3944 Gene

ORGUL Member Location for MIR3944 Gene

ORGUL Member Location for MIR3944 gene

Proteins for MIR3944 Gene

Post-translational modifications for MIR3944 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3944 Gene

Domains & Families for MIR3944 Gene

Gene Families for MIR3944 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3944: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3944 Gene

Function for MIR3944 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3944 Gene

Localization for MIR3944 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3944 Gene

Pathways & Interactions for MIR3944 Gene

SuperPathways for MIR3944 Gene

No Data Available

Interacting Proteins for MIR3944 Gene

Gene Ontology (GO) - Biological Process for MIR3944 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3944 Gene

Transcripts for MIR3944 Gene

mRNA/cDNA for MIR3944 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3944 Gene

No ASD Table

Relevant External Links for MIR3944 Gene

GeneLoc Exon Structure for
MIR3944
ECgene alternative splicing isoforms for
MIR3944

Expression for MIR3944 Gene

mRNA expression in normal human tissues for MIR3944 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3944 Gene:

MIR3944
genes like me logo Genes that share expression patterns with MIR3944: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3944 Gene

Orthologs for MIR3944 Gene

Evolution for MIR3944 Gene

ENSEMBL:
Gene Tree for MIR3944 (if available)
TreeFam:
Gene Tree for MIR3944 (if available)

No data available for Orthologs for MIR3944 Gene

Paralogs for MIR3944 Gene

No data available for Paralogs for MIR3944 Gene

Variants for MIR3944 Gene

Sequence variations from dbSNP and Humsavar for MIR3944 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs587776497 Pathogenic 133,373,332(-) AGCCA(G/T)GGCCG upstream-variant-2KB, reference, missense
rs587776498 Pathogenic 133,373,329(-) CATGG(C/T)CGCCC upstream-variant-2KB, reference, missense
rs10466126 -- 133,373,302(+) CGCGG(A/G)CGCAG upstream-variant-2KB, reference, missense
rs11101717 -- 133,372,413(+) AGGAG(A/G)TGTCA intron-variant, upstream-variant-2KB
rs111761923 -- 133,373,495(+) CCCAG(A/G)CCCGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3944 Gene

Variant ID Type Subtype PubMed ID
dgv2e196 CNV duplication 17116639
dgv35e55 CNV gain 17911159
dgv3e196 CNV duplication 17116639
esv2750853 CNV gain 17911159
esv2759793 CNV gain+loss 17122850
esv3625030 CNV gain 21293372
esv3625043 CNV gain 21293372
nsv1037772 CNV gain 25217958
nsv1052904 CNV gain 25217958
nsv428243 CNV gain 18775914
nsv467509 CNV loss 19166990
nsv470980 CNV loss 18288195
nsv470981 CNV gain 18288195
nsv527785 CNV loss 19592680
nsv528260 CNV loss 19592680
nsv552589 CNV gain 21841781
nsv552644 CNV loss 21841781
nsv832040 CNV loss 17160897
nsv952707 CNV deletion 24416366

Relevant External Links for MIR3944 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3944

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3944 Gene

Disorders for MIR3944 Gene

Relevant External Links for MIR3944

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3944

No disorders were found for MIR3944 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3944 Gene

Publications for MIR3944 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. (PMID: 20498841) Liao J.Y. … Qu L.H. (PLoS ONE 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3944 Gene

Sources for MIR3944 Gene

Content
Loading form....