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Aliases for MIR3940 Gene

Subcategory (RNA class) for MIR3940 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3940 Gene

  • MicroRNA 3940 2 3 5
  • Hsa-Mir-3940 3
  • Mir-3940 3

External Ids for MIR3940 Gene

Previous GeneCards Identifiers for MIR3940 Gene

  • GC19U901447

Summaries for MIR3940 Gene

Entrez Gene Summary for MIR3940 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3940 Gene

MIR3940 (MicroRNA 3940) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Gene Expression and CDK-mediated phosphorylation and removal of Cdc6.

Additional gene information for MIR3940 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3940 Gene

Genomics for MIR3940 Gene

GeneHancer (GH) Regulatory Elements for MIR3940 Gene

Promoters and enhancers for MIR3940 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I006423 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.4 -8.2 -8159 3.2 HDGF PKNOX1 CLOCK ARNT ARID4B NEUROD1 SIN3A ZNF2 ZBTB7B IRF4 KHSRP GC19M006424 ZNF557 DUS3L ENSG00000267571 SNRPEP4 SAFB RANBP3 SAFB2 VMAC
GH19I006422 Enhancer 0.2 ENCODE 0.4 -5.6 -5574 0.2 GC19M006424 KHSRP MIR3940
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3940 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3940 Gene

Genomic Locations for MIR3940 Gene
chr19:6,416,410-6,416,511
(GRCh38/hg38)
Size:
102 bases
Orientation:
Minus strand
chr19:6,416,421-6,416,522
(GRCh37/hg19)

Genomic View for MIR3940 Gene

Genes around MIR3940 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3940 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3940 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3940 Gene

Proteins for MIR3940 Gene

Post-translational modifications for MIR3940 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3940 Gene

Domains & Families for MIR3940 Gene

Gene Families for MIR3940 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3940: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3940 Gene

Function for MIR3940 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3940 Gene

Localization for MIR3940 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3940 Gene

Pathways & Interactions for MIR3940 Gene

genes like me logo Genes that share pathways with MIR3940: view

Pathways by source for MIR3940 Gene

Interacting Proteins for MIR3940 Gene

Gene Ontology (GO) - Biological Process for MIR3940 Gene

None

No data available for SIGNOR curated interactions for MIR3940 Gene

Drugs & Compounds for MIR3940 Gene

No Compound Related Data Available

Transcripts for MIR3940 Gene

mRNA/cDNA for MIR3940 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3940 Gene

No ASD Table

Relevant External Links for MIR3940 Gene

GeneLoc Exon Structure for
MIR3940
ECgene alternative splicing isoforms for
MIR3940

Expression for MIR3940 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3940 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3940 Gene:

MIR3940
genes like me logo Genes that share expression patterns with MIR3940: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3940 Gene

Orthologs for MIR3940 Gene

Evolution for MIR3940 Gene

ENSEMBL:
Gene Tree for MIR3940 (if available)
TreeFam:
Gene Tree for MIR3940 (if available)

No data available for Orthologs for MIR3940 Gene

Paralogs for MIR3940 Gene

No data available for Paralogs for MIR3940 Gene

Variants for MIR3940 Gene

Sequence variations from dbSNP and Humsavar for MIR3940 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1001086313 -- 6,416,792(-) C/T upstream_transcript_variant
rs1003173010 -- 6,417,929(-) C/T upstream_transcript_variant
rs1003198351 -- 6,416,891(-) C/T upstream_transcript_variant
rs1003858537 -- 6,418,347(-) G/A upstream_transcript_variant
rs1004222905 -- 6,417,282(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3940 Gene

Variant ID Type Subtype PubMed ID
nsv833727 CNV loss 17160897

Additional Variant Information for MIR3940 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3940

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3940 Gene

Disorders for MIR3940 Gene

Additional Disease Information for MIR3940

No disorders were found for MIR3940 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3940 Gene

Publications for MIR3940 Gene

  1. Downregulation of miR-3940-5p promotes T-cell activity by targeting the cytokine receptor IL-2R gamma on human cutaneous T-cell lines. (PMID: 27502164) Wang Y … Zhang M (Immunobiology 2016) 3 58
  2. Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features. (PMID: 23228962) Sun Y … Gao W (Oncology reports 2013) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  5. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. (PMID: 20498841) Liao JY … Qu LH (PloS one 2010) 3 58

Products for MIR3940 Gene

Sources for MIR3940 Gene

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