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Aliases for MIR3917 Gene

Subcategory (RNA class) for MIR3917 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3917 Gene

  • MicroRNA 3917 2 3 5
  • Hsa-Mir-3917 3
  • Mir-3917 3

External Ids for MIR3917 Gene

Previous GeneCards Identifiers for MIR3917 Gene

  • GC01U903123
  • GC01M026237
  • GC01M026243
  • GC01M026246
  • GC01M025906

Summaries for MIR3917 Gene

Entrez Gene Summary for MIR3917 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3917 Gene

MIR3917 (MicroRNA 3917) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Immune response IL-23 signaling pathway and Retinoblastoma (RB) in Cancer.

Additional gene information for MIR3917 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3917 Gene

Genomics for MIR3917 Gene

Regulatory Elements for MIR3917 Gene

Enhancers for MIR3917 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H025903 1.4 ENCODE dbSUPER 0.7 +0.8 838 4 HDGF FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS GPN2 MTFR1L ENSG00000261349 ENSG00000207302 ENSG00000261025 ENSG00000231953 RPL39P7 PIGV LOC101928324 ENSG00000236528
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3917 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3917 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000003461 754 2201 HDGF FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS

Genomic Location for MIR3917 Gene

Chromosome:
1
Start:
25,906,362 bp from pter
End:
25,906,454 bp from pter
Size:
93 bases
Orientation:
Minus strand

Genomic View for MIR3917 Gene

Genes around MIR3917 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3917 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3917 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3917 Gene

Proteins for MIR3917 Gene

Post-translational modifications for MIR3917 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3917 Gene

Domains & Families for MIR3917 Gene

Gene Families for MIR3917 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3917: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3917 Gene

Function for MIR3917 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3917
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3917 Gene

Localization for MIR3917 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3917 Gene

Pathways & Interactions for MIR3917 Gene

genes like me logo Genes that share pathways with MIR3917: view

Pathways by source for MIR3917 Gene

Interacting Proteins for MIR3917 Gene

Gene Ontology (GO) - Biological Process for MIR3917 Gene

None

No data available for SIGNOR curated interactions for MIR3917 Gene

Drugs & Compounds for MIR3917 Gene

No Compound Related Data Available

Transcripts for MIR3917 Gene

mRNA/cDNA for MIR3917 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3917
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3917 Gene

No ASD Table

Relevant External Links for MIR3917 Gene

GeneLoc Exon Structure for
MIR3917
ECgene alternative splicing isoforms for
MIR3917

Expression for MIR3917 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3917 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3917 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x5.8), Brain - Frontal Cortex (BA9) (x5.3), Brain - Anterior cingulate cortex (BA24) (x5.0), and Brain - Cortex (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR3917 Gene:

MIR3917
genes like me logo Genes that share expression patterns with MIR3917: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3917 Gene

Orthologs for MIR3917 Gene

Evolution for MIR3917 Gene

ENSEMBL:
Gene Tree for MIR3917 (if available)
TreeFam:
Gene Tree for MIR3917 (if available)

No data available for Orthologs for MIR3917 Gene

Paralogs for MIR3917 Gene

No data available for Paralogs for MIR3917 Gene

Variants for MIR3917 Gene

Sequence variations from dbSNP and Humsavar for MIR3917 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000875160 -- 25,907,396(+) GCAAA(A/G)GCACA nc-transcript-variant, upstream-variant-2KB
rs1000939569 -- 25,906,886(+) AGTGC(A/C/G)CCACC intron-variant, upstream-variant-2KB
rs1001204320 -- 25,906,243(+) AGCGA(C/T)CCCCG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002281299 -- 25,906,038(+) CCCTT(C/G)AGACA intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs1004350276 -- 25,908,184(+) AGGAA(A/G)GTCCC nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3917 Gene

Variant ID Type Subtype PubMed ID
nsv834491 CNV loss 17160897
nsv834502 CNV gain 17160897

Relevant External Links for MIR3917 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3917

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3917 Gene

Disorders for MIR3917 Gene

Relevant External Links for MIR3917

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3917

No disorders were found for MIR3917 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3917 Gene

Publications for MIR3917 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3917 Gene

Sources for MIR3917 Gene

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