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Aliases for MIR380 Gene

Subcategory (RNA class) for MIR380 Gene


Quality Score for this RNA gene is


Aliases for MIR380 Gene

  • MicroRNA 380 2 3 5
  • Hsa-Mir-380 3
  • MIR380-3p 3
  • Mir-380 3
  • MIRN380 3

External Ids for MIR380 Gene

ORGUL Members for MIR380 Gene

Previous HGNC Symbols for MIR380 Gene

  • MIRN380

Previous GeneCards Identifiers for MIR380 Gene

  • GC14P100814
  • GC14P100906
  • GC14P101491
  • GC14P101235
  • GC14P101413
  • GC14P102072
  • GC14P102332

Summaries for MIR380 Gene

Entrez Gene Summary for MIR380 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR380 Gene

MIR380 (MicroRNA 380) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR380 Gene

Genomics for MIR380 Gene

Genomic Location for MIR380 Gene

101,025,017 bp from pter
101,025,077 bp from pter
61 bases
Plus strand

Genomic View for MIR380 Gene

Genes around MIR380 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR380 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR380 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR380 Gene

No data available for Regulatory Elements for MIR380 Gene

Proteins for MIR380 Gene

Post-translational modifications for MIR380 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR380 Gene

Domains & Families for MIR380 Gene

Gene Families for MIR380 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR380: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR380 Gene

Function for MIR380 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR380 Gene

Localization for MIR380 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR380 Gene

Pathways & Interactions for MIR380 Gene

SuperPathways for MIR380 Gene

No Data Available

Interacting Proteins for MIR380 Gene

Gene Ontology (GO) - Biological Process for MIR380 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR380 Gene

Transcripts for MIR380 Gene

mRNA/cDNA for MIR380 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR380 Gene

No ASD Table

Relevant External Links for MIR380 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR380 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR380 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR380 Gene:

genes like me logo Genes that share expression patterns with MIR380: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR380 Gene

Orthologs for MIR380 Gene

Evolution for MIR380 Gene

Gene Tree for MIR380 (if available)
Gene Tree for MIR380 (if available)

No data available for Orthologs for MIR380 Gene

Paralogs for MIR380 Gene

No data available for Paralogs for MIR380 Gene

Variants for MIR380 Gene

Sequence variations from dbSNP and Humsavar for MIR380 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs111835650 -- 101,023,377(+) ACGTA(C/T)GTAAC nc-transcript-variant, upstream-variant-2KB
rs111906529 -- 101,023,366(+) CTTTA(C/T)CTGTG nc-transcript-variant, upstream-variant-2KB
rs112914425 -- 101,024,532(+) CTTCA(C/G)TGACC upstream-variant-2KB
rs113746631 -- 101,024,381(+) CCTCA(A/T)GAAGA upstream-variant-2KB
rs116848752 -- 101,024,416(+) TTACA(C/G)AGGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR380 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
esv3635523 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv1426 CNV insertion 18451855
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Relevant External Links for MIR380 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR380 Gene

Disorders for MIR380 Gene

Relevant External Links for MIR380

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR380 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR380 Gene

Publications for MIR380 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. (PMID: 20871609) Swarbrick A. … Goga A. (Nat. Med. 2010) 3 64
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. (PMID: 15310658) Seitz H. … CavaillAc J. (Genome Res. 2004) 3 64

Products for MIR380 Gene

Sources for MIR380 Gene

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