Aliases for MIR379 Gene
Subcategory (RNA class) for MIR379 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR379 Gene
- HGNC: 31872
- Entrez Gene: 494328
- Ensembl: ENSG00000199088
- OMIM: 616358
- miRBase: hsa-mir-379
Previous HGNC Symbols for MIR379 Gene
- MIRN379
Previous GeneCards Identifiers for MIR379 Gene
- GC14P100811
- GC14P100903
- GC14P101488
- GC14P101230
- GC14P101801
- GC14P102095
- GC14P102329
- GC14P102499
Summaries for MIR379 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR379 Gene
MIR379 (MicroRNA 379) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR379 Gene
Genomics for MIR379 Gene
Regulatory Element Products
Genomic Location for MIR379 Gene
- Chromosome:
- 14
- Start:
- 101,022,066 bp from pter
- End:
- 101,022,132 bp from pter
- Size:
- 67 bases
- Orientation:
- Plus strand
Genomic View for MIR379 Gene
Genes around MIR379 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.31 by Ensembl
- 14q32.31 by Entrez Gene
- 14q32.31 by HGNC
MIR379 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR379 Gene
No data available for Regulatory Elements for MIR379 Gene
Proteins for MIR379 Gene
Post-translational modifications for MIR379 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR379
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR379
- Origene Custom Protein Services for MIR379
- Search GeneTex for Proteins for MIR379
Assay Products
No data available for DME Specific Peptides for MIR379 Gene
Domains & Families for MIR379 Gene
Gene Families for MIR379 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR379 Gene
Function for MIR379 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR379
-
- Search ViGene Biosciences for MIR379
CRISPR Products
- Browse CRISPR knockouts for MIR379
miRNA Products
- Search ViGene Biosciences for MIR379
-
Origene geneexpression products in human, mouse, rat for MIR379
- Browse OriGene miRNA Products For MIR379
Inhibitory RNA Products
- Search ViGene Biosciences for MIR379
Clone Products
- GenScript: Custom all cDNA clones Services for MIR379
- VectorBuilder custom plasmid, inducible vectors for MIR379
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR379
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR379
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR379 Gene
Localization for MIR379 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR379 Gene
Transcripts for MIR379 Gene
mRNA/cDNA for MIR379 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR379
miRNA Products
- Search ViGene Biosciences for MIR379
-
Origene geneexpression products in human, mouse, rat for MIR379
- Browse OriGene miRNA Products For MIR379
Inhibitory RNA Products
- Search ViGene Biosciences for MIR379
Clone Products
- GenScript: Custom all cDNA clones Services for MIR379
- VectorBuilder custom plasmid, inducible vectors for MIR379
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR379
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR379 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR379 Gene:
MIR379Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR379 Gene
Orthologs for MIR379 Gene
No data available for Orthologs for MIR379 Gene
Paralogs for MIR379 Gene
No data available for Paralogs for MIR379 Gene
Variants for MIR379 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1001056043 | -- | 101,022,619(+) | CAGTG(C/G)CAAGT | downstream-variant-500B, upstream-variant-2KB | |
| rs1001734264 | -- | 101,020,376(+) | CCATA(C/G)AGACC | upstream-variant-2KB | |
| rs1003412680 | -- | 101,021,384(+) | GGCCC(C/T)GTCTA | upstream-variant-2KB | |
| rs1003500241 | -- | 101,021,122(+) | GGAGG(A/C/G)TCAGG | upstream-variant-2KB | |
| rs1003855846 | -- | 101,021,267(+) | CACGG(A/G)GTATG | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3635521 | CNV | gain | 21293372 |
| nsv1040993 | CNV | gain | 25217958 |
| nsv1426 | CNV | insertion | 18451855 |
| nsv565859 | CNV | gain | 21841781 |
| nsv565860 | CNV | gain | 21841781 |
Relevant External Links for MIR379 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR379
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR379 Gene
Disorders for MIR379 Gene
Relevant External Links for MIR379
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR379
No disorders were found for MIR379 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR379 Gene
Publications for MIR379 Gene
- MicroRNA-379-5p inhibits tumor invasion and metastasis by targeting FAK/AKT signaling in hepatocellular carcinoma. (PMID: 26944318) Chen J.S. … Huang X.H. (Cancer Lett. 2016) 3 64
- microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis. (PMID: 25510864) de Guia R.M. … Herzig S. (EMBO J. 2015) 3 64
- miR-154* and miR-379 in the DLK1-DIO3 microRNA mega-cluster regulate epithelial to mesenchymal transition and bone metastasis of prostate cancer. (PMID: 25324143) Gururajan M. … Chung L.W. (Clin. Cancer Res. 2014) 3 64
- miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma. (PMID: 25231602) Yamamoto K. … Gemma A. (Oncol. Rep. 2014) 3 64
- Genetic variants may play an important role in mRNA-miRNA interaction: evidence for haplotype-dependent downregulation of ABCC2 (MRP2) by miRNA-379. (PMID: 24743544) Werk A.N. … Cascorbi I. (Pharmacogenet. Genomics 2014) 3 64
Products for MIR379 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR379
- Origene Custom Protein Services for MIR379
- Browse OriGene Inhibitory RNA Products For MIR379
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR379
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR379
- Browse OriGene miRNA Products For MIR379
- GenScript: Custom all cDNA clones Services for MIR379
- GenScript Custom Purified and Recombinant Proteins Services for MIR379
- GenScript Custom Assay Services for MIR379
- GenScript Custom overexpressing Cell Line Services for MIR379
- Browse GenScript CRISPR for MIR379
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR379
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR379
- VectorBuilder custom plasmid, inducible vectors for MIR379
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR379
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR379 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer