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Aliases for MIR379 Gene

Subcategory (RNA class) for MIR379 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR379 Gene

  • MicroRNA 379 2 3
  • Hsa-Mir-379 3
  • MIRN379 3

External Ids for MIR379 Gene

Previous HGNC Symbols for MIR379 Gene

  • MIRN379

Previous GeneCards Identifiers for MIR379 Gene

  • GC14P100811
  • GC14P100903
  • GC14P101488

Summaries for MIR379 Gene

Entrez Gene Summary for MIR379 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR379 Gene

MIR379 (MicroRNA 379) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR379 Gene

Genomics for MIR379 Gene

Genomic Location for MIR379 Gene

Start:
101,022,051 bp from pter
End:
101,022,159 bp from pter
Size:
109 bases
Orientation:
Plus strand

Genomic View for MIR379 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR379 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR379 Gene

No data available for Regulatory Elements for MIR379 Gene

Proteins for MIR379 Gene

Post-translational modifications for MIR379 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR379 Gene

Domains for MIR379 Gene

Gene Families for MIR379 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR379: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR379 Gene

Function for MIR379 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR379 Gene

Localization for MIR379 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR379 Gene

Pathways for MIR379 Gene

SuperPathways for MIR379 Gene

No Data Available

Interacting Proteins for MIR379 Gene

Gene Ontology (GO) - Biological Process for MIR379 Gene

None

No data available for Pathways by source for MIR379 Gene

Transcripts for MIR379 Gene

mRNA/cDNA for MIR379 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR379 Gene

No ASD Table

Relevant External Links for MIR379 Gene

GeneLoc Exon Structure for
MIR379
ECgene alternative splicing isoforms for
MIR379

Expression for MIR379 Gene

mRNA expression in normal human tissues for MIR379 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR379: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR379 Gene

Orthologs for MIR379 Gene

Evolution for MIR379 Gene

ENSEMBL:
Gene Tree for MIR379 (if available)
TreeFam:
Gene Tree for MIR379 (if available)

No data available for Orthologs for MIR379 Gene

Paralogs for MIR379 Gene

No data available for Paralogs for MIR379 Gene

Variants for MIR379 Gene

Sequence variations from dbSNP and Humsavar for MIR379 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs7142412 -- 101,020,664(+) ATACT(C/G)CATCC upstream-variant-2KB
rs7143098 -- 101,021,314(+) GAGGG(A/G)GCAGG upstream-variant-2KB
rs7143252 -- 101,021,284(+) AATCT(C/G)TTAGA upstream-variant-2KB
rs7144294 -- 101,021,123(+) GAGGG(C/T)CAGGG upstream-variant-2KB
rs10130496 -- 101,020,966(+) CACAA(C/T)GCTAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR379 Gene

Variant ID Type Subtype PubMed ID
nsv1426 CNV Insertion 18451855

Relevant External Links for MIR379 Gene

HapMap Linkage Disequilibrium report
MIR379

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR379 Gene

Disorders for MIR379 Gene

No disorders were found for MIR379 Gene.

No data available for UniProtKB/Swiss-Prot for MIR379 Gene

Publications for MIR379 Gene

  1. A pancreatic islet-specific microRNA regulates insulin secretion. (PMID: 15538371) Poy M.N. … Stoffel M. (Nature 2004) 3
  2. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3
  3. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A. … Zavolan M. (BMC Bioinformatics 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR379 Gene

Sources for MIR379 Gene

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