Aliases for MIR379 Gene
Subcategory (RNA class) for MIR379 Gene
Quality Score for this RNA gene is
External Ids for MIR379 Gene
- HGNC: 31872
- Entrez Gene: 494328
- Ensembl: ENSG00000199088
- OMIM: 616358
- miRBase: hsa-mir-379
Previous HGNC Symbols for MIR379 Gene
- MIRN379
Previous GeneCards Identifiers for MIR379 Gene
- GC14P100811
- GC14P100903
- GC14P101488
- GC14P101230
- GC14P101801
- GC14P102095
- GC14P102329
- GC14P102499
- GC14P102676
- GC14P102848
Summaries for MIR379 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR379 Gene
MIR379 (MicroRNA 379) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR379 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR379 Gene
Genomics for MIR379 Gene
GeneHancer (GH) Regulatory Elements for MIR379 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH14I101020 | Enhancer | 0.5 | ENCODE | 550.8 | -1.1 | -1081 | 1 | KLF1 ZNF488 KLF8 ZNF248 ZBTB1 | MIR379 GC14P103195 MEG9 ENSG00000222185 MEG8 |
Regulatory Element Products
Genomic Locations for MIR379 Gene
- chr14:101,022,066-101,022,132
- (GRCh38/hg38)
- Size:
- 67 bases
- Orientation:
- Plus strand
- chr14:101,488,366-101,488,491
- (GRCh37/hg19)
Genomic View for MIR379 Gene
- Cytogenetic band:
-
- 14q32.31 by Ensembl
- 14q32.31 by Entrez Gene
- 14q32.31 by HGNC


RefSeq DNA sequence for MIR379 Gene
Proteins for MIR379 Gene
Post-translational modifications for MIR379 Gene
Antibody Products
- Search GeneTex for Antibodies for MIR379
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR379
- Origene Custom Protein Services for MIR379
- Search GeneTex for Proteins for MIR379
No data available for DME Specific Peptides for MIR379 Gene
Domains & Families for MIR379 Gene
Gene Families for MIR379 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR379 Gene
Function for MIR379 Gene
Phenotypes From GWAS Catalog for MIR379 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR379
-
- Search ViGene Biosciences for MIR379
CRISPR Products
- Browse CRISPR knockouts for MIR379
- Applied Biological Materials CRISPR for MIR379
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR379
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR379 Gene
Localization for MIR379 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR379 Gene
Transcripts for MIR379 Gene
mRNA/cDNA for MIR379 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR379
- Applied Biological Materials CRISPR for MIR379
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR379
Clone Products
- GenScript: Custom all cDNA clones Services for MIR379
- VectorBuilder custom plasmid, inducible vectors for MIR379
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR379
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR379
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR379 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR379 Gene:
MIR379Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR379 Gene
Orthologs for MIR379 Gene
No data available for Orthologs for MIR379 Gene
Paralogs for MIR379 Gene
No data available for Paralogs for MIR379 Gene
Variants for MIR379 Gene
SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1001056043 | -- | 101,022,619(+) | C/G | downstream_transcript_variant | |
rs1001734264 | -- | 101,020,376(+) | C/G | upstream_transcript_variant | |
rs1003412680 | -- | 101,021,384(+) | C/T | upstream_transcript_variant | |
rs1003500241 | -- | 101,021,122(+) | G/A/C | upstream_transcript_variant | |
rs1003855846 | -- | 101,021,267(+) | G/A | upstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3635521 | CNV | gain | 21293372 |
nsv1040993 | CNV | gain | 25217958 |
nsv1426 | CNV | insertion | 18451855 |
nsv565859 | CNV | gain | 21841781 |
nsv565860 | CNV | gain | 21841781 |
Additional Variant Information for MIR379 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR379
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR379 Gene
Disorders for MIR379 Gene
Additional Disease Information for MIR379
No disorders were found for MIR379 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR379 Gene
Publications for MIR379 Gene
- Suppression of EIF4G2 by miR-379 potentiates the cisplatin chemosensitivity in nonsmall cell lung cancer cells. (PMID: 28117895) Hao GJ … Zhang BB (FEBS letters 2017) 3 58
- MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. (PMID: 27781416) Li Z … Wu WK (Journal of cellular and molecular medicine 2017) 3 58
- MicroRNA-379-5p inhibits tumor invasion and metastasis by targeting FAK/AKT signaling in hepatocellular carcinoma. (PMID: 26944318) Chen JS … Huang XH (Cancer letters 2016) 3 58
- microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis. (PMID: 25510864) de Guia RM … Herzig S (The EMBO journal 2015) 3 58
- miR-154* and miR-379 in the DLK1-DIO3 microRNA mega-cluster regulate epithelial to mesenchymal transition and bone metastasis of prostate cancer. (PMID: 25324143) Gururajan M … Chung LW (Clinical cancer research : an official journal of the American Association for Cancer Research 2014) 3 58
Products for MIR379 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR379
- VectorBuilder custom plasmid, inducible vectors for MIR379
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR379
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR379
- Search GeneTex for Proteins for MIR379
Sources for MIR379 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew