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Aliases for MIR378I Gene

Subcategory (RNA class) for MIR378I Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR378I Gene

  • MicroRNA 378i 2 3 5
  • Hsa-Mir-378i 3

External Ids for MIR378I Gene

Previous GeneCards Identifiers for MIR378I Gene

  • GC22U900799
  • GC22M042322
  • GC22M041926

Summaries for MIR378I Gene

Entrez Gene Summary for MIR378I Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378I Gene

MIR378I (MicroRNA 378i) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378I Gene

Genomics for MIR378I Gene

Genomic Location for MIR378I Gene

Chromosome:
22
Start:
41,923,222 bp from pter
End:
41,923,297 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR378I Gene

Genes around MIR378I on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378I Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378I Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378I Gene

ORGUL Member Location for MIR378I Gene

ORGUL Member Location for MIR378I gene

No data available for Regulatory Elements for MIR378I Gene

Proteins for MIR378I Gene

Post-translational modifications for MIR378I Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378I Gene

Domains & Families for MIR378I Gene

Gene Families for MIR378I Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378I: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378I Gene

Function for MIR378I Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378I Gene

Localization for MIR378I Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378I Gene

Pathways & Interactions for MIR378I Gene

SuperPathways for MIR378I Gene

No Data Available

Interacting Proteins for MIR378I Gene

Gene Ontology (GO) - Biological Process for MIR378I Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR378I Gene

Drugs & Compounds for MIR378I Gene

No Compound Related Data Available

Transcripts for MIR378I Gene

mRNA/cDNA for MIR378I Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378I Gene

No ASD Table

Relevant External Links for MIR378I Gene

GeneLoc Exon Structure for
MIR378I
ECgene alternative splicing isoforms for
MIR378I

Expression for MIR378I Gene

mRNA expression in normal human tissues for MIR378I Gene

mRNA differential expression in normal tissues according to GTEx for MIR378I Gene

This gene is overexpressed in Spleen (x16.6), Small Intestine - Terminal Ileum (x9.4), and Whole Blood (x9.3).
genes like me logo Genes that share expression patterns with MIR378I: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR378I Gene

Orthologs for MIR378I Gene

Evolution for MIR378I Gene

ENSEMBL:
Gene Tree for MIR378I (if available)
TreeFam:
Gene Tree for MIR378I (if available)

No data available for Orthologs for MIR378I Gene

Paralogs for MIR378I Gene

No data available for Paralogs for MIR378I Gene

Variants for MIR378I Gene

Sequence variations from dbSNP and Humsavar for MIR378I Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs5996086 -- 41,924,257(+) tgagg(C/T)gggcg upstream-variant-2KB
rs76744864 -- 41,923,158(+) GCAGG(A/G)GTCTA downstream-variant-500B
rs183353138 -- 41,923,075(+) TTCCA(A/G)GCTGG downstream-variant-500B
rs150540731 -- 41,923,397(+) GAGGC(A/G)GCTGA upstream-variant-2KB
rs187201501 -- 41,923,764(+) CAGCA(C/T)GTTCC upstream-variant-2KB

Relevant External Links for MIR378I Gene

HapMap Linkage Disequilibrium report
MIR378I

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR378I Gene

Disorders for MIR378I Gene

Relevant External Links for MIR378I

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR378I

No disorders were found for MIR378I Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378I Gene

Publications for MIR378I Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR378I Gene

Sources for MIR378I Gene

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