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Aliases for MIR378H Gene

Subcategory (RNA class) for MIR378H Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR378H Gene

  • MicroRNA 378h 2 3 5
  • Hsa-Mir-378h 3

External Ids for MIR378H Gene

Previous GeneCards Identifiers for MIR378H Gene

  • GC05U901576
  • GC05P154211

Summaries for MIR378H Gene

Entrez Gene Summary for MIR378H Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378H Gene

MIR378H (MicroRNA 378h) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378H Gene

Genomics for MIR378H Gene

Regulatory Elements for MIR378H Gene

Enhancers for MIR378H Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G154828 1.1 ENCODE dbSUPER 0.7 +0.3 327 2.8 HDGF FOXA2 NFIB ZSCAN4 RAD21 THRB ZBTB7B RARA ZNF121 EGR1 CNOT8 FAXDC2 LARP1 MIR378H
GH05G154834 1.6 Ensembl ENCODE dbSUPER 0.4 +5.6 5624 1.7 PKNOX1 FOXA2 MLX ARNT ARID4B FEZF1 ZNF2 YY1 ZNF766 FOS CNOT8 SAP30L-AS1 MFAP3 GEMIN5 FAXDC2 MIR378H
GH05G154825 0.8 FANTOM5 0.7 -3.6 -3576 0.3 HINFP TAL1 ZNF175 FOSL1 ZNF766 NFE2 CREM ZBTB11 MAFG ATF2 CNOT8 GEMIN5 KIF4B ENSG00000277039 MIR378H
GH05G154844 1.1 ENCODE dbSUPER 0.4 +15.5 15461 0.4 ELF3 PKNOX1 ATF1 FOXA2 NFIB MLX ARID4B RAD21 GATA4 GATA2 CNOT8 MIR378H
GH05G154843 0.9 ENCODE 0.4 +13.7 13698 0.2 FOXA2 ATF1 MLX ARID4B DMAP1 SP5 MIER2 PPARG KAT8 MBD2 MIR378H CNOT8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR378H on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR378H Gene

Chromosome:
5
Start:
154,829,458 bp from pter
End:
154,829,540 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR378H Gene

Genes around MIR378H on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378H Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378H Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378H Gene

Proteins for MIR378H Gene

Post-translational modifications for MIR378H Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378H Gene

Domains & Families for MIR378H Gene

Gene Families for MIR378H Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378H: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378H Gene

Function for MIR378H Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378H Gene

Localization for MIR378H Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378H Gene

Pathways & Interactions for MIR378H Gene

SuperPathways for MIR378H Gene

No Data Available

Interacting Proteins for MIR378H Gene

Gene Ontology (GO) - Biological Process for MIR378H Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR378H Gene

Drugs & Compounds for MIR378H Gene

No Compound Related Data Available

Transcripts for MIR378H Gene

mRNA/cDNA for MIR378H Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378H Gene

No ASD Table

Relevant External Links for MIR378H Gene

GeneLoc Exon Structure for
MIR378H
ECgene alternative splicing isoforms for
MIR378H

Expression for MIR378H Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR378H Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378H Gene:

MIR378H
genes like me logo Genes that share expression patterns with MIR378H: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378H Gene

Orthologs for MIR378H Gene

Evolution for MIR378H Gene

ENSEMBL:
Gene Tree for MIR378H (if available)
TreeFam:
Gene Tree for MIR378H (if available)

No data available for Orthologs for MIR378H Gene

Paralogs for MIR378H Gene

No data available for Paralogs for MIR378H Gene

Variants for MIR378H Gene

Sequence variations from dbSNP and Humsavar for MIR378H Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1002515682 -- 154,829,036(+) TCCAG(A/G)CATGC intron-variant, upstream-variant-2KB
rs1004668166 -- 154,829,045(+) GCGCC(A/G)CCATG intron-variant, upstream-variant-2KB
rs1004822971 -- 154,829,656(+) CCAAT(A/T)AAGAA intron-variant, downstream-variant-500B
rs1005019462 -- 154,829,342(+) ACTTG(A/T)GGATC intron-variant, upstream-variant-2KB
rs1006286886 -- 154,828,054(+) TCTGT(C/T)GCTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR378H Gene

Variant ID Type Subtype PubMed ID
nsv830521 CNV gain 17160897

Relevant External Links for MIR378H Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR378H

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378H Gene

Disorders for MIR378H Gene

Relevant External Links for MIR378H

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR378H

No disorders were found for MIR378H Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378H Gene

Publications for MIR378H Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR378H Gene

Sources for MIR378H Gene

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