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Aliases for MIR378G Gene

Subcategory (RNA class) for MIR378G Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR378G Gene

  • MicroRNA 378g 2 3 5
  • Hsa-Mir-378g 3

External Ids for MIR378G Gene

Previous GeneCards Identifiers for MIR378G Gene

  • GC01U903253
  • GC01M095212

Summaries for MIR378G Gene

Entrez Gene Summary for MIR378G Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378G Gene

MIR378G (MicroRNA 378g) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR378G Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378G Gene

Genomics for MIR378G Gene

GeneHancer (GH) Regulatory Elements for MIR378G Gene

Promoters and enhancers for MIR378G Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I094743 Enhancer 0.4 ENCODE dbSUPER 550.8 +1.8 1788 1.5 GC01M094659 MIR378G SLC44A3-AS1
GH01I094746 Enhancer 0.4 ENCODE 550.8 -1.2 -1150 0.2 REST NR2F2 MIR378G SLC44A3 GC01M094794 SLC44A3-AS1
GH01I094753 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -9.1 -9083 3.7 ATF1 ZNF48 TCF12 FOS RXRA REST MEF2D NFIL3 MAFF MIER3 SLC44A3 F3 SLC44A3-AS1 ARHGAP29 MIG7 RWDD3 MIR378G GC01M094794
GH01I094757 Enhancer 0.8 Ensembl ENCODE 0.4 -12.2 -12243 1.3 SCRT1 SOX13 FOXA2 RXRA ZNF449 NR2F2 RARA BCL6 SMAD4 TRIM28 SLC44A3 F3 SLC44A3-AS1 MIR378G GC01M094794
GH01I094782 Enhancer 1 Ensembl ENCODE 0.3 -37.8 -37787 2.3 PKNOX1 KLF17 MZF1 ZNF76 FEZF1 RFX5 ZNF335 ZEB2 TSHZ1 ZFP69B SLC44A3 SLC44A3-AS1 F3 GC01M094794 MIR378G
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR378G on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR378G Gene

Genomic Locations for MIR378G Gene
chr1:94,745,860-94,745,900
(GRCh38/hg38)
Size:
41 bases
Orientation:
Minus strand
chr1:95,211,416-95,211,456
(GRCh37/hg19)

Genomic View for MIR378G Gene

Genes around MIR378G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378G Gene

ORGUL Member Location for MIR378G Gene

ORGUL Member Location for MIR378G gene

Proteins for MIR378G Gene

Post-translational modifications for MIR378G Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378G Gene

Domains & Families for MIR378G Gene

Gene Families for MIR378G Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378G: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378G Gene

Function for MIR378G Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378G Gene

Localization for MIR378G Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR378G Gene

Pathways & Interactions for MIR378G Gene

SuperPathways for MIR378G Gene

No Data Available

Interacting Proteins for MIR378G Gene

Gene Ontology (GO) - Biological Process for MIR378G Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR378G Gene

Drugs & Compounds for MIR378G Gene

No Compound Related Data Available

Transcripts for MIR378G Gene

mRNA/cDNA for MIR378G Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378G Gene

No ASD Table

Relevant External Links for MIR378G Gene

GeneLoc Exon Structure for
MIR378G
ECgene alternative splicing isoforms for
MIR378G

Expression for MIR378G Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378G Gene:

MIR378G
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378G Gene

Orthologs for MIR378G Gene

Evolution for MIR378G Gene

ENSEMBL:
Gene Tree for MIR378G (if available)
TreeFam:
Gene Tree for MIR378G (if available)

No data available for Orthologs for MIR378G Gene

Paralogs for MIR378G Gene

No data available for Paralogs for MIR378G Gene

Variants for MIR378G Gene

Sequence variations from dbSNP and Humsavar for MIR378G Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000391767 -- 94,745,813(-) A/T downstream_transcript_variant
rs1000768638 -- 94,747,662(-) G/C upstream_transcript_variant
rs1000824824 -- 94,746,118(-) G/T upstream_transcript_variant
rs1001035860 -- 94,747,583(-) T/C upstream_transcript_variant
rs1001137147 -- 94,747,345(-) T/C upstream_transcript_variant

Additional Variant Information for MIR378G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR378G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR378G Gene

Disorders for MIR378G Gene

Additional Disease Information for MIR378G

No disorders were found for MIR378G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378G Gene

Publications for MIR378G Gene

  1. MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1. (PMID: 26473472) Lin T … Peng G (International journal of radiation biology 2015) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR378G Gene

Sources for MIR378G Gene

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