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Aliases for MIR378G Gene

Subcategory (RNA class) for MIR378G Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR378G Gene

  • MicroRNA 378g 2 3 5
  • Hsa-Mir-378g 3

External Ids for MIR378G Gene

Previous GeneCards Identifiers for MIR378G Gene

  • GC01U903253
  • GC01M095212

Summaries for MIR378G Gene

Entrez Gene Summary for MIR378G Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378G Gene

MIR378G (MicroRNA 378g) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378G Gene

Genomics for MIR378G Gene

Regulatory Elements for MIR378G Gene

Enhancers for MIR378G Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G094753 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -9.1 -9083 3.7 ATF1 SIN3A ZNF48 TCF12 FOS REST MEF2D MIER3 MAFF NR2C1 SLC44A3 F3 SLC44A3-AS1 MIR378G GC01M094794
GH01G094743 0.6 ENCODE dbSUPER 0.7 +1.8 1788 1.5 NR3C1 MIR378G GC01M094659
GH01G094757 0.9 Ensembl ENCODE 0.4 -12.2 -12244 1.3 SOX13 SCRT1 NR2F2 RARA SMARCA4 SMAD4 NFE2 BCL6 TRIM28 SLC44A3 F3 SLC44A3-AS1 MIR378G GC01M094794
GH01G094746 0.5 ENCODE 0.7 -1.2 -1150 0.3 CTCF SMARCA4 NR2F6 REST NR2F2 SLC44A3 MIR378G GC01M094794
GH01G094782 1.1 Ensembl ENCODE 0.3 -37.8 -37788 2.3 PKNOX1 ZNF76 KLF17 FEZF1 RFX5 TCF12 TSHZ1 ZEB2 ZFP69B GLIS1 SLC44A3 SLC44A3-AS1 F3 GC01M094794 MIR378G
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR378G on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR378G Gene

Chromosome:
1
Start:
94,745,860 bp from pter
End:
94,745,900 bp from pter
Size:
41 bases
Orientation:
Minus strand

Genomic View for MIR378G Gene

Genes around MIR378G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378G Gene

ORGUL Member Location for MIR378G Gene

ORGUL Member Location for MIR378G gene

Proteins for MIR378G Gene

Post-translational modifications for MIR378G Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378G Gene

Domains & Families for MIR378G Gene

Gene Families for MIR378G Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378G: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378G Gene

Function for MIR378G Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378G Gene

Localization for MIR378G Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378G Gene

Pathways & Interactions for MIR378G Gene

SuperPathways for MIR378G Gene

No Data Available

Interacting Proteins for MIR378G Gene

Gene Ontology (GO) - Biological Process for MIR378G Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR378G Gene

Transcripts for MIR378G Gene

mRNA/cDNA for MIR378G Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378G Gene

No ASD Table

Relevant External Links for MIR378G Gene

GeneLoc Exon Structure for
MIR378G
ECgene alternative splicing isoforms for
MIR378G

Expression for MIR378G Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378G Gene:

MIR378G
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378G Gene

Orthologs for MIR378G Gene

Evolution for MIR378G Gene

ENSEMBL:
Gene Tree for MIR378G (if available)
TreeFam:
Gene Tree for MIR378G (if available)

No data available for Orthologs for MIR378G Gene

Paralogs for MIR378G Gene

No data available for Paralogs for MIR378G Gene

Variants for MIR378G Gene

Sequence variations from dbSNP and Humsavar for MIR378G Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000391767 -- 94,745,813(+) GACAG(A/T)TGAAG intron-variant, downstream-variant-500B
rs1000768638 -- 94,747,662(+) ACCTG(C/G)GTCTG intron-variant, upstream-variant-2KB
rs1000824824 -- 94,746,118(+) CTTGG(G/T)TGAGA intron-variant, upstream-variant-2KB
rs1001035860 -- 94,747,583(+) CTGCC(C/T)GGTGG intron-variant, upstream-variant-2KB
rs1001137147 -- 94,747,345(+) GGGGA(C/T)TGGGC intron-variant, upstream-variant-2KB

Relevant External Links for MIR378G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR378G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR378G Gene

Disorders for MIR378G Gene

Relevant External Links for MIR378G

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR378G

No disorders were found for MIR378G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378G Gene

Publications for MIR378G Gene

  1. MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1. (PMID: 26473472) Lin T. … Peng G. (Int. J. Radiat. Biol. 2015) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR378G Gene

Sources for MIR378G Gene

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