Aliases for MIR378G Gene
Subcategory (RNA class) for MIR378G Gene
miRNA
Quality Score for this RNA gene is
8
External Ids for MIR378G Gene
- HGNC: 41785
- Entrez Gene: 100616321
- Ensembl: ENSG00000263526
- miRBase: hsa-mir-378g
ORGUL Members for MIR378G Gene
Previous GeneCards Identifiers for MIR378G Gene
- GC01U903253
- GC01M095212
Summaries for MIR378G Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR378G Gene
MIR378G (MicroRNA 378g) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378G Gene
Genomics for MIR378G Gene
Regulatory Elements for MIR378G Gene
Enhancers for MIR378G Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G094753 | 1.7 | FANTOM5 Ensembl ENCODE dbSUPER | 0.4 | -9.1 | -9083 | 3.7 | ATF1 SIN3A ZNF48 TCF12 FOS REST MEF2D MIER3 MAFF NR2C1 | SLC44A3 F3 SLC44A3-AS1 MIR378G GC01M094794 |
| GH01G094743 | 0.6 | ENCODE dbSUPER | 0.7 | +1.8 | 1788 | 1.5 | NR3C1 | MIR378G GC01M094659 |
| GH01G094757 | 0.9 | Ensembl ENCODE | 0.4 | -12.2 | -12244 | 1.3 | SOX13 SCRT1 NR2F2 RARA SMARCA4 SMAD4 NFE2 BCL6 TRIM28 | SLC44A3 F3 SLC44A3-AS1 MIR378G GC01M094794 |
| GH01G094746 | 0.5 | ENCODE | 0.7 | -1.2 | -1150 | 0.3 | CTCF SMARCA4 NR2F6 REST NR2F2 | SLC44A3 MIR378G GC01M094794 |
| GH01G094782 | 1.1 | Ensembl ENCODE | 0.3 | -37.8 | -37788 | 2.3 | PKNOX1 ZNF76 KLF17 FEZF1 RFX5 TCF12 TSHZ1 ZEB2 ZFP69B GLIS1 | SLC44A3 SLC44A3-AS1 F3 GC01M094794 MIR378G |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR378G on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR378G Gene
- Chromosome:
- 1
- Start:
- 94,745,860 bp from pter
- End:
- 94,745,900 bp from pter
- Size:
- 41 bases
- Orientation:
- Minus strand
Genomic View for MIR378G Gene
Genes around MIR378G on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p21.3 by Ensembl
- 1p21.3 by Entrez Gene
- 1p21.3 by HGNC
MIR378G Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR378G Gene
ORGUL Member Location for MIR378G Gene
Proteins for MIR378G Gene
Post-translational modifications for MIR378G Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR378G
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR378G
- Origene Custom Protein Services for MIR378G
- Search GeneTex for Proteins for MIR378G
No data available for DME Specific Peptides for MIR378G Gene
Domains & Families for MIR378G Gene
Gene Families for MIR378G Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378G Gene
Function for MIR378G Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR378G
-
- Search ViGene Biosciences for MIR378G
miRNA Products
- Search ViGene Biosciences for MIR378G
Inhibitory RNA Products
- Search ViGene Biosciences for MIR378G
Clone Products
- GenScript: Custom all cDNA clones Services for MIR378G
- VectorBuilder custom plasmid, inducible vectors for MIR378G
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR378G
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378G Gene
Localization for MIR378G Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378G Gene
Transcripts for MIR378G Gene
mRNA/cDNA for MIR378G Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
miRNA Products
- Search ViGene Biosciences for MIR378G
Inhibitory RNA Products
- Search ViGene Biosciences for MIR378G
Clone Products
- GenScript: Custom all cDNA clones Services for MIR378G
- VectorBuilder custom plasmid, inducible vectors for MIR378G
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR378G
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for MIR378G Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR378G Gene:
MIR378G
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378G Gene
Orthologs for MIR378G Gene
No data available for Orthologs for MIR378G Gene
Paralogs for MIR378G Gene
No data available for Paralogs for MIR378G Gene
Variants for MIR378G Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000391767 | -- | 94,745,813(+) | GACAG(A/T)TGAAG | intron-variant, downstream-variant-500B | |
| rs1000768638 | -- | 94,747,662(+) | ACCTG(C/G)GTCTG | intron-variant, upstream-variant-2KB | |
| rs1000824824 | -- | 94,746,118(+) | CTTGG(G/T)TGAGA | intron-variant, upstream-variant-2KB | |
| rs1001035860 | -- | 94,747,583(+) | CTGCC(C/T)GGTGG | intron-variant, upstream-variant-2KB | |
| rs1001137147 | -- | 94,747,345(+) | GGGGA(C/T)TGGGC | intron-variant, upstream-variant-2KB |
Relevant External Links for MIR378G Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR378G
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR378G Gene
Disorders for MIR378G Gene
Relevant External Links for MIR378G
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR378G
No disorders were found for MIR378G Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378G Gene
Publications for MIR378G Gene
- MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1. (PMID: 26473472) Lin T. … Peng G. (Int. J. Radiat. Biol. 2015) 3 64
- Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR378G Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Custom Antibody Services
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- Custom Assay Services
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- Origene Custom Protein Services for MIR378G
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Custom all cDNA clones Services for MIR378G
- GenScript Custom Purified and Recombinant Proteins Services for MIR378G
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- CloneReady with Over 120,000 Genes
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Search GeneTex for Antibodies for MIR378G
- Search GeneTex for Proteins for MIR378G
- Search ViGene Biosciences for MIR378G
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR378G
- VectorBuilder custom plasmid, inducible vectors for MIR378G
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR378G
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR378G Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
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- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio