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Aliases for MIR378D2 Gene

Subcategory (RNA class) for MIR378D2 Gene


Quality Score for this RNA gene is


Aliases for MIR378D2 Gene

  • MicroRNA 378d-2 2 3 5
  • Hsa-Mir-378d-2 3
  • Mir-378d-2 3

External Ids for MIR378D2 Gene

Previous GeneCards Identifiers for MIR378D2 Gene

  • GC08U901566
  • GC08M094929

Summaries for MIR378D2 Gene

Entrez Gene Summary for MIR378D2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378D2 Gene

MIR378D2 (MicroRNA 378d-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR378D2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378D2 Gene

Genomics for MIR378D2 Gene

Regulatory Elements for MIR378D2 Gene

Enhancers for MIR378D2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H093911 0.7 ENCODE dbSUPER 0.7 +3.5 3526 2.2 CEBPB CEBPG PDP1 FAM92A LINC00535 GC08P093909 MIR378D2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR378D2 on UCSC Golden Path with GeneCards custom track

Promoters for MIR378D2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000227107 -981 2201 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207 SP3 SP5

Genomic Locations for MIR378D2 Gene

Genomic Locations for MIR378D2 Gene
98 bases
Minus strand

Genomic View for MIR378D2 Gene

Genes around MIR378D2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378D2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378D2 Gene

ORGUL Member Location for MIR378D2 Gene

ORGUL Member Location for MIR378D2 gene

Proteins for MIR378D2 Gene

Post-translational modifications for MIR378D2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378D2 Gene

Domains & Families for MIR378D2 Gene

Gene Families for MIR378D2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378D2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378D2 Gene

Function for MIR378D2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378D2 Gene

Localization for MIR378D2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR378D2 Gene

Pathways & Interactions for MIR378D2 Gene

SuperPathways for MIR378D2 Gene

No Data Available

Interacting Proteins for MIR378D2 Gene

Gene Ontology (GO) - Biological Process for MIR378D2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR378D2 Gene

Drugs & Compounds for MIR378D2 Gene

No Compound Related Data Available

Transcripts for MIR378D2 Gene

mRNA/cDNA for MIR378D2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378D2 Gene

No ASD Table

Relevant External Links for MIR378D2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR378D2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR378D2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR378D2 Gene

This gene is overexpressed in Testis (x11.3) and Adrenal Gland (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR378D2 Gene:

genes like me logo Genes that share expression patterns with MIR378D2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378D2 Gene

Orthologs for MIR378D2 Gene

Evolution for MIR378D2 Gene

Gene Tree for MIR378D2 (if available)
Gene Tree for MIR378D2 (if available)

No data available for Orthologs for MIR378D2 Gene

Paralogs for MIR378D2 Gene

No data available for Paralogs for MIR378D2 Gene

Variants for MIR378D2 Gene

Sequence variations from dbSNP and Humsavar for MIR378D2 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs372548037 Uncertain significance 93,917,057(+) AGAAT(A/C/T)GTTTG upstream-variant-2KB, utr-variant-5-prime
rs764874879 Uncertain significance 93,916,982(+) GCTCC(A/C/G)GGAGC upstream-variant-2KB, utr-variant-5-prime
rs863224159 Uncertain significance 93,917,811(+) CCTCT(-/GCCGCCGCCTCCTC)AATGA intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs4469422 Benign 93,916,851(+) TCCCC(A/G/T)CCCAC upstream-variant-2KB
rs1001038662 -- 93,917,524(+) GGGCC(A/G)GGCAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR378D2 Gene

Variant ID Type Subtype PubMed ID
nsv1022473 CNV loss 25217958

Relevant External Links for MIR378D2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378D2 Gene

Disorders for MIR378D2 Gene

Relevant External Links for MIR378D2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR378D2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378D2 Gene

Publications for MIR378D2 Gene

  1. Exploring the molecular pathogenesis and biomarkers of high risk oral premalignant lesions on the basis of long noncoding RNA expression profiling by serial analysis of gene expression. (PMID: 28418939) Jia H … Sun Z (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2017) 2 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  5. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E … Cuppen E (Genome research 2006) 3 60

Products for MIR378D2 Gene

Sources for MIR378D2 Gene

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