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Aliases for MIR378D1 Gene

Subcategory (RNA class) for MIR378D1 Gene


Quality Score for this RNA gene is


Aliases for MIR378D1 Gene

  • MicroRNA 378d-1 2 3 5
  • Hsa-Mir-378d-1 3
  • Mir-378d-1 3

External Ids for MIR378D1 Gene

Previous GeneCards Identifiers for MIR378D1 Gene

  • GC04U901509
  • GC04M005926

Summaries for MIR378D1 Gene

Entrez Gene Summary for MIR378D1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378D1 Gene

MIR378D1 (MicroRNA 378d-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378D1 Gene

Genomics for MIR378D1 Gene

Regulatory Elements for MIR378D1 Gene

Enhancers for MIR378D1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F005912 0.4 ENCODE 0.4 +10.6 10568 0.6 BCL11A SCRT2 TEAD4 MAX ZNF266 POU5F1 CRMP1 MIR378D1
GH04F005905 0.2 ENCODE 0.3 +17.3 17320 0.2 ZNF680 REST CRMP1 MIR378D1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR378D1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR378D1 Gene

5,923,275 bp from pter
5,923,328 bp from pter
54 bases
Minus strand

Genomic View for MIR378D1 Gene

Genes around MIR378D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378D1 Gene

ORGUL Member Location for MIR378D1 Gene

ORGUL Member Location for MIR378D1 gene

Proteins for MIR378D1 Gene

Post-translational modifications for MIR378D1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378D1 Gene

Domains & Families for MIR378D1 Gene

Gene Families for MIR378D1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378D1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378D1 Gene

Function for MIR378D1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378D1 Gene

Localization for MIR378D1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378D1 Gene

Pathways & Interactions for MIR378D1 Gene

SuperPathways for MIR378D1 Gene

No Data Available

Interacting Proteins for MIR378D1 Gene

Gene Ontology (GO) - Biological Process for MIR378D1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR378D1 Gene

Transcripts for MIR378D1 Gene

mRNA/cDNA for MIR378D1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378D1 Gene

No ASD Table

Relevant External Links for MIR378D1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR378D1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378D1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR378D1 Gene

Orthologs for MIR378D1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR378D1 Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 47 (a)
Species where no ortholog for MIR378D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR378D1 Gene

Gene Tree for MIR378D1 (if available)
Gene Tree for MIR378D1 (if available)

Paralogs for MIR378D1 Gene

No data available for Paralogs for MIR378D1 Gene

Variants for MIR378D1 Gene

Sequence variations from dbSNP and Humsavar for MIR378D1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1075684 -- 5,923,031(+) TCTCC(C/T)TGGGA intron-variant, downstream-variant-500B
rs113550598 -- 5,924,147(+) GGCTT(C/T)CTGGC intron-variant, upstream-variant-2KB
rs114452584 -- 5,923,090(+) GACGC(A/G)ATTTT intron-variant, downstream-variant-500B
rs114515593 -- 5,925,233(+) CGCTC(A/G)GCAAG intron-variant, upstream-variant-2KB
rs115441183 -- 5,925,295(+) CTAGT(A/G)GGGAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR378D1 Gene

Variant ID Type Subtype PubMed ID
esv34196 OTHER inversion 12058347
nsv525088 CNV loss 19592680
nsv829844 CNV gain 17160897
nsv829845 CNV loss 17160897

Relevant External Links for MIR378D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378D1 Gene

Disorders for MIR378D1 Gene

Relevant External Links for MIR378D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR378D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378D1 Gene

Publications for MIR378D1 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR378D1 Gene

Sources for MIR378D1 Gene

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