Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR378C Gene

Subcategory (RNA class) for MIR378C Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR378C Gene

  • MicroRNA 378c 2 3
  • Hsa-Mir-378c 3

External Ids for MIR378C Gene

Previous GeneCards Identifiers for MIR378C Gene

  • GC10U901430
  • GC10M132760

Summaries for MIR378C Gene

Entrez Gene Summary for MIR378C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378C Gene

MIR378C (MicroRNA 378c) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378C Gene

Genomics for MIR378C Gene

Genomic Location for MIR378C Gene

Start:
130,962,588 bp from pter
End:
130,962,668 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR378C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR378C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378C Gene

No data available for Regulatory Elements for MIR378C Gene

Proteins for MIR378C Gene

Post-translational modifications for MIR378C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378C Gene

Domains for MIR378C Gene

Gene Families for MIR378C Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378C Gene

Function for MIR378C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR378C Gene

Localization for MIR378C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378C Gene

Pathways for MIR378C Gene

SuperPathways for MIR378C Gene

No Data Available

Interacting Proteins for MIR378C Gene

Gene Ontology (GO) - Biological Process for MIR378C Gene

None

No data available for Pathways by source for MIR378C Gene

Transcripts for MIR378C Gene

mRNA/cDNA for MIR378C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378C Gene

No ASD Table

Relevant External Links for MIR378C Gene

GeneLoc Exon Structure for
MIR378C
ECgene alternative splicing isoforms for
MIR378C

Expression for MIR378C Gene

mRNA expression in normal human tissues for MIR378C Gene

genes like me logo Genes that share expressions with MIR378C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR378C Gene

Orthologs for MIR378C Gene

Evolution for MIR378C Gene

ENSEMBL:
Gene Tree for MIR378C (if available)
TreeFam:
Gene Tree for MIR378C (if available)

No data available for Orthologs for MIR378C Gene

Paralogs for MIR378C Gene

No data available for Paralogs for MIR378C Gene

Variants for MIR378C Gene

Sequence variations from dbSNP and Humsavar for MIR378C Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs892325 -- 130,963,379(+) TCGGC(A/G)GGGCG upstream-variant-2KB
rs2397741 -- 130,963,758(+) TTACC(A/G)AAGGC upstream-variant-2KB
rs7096489 -- 130,962,856(+) AAGCA(C/G)AGCTG upstream-variant-2KB
rs7912778 -- 130,963,442(+) ggaga(C/T)ggaga upstream-variant-2KB
rs11017616 -- 130,962,690(+) ATTCC(C/G)TGGGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR378C Gene

Variant ID Type Subtype PubMed ID
nsv428242 CNV Gain 18775914

Relevant External Links for MIR378C Gene

HapMap Linkage Disequilibrium report
MIR378C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR378C Gene

Disorders for MIR378C Gene

No disorders were found for MIR378C Gene.

No data available for UniProtKB/Swiss-Prot for MIR378C Gene

Publications for MIR378C Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR378C Gene

Sources for MIR378C Gene

Back to Top

Content