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Aliases for MIR378B Gene

Subcategory (RNA class) for MIR378B Gene


Quality Score for this RNA gene is


Aliases for MIR378B Gene

  • MicroRNA 378b 2 3
  • Hsa-Mir-378b 3

External Ids for MIR378B Gene

Previous GeneCards Identifiers for MIR378B Gene

  • GC03U901630
  • GC03P010371

Summaries for MIR378B Gene

Entrez Gene Summary for MIR378B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378B Gene

MIR378B (MicroRNA 378b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378B Gene

Genomics for MIR378B Gene

Genomic Location for MIR378B Gene

10,330,192 bp from pter
10,330,300 bp from pter
109 bases
Plus strand

Genomic View for MIR378B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR378B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378B Gene

No data available for Regulatory Elements for MIR378B Gene

Proteins for MIR378B Gene

Post-translational modifications for MIR378B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378B Gene

Domains for MIR378B Gene

Gene Families for MIR378B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378B Gene

Function for MIR378B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378B Gene

Localization for MIR378B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR378B Gene

Pathways for MIR378B Gene

SuperPathways for MIR378B Gene

No Data Available

Interacting Proteins for MIR378B Gene

Gene Ontology (GO) - Biological Process for MIR378B Gene


No data available for Pathways by source for MIR378B Gene

Transcripts for MIR378B Gene

mRNA/cDNA for MIR378B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378B Gene

No ASD Table

Relevant External Links for MIR378B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR378B Gene

mRNA expression in normal human tissues for MIR378B Gene

genes like me logo Genes that share expressions with MIR378B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR378B Gene

Orthologs for MIR378B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR378B Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 51 (a)
(Pan troglodytes)
Mammalia ptr-mir-378b 36
  • 100 (a)
Species with no ortholog for MIR378B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR378B Gene

Gene Tree for MIR378B (if available)
Gene Tree for MIR378B (if available)

Paralogs for MIR378B Gene

No data available for Paralogs for MIR378B Gene

Variants for MIR378B Gene

Relevant External Links for MIR378B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR378B Gene

Disorders for MIR378B Gene

No disorders were found for MIR378B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR378B Gene

Publications for MIR378B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3

Products for MIR378B Gene

Sources for MIR378B Gene

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