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Aliases for MIR376C Gene

Subcategory (RNA class) for MIR376C Gene


Quality Score for this RNA gene is


Aliases for MIR376C Gene

  • MicroRNA 376c 2 3
  • MicroRNA 368 2 3
  • Hsa-Mir-376c 3
  • Hsa-Mir-368 3
  • MiRNA368 3
  • Mir-376c 3
  • MIRN376C 3
  • MIRN368 3
  • MIR368 3

External Ids for MIR376C Gene

ORGUL Members for MIR376C Gene

Previous HGNC Symbols for MIR376C Gene

  • MIRN368
  • MIRN376C

Previous GeneCards Identifiers for MIR376C Gene

  • GC14P100802
  • GC14P100897
  • GC14P101507
  • GC14P101538
  • GC14P101571
  • GC14P101613
  • GC14P101641
  • GC14P101673
  • GC14P101706
  • GC14P101747
  • GC14P101812
  • GC14P101952
  • GC14P102143
  • GC14P101248

Summaries for MIR376C Gene

Entrez Gene Summary for MIR376C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR376C Gene

MIR376C (MicroRNA 376c) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR376C Gene

Genomics for MIR376C Gene

Genomic Location for MIR376C Gene

101,039,662 bp from pter
101,039,771 bp from pter
110 bases
Plus strand

Genomic View for MIR376C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR376C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR376C Gene

No data available for Regulatory Elements for MIR376C Gene

Proteins for MIR376C Gene

Post-translational modifications for MIR376C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR376C Gene

Domains & Families for MIR376C Gene

Gene Families for MIR376C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR376C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR376C Gene

Function for MIR376C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR376C Gene

Localization for MIR376C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR376C Gene

Pathways & Interactions for MIR376C Gene

SuperPathways for MIR376C Gene

No Data Available

Interacting Proteins for MIR376C Gene

Gene Ontology (GO) - Biological Process for MIR376C Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR376C Gene

Drugs & Compounds for MIR376C Gene

No Compound Related Data Available

Transcripts for MIR376C Gene

mRNA/cDNA for MIR376C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR376C Gene

No ASD Table

Relevant External Links for MIR376C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR376C Gene

mRNA expression in normal human tissues for MIR376C Gene

genes like me logo Genes that share expression patterns with MIR376C: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR376C Gene

Orthologs for MIR376C Gene

Evolution for MIR376C Gene

Gene Tree for MIR376C (if available)
Gene Tree for MIR376C (if available)

No data available for Orthologs for MIR376C Gene

Paralogs for MIR376C Gene

No data available for Paralogs for MIR376C Gene

Variants for MIR376C Gene

Sequence variations from dbSNP and Humsavar for MIR376C Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs74479777 -- 101,037,784(+) TGTTA(C/T)CTGGT upstream-variant-2KB
rs75418135 -- 101,037,959(+) GCATA(C/T)GCTTT upstream-variant-2KB
rs138277391 -- 101,038,034(+) TGGCA(C/T)CCTTG upstream-variant-2KB
rs141148232 -- 101,037,790(+) CTGGT(C/T)CACTC upstream-variant-2KB
rs141331899 -- 101,037,868(+) CAAGA(-/C)TTTTT upstream-variant-2KB

Relevant External Links for MIR376C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR376C Gene

Disorders for MIR376C Gene

Relevant External Links for MIR376C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR376C: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR376C Gene

Publications for MIR376C Gene

  1. Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines. (PMID: 26163549) Wijayakumara D.D. … Mackenzie P.I. (J. Pharmacol. Exp. Ther. 2015) 67
  2. miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer. (PMID: 25228385) Tan X. … Fu S.W. (Breast Cancer Res. 2014) 67
  3. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. (PMID: 24166498) Formosa A. … Candi E. (Oncogene 2014) 67
  4. A reciprocal antagonism between miR-376c and TGF-I^ signaling regulates neural differentiation of human pluripotent stem cells. (PMID: 25114173) Liu J. … Pan G. (FASEB J. 2014) 67
  5. MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line. (PMID: 23922722) Iwaki J. … Takizawa T. (PLoS ONE 2013) 67

Products for MIR376C Gene

Sources for MIR376C Gene

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