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Aliases for MIR376B Gene

Subcategory (RNA class) for MIR376B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR376B Gene

  • MicroRNA 376b 2 3
  • MIRN376B 3 6
  • Hsa-Mir-376b 3

External Ids for MIR376B Gene

ORGUL Members for MIR376B Gene

Previous HGNC Symbols for MIR376B Gene

  • MIRN376B

Previous GeneCards Identifiers for MIR376B Gene

  • GC14P100805
  • GC14P100899
  • GC14P101509
  • GC14P101565
  • GC14P101598
  • GC14P081690
  • GC14P101664
  • GC14P101699
  • GC14P101736
  • GC14P101776
  • GC14P101834
  • GC14P101974
  • GC14P102171

Summaries for MIR376B Gene

Entrez Gene Summary for MIR376B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR376B Gene

MIR376B (MicroRNA 376b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR376B Gene

Genomics for MIR376B Gene

Genomic Location for MIR376B Gene

Start:
101,040,427 bp from pter
End:
101,040,536 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR376B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR376B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR376B Gene

No data available for Regulatory Elements for MIR376B Gene

Proteins for MIR376B Gene

Post-translational modifications for MIR376B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR376B Gene

Domains for MIR376B Gene

Gene Families for MIR376B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR376B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR376B Gene

Function for MIR376B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR376B Gene

Localization for MIR376B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR376B Gene

Pathways for MIR376B Gene

SuperPathways for MIR376B Gene

No Data Available

Interacting Proteins for MIR376B Gene

Gene Ontology (GO) - Biological Process for MIR376B Gene

None

No data available for Pathways by source for MIR376B Gene

Transcripts for MIR376B Gene

mRNA/cDNA for MIR376B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR376B Gene

No ASD Table

Relevant External Links for MIR376B Gene

GeneLoc Exon Structure for
MIR376B
ECgene alternative splicing isoforms for
MIR376B

Expression for MIR376B Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR376B Gene

Orthologs for MIR376B Gene

Evolution for MIR376B Gene

ENSEMBL:
Gene Tree for MIR376B (if available)
TreeFam:
Gene Tree for MIR376B (if available)

No data available for Orthologs for MIR376B Gene

Paralogs for MIR376B Gene

No data available for Paralogs for MIR376B Gene

Variants for MIR376B Gene

Relevant External Links for MIR376B Gene

HapMap Linkage Disequilibrium report
MIR376B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR376B Gene

Disorders for MIR376B Gene

No disorders were found for MIR376B Gene.

No data available for UniProtKB/Swiss-Prot for MIR376B Gene

Publications for MIR376B Gene

  1. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. (PMID: 17322061) Kawahara Y. … Nishikura K. (Science 2007) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. (PMID: 22248718) Korkmaz G. … Gozuacik D. (Autophagy 2012) 3

Products for MIR376B Gene

Sources for MIR376B Gene

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