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Aliases for MIR376A1 Gene

Subcategory (RNA class) for MIR376A1 Gene


Quality Score for this RNA gene is


Aliases for MIR376A1 Gene

  • MicroRNA 376a-1 2 3 5
  • Hsa-Mir-376a-1 3
  • MicroRNA 376a 2
  • Hsa-Mir-376a 3
  • MIRN376A-1 3
  • Mir-376a-1 3
  • MIR376A-1 3
  • MIRN376A1 3
  • MIRN376A 3

External Ids for MIR376A1 Gene

ORGUL Members for MIR376A1 Gene

Previous HGNC Symbols for MIR376A1 Gene

  • MIRN376A
  • MIRN376A1

Previous GeneCards Identifiers for MIR376A1 Gene

  • GC14P100806
  • GC14P100900
  • GC14P101510
  • GC14P101566
  • GC14P101599
  • GC14P101637
  • GC14P101665
  • GC14P101700
  • GC14P101737
  • GC14P101777
  • GC14P101835
  • GC14P101975
  • GC14P102173
  • GC14P101251
  • GC14P101858
  • GC14P102110
  • GC14P102347

Summaries for MIR376A1 Gene

Entrez Gene Summary for MIR376A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR376A1 Gene

MIR376A1 (MicroRNA 376a-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR376A1 Gene

Genomics for MIR376A1 Gene

Genomic Location for MIR376A1 Gene

101,040,782 bp from pter
101,040,849 bp from pter
68 bases
Plus strand

Genomic View for MIR376A1 Gene

Genes around MIR376A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR376A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR376A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR376A1 Gene

No data available for Regulatory Elements for MIR376A1 Gene

Proteins for MIR376A1 Gene

Post-translational modifications for MIR376A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR376A1 Gene

Domains & Families for MIR376A1 Gene

Gene Families for MIR376A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR376A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR376A1 Gene

Function for MIR376A1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR376A1 Gene

Localization for MIR376A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR376A1 Gene

Pathways & Interactions for MIR376A1 Gene

SuperPathways for MIR376A1 Gene

No Data Available

Interacting Proteins for MIR376A1 Gene

Gene Ontology (GO) - Biological Process for MIR376A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR376A1 Gene

Transcripts for MIR376A1 Gene

mRNA/cDNA for MIR376A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR376A1 Gene

No ASD Table

Relevant External Links for MIR376A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR376A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR376A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR376A1 Gene:

genes like me logo Genes that share expression patterns with MIR376A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR376A1 Gene

Orthologs for MIR376A1 Gene

Evolution for MIR376A1 Gene

Gene Tree for MIR376A1 (if available)
Gene Tree for MIR376A1 (if available)

No data available for Orthologs for MIR376A1 Gene

Paralogs for MIR376A1 Gene

No data available for Paralogs for MIR376A1 Gene

Variants for MIR376A1 Gene

Sequence variations from dbSNP and Humsavar for MIR376A1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs112009054 -- 101,040,731(+) TCTGA(C/T)GACTC downstream-variant-500B, upstream-variant-2KB
rs112142802 -- 101,038,879(+) CTCCA(G/T)CCCAC upstream-variant-2KB
rs112745626 -- 101,041,204(+) GGGCT(A/G)TGGAA downstream-variant-500B, upstream-variant-2KB
rs114035552 -- 101,039,996(+) GCTCT(C/T)CTCTG downstream-variant-500B, upstream-variant-2KB
rs115462182 -- 101,038,950(+) AGGAA(A/C)CTGAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR376A1 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Relevant External Links for MIR376A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR376A1 Gene

Disorders for MIR376A1 Gene

Relevant External Links for MIR376A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR376A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR376A1 Gene

Publications for MIR376A1 Gene

  1. MiR-376a and histone deacetylation 9 form a regulatory circuitry in hepatocellular carcinoma. (PMID: 25613642) Zheng Y. … Ding B. (Cell. Physiol. Biochem. 2015) 3 64
  2. Early second-trimester serum microRNAs as potential biomarker for nondiabetic macrosomia. (PMID: 25405200) Hu L. … Jiang H. (Biomed Res Int 2014) 3 64
  3. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. (PMID: 24166498) Formosa A. … Candi E. (Oncogene 2014) 3 64
  4. A MicroRNA cluster at 14q32 drives aggressive lung adenocarcinoma. (PMID: 24833665) Nadal E. … Chen G. (Clin. Cancer Res. 2014) 3 64
  5. Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a. (PMID: 23373993) Zhang Y. … He B. (Neoplasma 2013) 3 64

Products for MIR376A1 Gene

Sources for MIR376A1 Gene

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