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Aliases for MIR374B Gene

Subcategory (RNA class) for MIR374B Gene


Quality Score for this RNA gene is


Aliases for MIR374B Gene

  • MicroRNA 374b 2 3
  • Hsa-Mir-374b 3
  • MIRN374B 3

External Ids for MIR374B Gene

Previous HGNC Symbols for MIR374B Gene

  • MIRN374B

Previous GeneCards Identifiers for MIR374B Gene

  • GC0XM073359
  • GC0XM073439
  • GC0XM073440
  • GC0XM073443
  • GC0XM073446

Summaries for MIR374B Gene

Entrez Gene Summary for MIR374B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR374B Gene

MIR374B (MicroRNA 374b) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR374B Gene

Genomics for MIR374B Gene

Genomic Location for MIR374B Gene

74,218,517 bp from pter
74,218,628 bp from pter
112 bases
Minus strand

Genomic View for MIR374B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR374B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR374B Gene

No data available for Regulatory Elements for MIR374B Gene

Proteins for MIR374B Gene

Post-translational modifications for MIR374B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR374B Gene

Domains for MIR374B Gene

Gene Families for MIR374B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR374B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR374B Gene

Function for MIR374B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR374B Gene

Localization for MIR374B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR374B Gene

Pathways for MIR374B Gene

SuperPathways for MIR374B Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR374B: view

Pathways by source for MIR374B Gene

1 BioSystems pathway for MIR374B Gene

Interacting Proteins for MIR374B Gene

Gene Ontology (GO) - Biological Process for MIR374B Gene


Transcripts for MIR374B Gene

mRNA/cDNA for MIR374B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR374B Gene

No ASD Table

Relevant External Links for MIR374B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR374B Gene

mRNA expression in normal human tissues for MIR374B Gene

genes like me logo Genes that share expressions with MIR374B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR374B Gene

Orthologs for MIR374B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR374B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-374b 36
  • 73 (a)
(Canis familiaris)
Mammalia cfa-mir-374b 36
  • 98 (a)
(Mus musculus)
Mammalia Mir374 36
  • 71 (a)
(Pan troglodytes)
Mammalia ptr-mir-374b 36
  • 100 (a)
Species with no ortholog for MIR374B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR374B Gene

Gene Tree for MIR374B (if available)
Gene Tree for MIR374B (if available)

Paralogs for MIR374B Gene

No data available for Paralogs for MIR374B Gene

Variants for MIR374B Gene

Relevant External Links for MIR374B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR374B Gene

Disorders for MIR374B Gene

No disorders were found for MIR374B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR374B Gene

Publications for MIR374B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3
  5. Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer. (PMID: 23405235) Cascione L. … Huebner K. (PLoS ONE 2013) 3

Products for MIR374B Gene

Sources for MIR374B Gene

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