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Aliases for MIR371B Gene

Subcategory (RNA class) for MIR371B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR371B Gene

  • MicroRNA 371b 2 3 5
  • Hsa-Mir-371b 3

External Ids for MIR371B Gene

Previous GeneCards Identifiers for MIR371B Gene

  • GC19U901536
  • GC19M054294

Summaries for MIR371B Gene

Entrez Gene Summary for MIR371B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR371B Gene

MIR371B (MicroRNA 371b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR371B Gene

Genomics for MIR371B Gene

Regulatory Elements for MIR371B Gene

Enhancers for MIR371B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F053787 0.6 FANTOM5 0.8 +0.2 225 0.0 TBP CBX3 NRF1 ZBTB11 GTF2A2 ZBTB40 TRIM24 CREM MGA BIRC8 ZNF765 ZNF813 ZNF761 ZNF845 GC19P053843 MIR371B
GH19F053788 1 FANTOM5 0.8 -0.5 -482 0.2 NLRP12 DPRX ZNF331 GC19P053885 MIR371B
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR371B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR371B Gene

Chromosome:
19
Start:
53,787,597 bp from pter
End:
53,788,169 bp from pter
Size:
573 bases
Orientation:
Minus strand

Genomic View for MIR371B Gene

Genes around MIR371B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR371B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR371B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR371B Gene

Proteins for MIR371B Gene

Post-translational modifications for MIR371B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR371B Gene

Domains & Families for MIR371B Gene

Gene Families for MIR371B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR371B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR371B Gene

Function for MIR371B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR371B Gene

Localization for MIR371B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR371B Gene

Pathways & Interactions for MIR371B Gene

SuperPathways for MIR371B Gene

No Data Available

Interacting Proteins for MIR371B Gene

Gene Ontology (GO) - Biological Process for MIR371B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR371B Gene

Transcripts for MIR371B Gene

mRNA/cDNA for MIR371B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR371B Gene

No ASD Table

Relevant External Links for MIR371B Gene

GeneLoc Exon Structure for
MIR371B
ECgene alternative splicing isoforms for
MIR371B

Expression for MIR371B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR371B Gene

mRNA differential expression in normal tissues according to GTEx for MIR371B Gene

This gene is overexpressed in Whole Blood (x36.8) and Testis (x12.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR371B Gene:

MIR371B
genes like me logo Genes that share expression patterns with MIR371B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR371B Gene

Orthologs for MIR371B Gene

Evolution for MIR371B Gene

ENSEMBL:
Gene Tree for MIR371B (if available)
TreeFam:
Gene Tree for MIR371B (if available)

No data available for Orthologs for MIR371B Gene

Paralogs for MIR371B Gene

No data available for Paralogs for MIR371B Gene

Variants for MIR371B Gene

Sequence variations from dbSNP and Humsavar for MIR371B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10425222 -- 53,788,945(+) GTTCA(A/C)CTGCA downstream-variant-500B, upstream-variant-2KB
rs11084296 -- 53,787,231(+) TTTTT(A/G)GGAGA downstream-variant-500B, upstream-variant-2KB
rs11084297 -- 53,787,405(+) CGAAG(G/T)CCCCA downstream-variant-500B, upstream-variant-2KB
rs111707564 -- 53,787,614(+) AAAAG(C/T)CTCTT downstream-variant-500B, upstream-variant-2KB
rs111870215 -- 53,789,227(+) CAGGC(A/G)TGAGC downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR371B Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV deletion 23290073
nsv1058969 CNV gain 25217958
nsv1064558 CNV gain 25217958
nsv458781 CNV gain 19166990
nsv580108 CNV gain 21841781

Relevant External Links for MIR371B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR371B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR371B Gene

Disorders for MIR371B Gene

Relevant External Links for MIR371B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR371B

No disorders were found for MIR371B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR371B Gene

Publications for MIR371B Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR371B Gene

Sources for MIR371B Gene

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