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Aliases for MIR371A Gene

Subcategory (RNA class) for MIR371A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR371A Gene

  • MicroRNA 371a 2 3
  • MicroRNA 371 2 3
  • MIRN371 3 6
  • MIR371 3 6
  • Hsa-Mir-371a 3
  • Hsa-Mir-371 3

External Ids for MIR371A Gene

ORGUL Members for MIR371A Gene

Previous HGNC Symbols for MIR371A Gene

  • MIRN371
  • MIR371

Previous GeneCards Identifiers for MIR371A Gene

  • GC19P054307
  • GC19P054333
  • GC19P054354
  • GC19P054431
  • GC19P054509

Summaries for MIR371A Gene

Entrez Gene Summary for MIR371A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR371A Gene

MIR371A (MicroRNA 371a) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR371A include testicular germ cell tumor. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR371A Gene

Genomics for MIR371A Gene

Genomic Location for MIR371A Gene

Start:
53,787,675 bp from pter
End:
53,787,741 bp from pter
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR371A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR371A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR371A Gene

No data available for Regulatory Elements for MIR371A Gene

Proteins for MIR371A Gene

Post-translational modifications for MIR371A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR371A Gene

Domains for MIR371A Gene

Gene Families for MIR371A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR371A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR371A Gene

Function for MIR371A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR371A Gene

Localization for MIR371A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR371A Gene

Pathways for MIR371A Gene

SuperPathways for MIR371A Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR371A: view

Pathways by source for MIR371A Gene

1 BioSystems pathway for MIR371A Gene

Interacting Proteins for MIR371A Gene

Gene Ontology (GO) - Biological Process for MIR371A Gene

None

Transcripts for MIR371A Gene

mRNA/cDNA for MIR371A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR371A Gene

No ASD Table

Relevant External Links for MIR371A Gene

GeneLoc Exon Structure for
MIR371A
ECgene alternative splicing isoforms for
MIR371A

Expression for MIR371A Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR371A Gene

Orthologs for MIR371A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR371A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-371 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-371 36
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-371 36
  • 67 (a)
OneToMany
cfa-mir-371 36
  • 67 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Mir290 36
  • 57 (a)
OneToMany
Mir291b 36
  • 54 (a)
OneToMany
Mir292 36
  • 56 (a)
OneToMany
Mir293 36
  • 59 (a)
OneToMany
Mir294 36
  • 49 (a)
OneToMany
Mir295 36
  • 68 (a)
OneToMany
chicken
(Gallus gallus)
Aves gga-mir-219b 36
  • 26 (a)
OneToMany
Species with no ortholog for MIR371A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR371A Gene

ENSEMBL:
Gene Tree for MIR371A (if available)
TreeFam:
Gene Tree for MIR371A (if available)

Paralogs for MIR371A Gene

No data available for Paralogs for MIR371A Gene

Variants for MIR371A Gene

Sequence variations from dbSNP and Humsavar for MIR371A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs6509815 -- 53,785,877(+) ttttc(C/T)tttct upstream-variant-2KB
rs6509816 -- 53,785,884(+) ttctc(C/T)ctctc upstream-variant-2KB
rs56658217 -- 53,785,851(+) AAAAA(-/A)TGTTC upstream-variant-2KB
rs139352376 -- 53,785,759(+) GAGTT(C/T)CTCTC upstream-variant-2KB
rs190936182 -- 53,785,874(+) TTTTT(C/T)TCTTT upstream-variant-2KB

Relevant External Links for MIR371A Gene

HapMap Linkage Disequilibrium report
MIR371A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR371A Gene

Disorders for MIR371A Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR371A Gene including...

Search for MIR371A Gene in MalaCards »
genes like me logo Genes that share disorders with MIR371A: view

No data available for UniProtKB/Swiss-Prot for MIR371A Gene

Publications for MIR371A Gene

  1. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. (PMID: 17695719) Voorhoeve P.M. … Agami R. (Adv. Exp. Med. Biol. 2007) 3
  5. The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas. (PMID: 20209130) Rippe V. … Bullerdiek J. (PLoS ONE 2010) 3

Products for MIR371A Gene

Sources for MIR371A Gene

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