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Aliases for MIR371A Gene

Subcategory (RNA class) for MIR371A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR371A Gene

  • MicroRNA 371a 2 3 5
  • MicroRNA 371 2 3
  • Hsa-Mir-371a 3
  • Hsa-Mir-371 3
  • MIRN371 3
  • MIR371 3

External Ids for MIR371A Gene

ORGUL Members for MIR371A Gene

Previous HGNC Symbols for MIR371A Gene

  • MIRN371
  • MIR371

Previous GeneCards Identifiers for MIR371A Gene

  • GC19P054307
  • GC19P054333
  • GC19P054354
  • GC19P054431
  • GC19P054509

Summaries for MIR371A Gene

Entrez Gene Summary for MIR371A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR371A Gene

MIR371A (MicroRNA 371a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR371A Gene

Genomics for MIR371A Gene

Genomic Location for MIR371A Gene

Chromosome:
19
Start:
53,787,675 bp from pter
End:
53,787,741 bp from pter
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR371A Gene

Genes around MIR371A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR371A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR371A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR371A Gene

No data available for Regulatory Elements for MIR371A Gene

Proteins for MIR371A Gene

Post-translational modifications for MIR371A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR371A Gene

Domains & Families for MIR371A Gene

Gene Families for MIR371A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR371A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR371A Gene

Function for MIR371A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR371A Gene

Localization for MIR371A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR371A Gene

Pathways & Interactions for MIR371A Gene

SuperPathways for MIR371A Gene

SuperPathway Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR371A: view

Pathways by source for MIR371A Gene

1 BioSystems pathway for MIR371A Gene

Interacting Proteins for MIR371A Gene

Gene Ontology (GO) - Biological Process for MIR371A Gene

None

No data available for SIGNOR curated interactions for MIR371A Gene

Transcripts for MIR371A Gene

mRNA/cDNA for MIR371A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR371A Gene

No ASD Table

Relevant External Links for MIR371A Gene

GeneLoc Exon Structure for
MIR371A
ECgene alternative splicing isoforms for
MIR371A

Expression for MIR371A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR371A Gene:

MIR371A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR371A Gene

Orthologs for MIR371A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR371A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-371 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-371 35
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir295 35
  • 68 (a)
OneToMany
Mir293 35
  • 59 (a)
OneToMany
Mir290 35
  • 57 (a)
OneToMany
Mir292 35
  • 56 (a)
OneToMany
Mir291b 35
  • 54 (a)
OneToMany
Mir294 35
  • 49 (a)
OneToMany
dog
(Canis familiaris)
Mammalia cfa-mir-371 35 35
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves gga-mir-219b 35
  • 26 (a)
OneToMany
Species where no ortholog for MIR371A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR371A Gene

ENSEMBL:
Gene Tree for MIR371A (if available)
TreeFam:
Gene Tree for MIR371A (if available)

Paralogs for MIR371A Gene

No data available for Paralogs for MIR371A Gene

Variants for MIR371A Gene

Sequence variations from dbSNP and Humsavar for MIR371A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs11084295 -- 53,786,224(+) accac(A/G)ccgag upstream-variant-2KB
rs11084296 -- 53,787,231(+) TTTTT(A/G)GGAGA downstream-variant-500B, upstream-variant-2KB
rs11084297 -- 53,787,405(+) CGAAG(G/T)CCCCA downstream-variant-500B, upstream-variant-2KB
rs111707564 -- 53,787,614(+) AAAAG(C/T)CTCTT downstream-variant-500B, upstream-variant-2KB
rs112811521 -- 53,786,062(+) TTTTT(A/T)AAAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR371A Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV deletion 23290073
nsv1058969 CNV gain 25217958
nsv1064558 CNV gain 25217958
nsv458781 CNV gain 19166990
nsv580108 CNV gain 21841781

Relevant External Links for MIR371A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR371A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR371A Gene

Disorders for MIR371A Gene

Relevant External Links for MIR371A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR371A

No disorders were found for MIR371A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR371A Gene

Publications for MIR371A Gene

  1. A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. (PMID: 26671749) Murray M.J. … Coleman N. (Br. J. Cancer 2016) 3 64
  2. MicroRNA miR-371a-3p in serum of patients with germ cell tumours: evaluations for establishing a serum biomarker. (PMID: 25187505) Spiekermann M. … Dieckmann K.P. (Andrology 2015) 3 64
  3. The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer. (PMID: 25868860) Li Y. … Liang L. (Oncotarget 2015) 3 64
  4. MiR-371-5p facilitates pancreatic cancer cell proliferation and decreases patient survival. (PMID: 25411783) He D. … Zhang Z. (PLoS ONE 2014) 3 64
  5. miR-371-5p down-regulates pre mRNA processing factor 4 homolog B (PRPF4B) and facilitates the G1/S transition in human hepatocellular carcinoma cells. (PMID: 23466643) Liu R.Y. … Tang H. (Cancer Lett. 2013) 3 64

Products for MIR371A Gene

Sources for MIR371A Gene

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