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Aliases for MIR370 Gene

Subcategory (RNA class) for MIR370 Gene


Quality Score for this RNA gene is


Aliases for MIR370 Gene

  • MicroRNA 370 2 3
  • MIRN370 3 6
  • Hsa-Mir-370 3

External Ids for MIR370 Gene

ORGUL Members for MIR370 Gene

Previous HGNC Symbols for MIR370 Gene

  • MIRN370

Previous GeneCards Identifiers for MIR370 Gene

  • GC14P100468
  • GC14P100850
  • GC14P101377

Summaries for MIR370 Gene

Entrez Gene Summary for MIR370 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR370 Gene

MIR370 (MicroRNA 370) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR370 Gene

Genomics for MIR370 Gene

Genomic Location for MIR370 Gene

100,911,138 bp from pter
100,911,217 bp from pter
80 bases
Plus strand

Genomic View for MIR370 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR370 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR370 Gene

No data available for Regulatory Elements for MIR370 Gene

Proteins for MIR370 Gene

Post-translational modifications for MIR370 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR370 Gene

Domains for MIR370 Gene

Gene Families for MIR370 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR370: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR370 Gene

Function for MIR370 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR370 Gene

Localization for MIR370 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR370 Gene

Pathways for MIR370 Gene

SuperPathways for MIR370 Gene

No Data Available

Interacting Proteins for MIR370 Gene

Gene Ontology (GO) - Biological Process for MIR370 Gene


No data available for Pathways by source for MIR370 Gene

Transcripts for MIR370 Gene

mRNA/cDNA for MIR370 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR370 Gene

No ASD Table

Relevant External Links for MIR370 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR370 Gene

mRNA expression in normal human tissues for MIR370 Gene

genes like me logo Genes that share expressions with MIR370: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR370 Gene

Orthologs for MIR370 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR370 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-370 36
  • 97 (a)
(Canis familiaris)
Mammalia cfa-mir-370 36
  • 92 (a)
(Mus musculus)
Mammalia Mir370 36
  • 90 (a)
(Pan troglodytes)
Mammalia ptr-mir-370 36
  • 100 (a)
Species with no ortholog for MIR370:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR370 Gene

Gene Tree for MIR370 (if available)
Gene Tree for MIR370 (if available)

Paralogs for MIR370 Gene

No data available for Paralogs for MIR370 Gene

Variants for MIR370 Gene

Relevant External Links for MIR370 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR370 Gene

Disorders for MIR370 Gene

Relevant External Links for MIR370

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for MIR370 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR370 Gene

Publications for MIR370 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. FoxM1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by miR-370. (PMID: 23576572) Feng Y. … Jia J. (Mol. Cancer Res. 2013) 3
  3. Upregulation of miR-370 contributes to the progression of gastric carcinoma via suppression of FOXO1. (PMID: 23721824) Fan C. … Zhang L. (Biomed. Pharmacother. 2013) 3
  4. MicroRNA-370 suppresses proliferation and promotes endometrioid ovarian cancer chemosensitivity to cDDP by negatively regulating ENG. (PMID: 25063739) Chen X.P. … Shen Z.J. (Cancer Lett. 2014) 3
  5. miR-370 targeted FoxM1 functions as a tumor suppressor in laryngeal squamous cell carcinoma (LSCC). (PMID: 24055400) Yungang W. … Pan X. (Biomed. Pharmacother. 2013) 3

Products for MIR370 Gene

Sources for MIR370 Gene

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