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Aliases for MIR3686 Gene

Subcategory (RNA class) for MIR3686 Gene


Quality Score for this RNA gene is


Aliases for MIR3686 Gene

  • MicroRNA 3686 2 3 5
  • Hsa-Mir-3686 3

External Ids for MIR3686 Gene

Previous GeneCards Identifiers for MIR3686 Gene

  • GC08U901497
  • GC08M130498

Summaries for MIR3686 Gene

Entrez Gene Summary for MIR3686 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3686 Gene

MIR3686 (MicroRNA 3686) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3686 Gene

Genomics for MIR3686 Gene

Regulatory Elements for MIR3686 Gene

Enhancers for MIR3686 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G129479 1 Ensembl ENCODE 0.7 +3.8 3845 1.6 BCOR CTCF PKNOX1 ATF1 BACH1 ZNF175 ZMYM3 ZNF316 NFE2 PRDM10 MIR3686 ENSG00000253926
GH08G129490 1.2 FANTOM5 ENCODE 0.4 -7.2 -7175 1.7 ATF1 ARNT SIN3A FEZF1 GLIS2 ZNF766 GATA2 FOS SP3 NCOA1 MIR3686 GC08P129559
GH08G129513 1.5 Ensembl ENCODE dbSUPER 0.3 -31.4 -31437 3.4 PKNOX1 SIN3A TCF12 GATA2 FOS DEK JUNB REST ZNF592 MBD2 MIR3686 GC08P129559
GH08G129489 0.9 FANTOM5 Ensembl 0.4 -5.4 -5350 0.6 SREBF1 CEBPB MAX SPI1 MIR3686 GC08P129559
GH08G129546 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.2 -63.6 -63640 3.4 TBP PKNOX1 TBL1XR1 WRNIP1 ZNF766 RELB ETV6 IKZF2 CREM CAVIN1 FAM49B GC08P129559 MIR3686
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3686 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3686 Gene

129,484,057 bp from pter
129,484,142 bp from pter
86 bases
Minus strand

Genomic View for MIR3686 Gene

Genes around MIR3686 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3686 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3686 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3686 Gene

ORGUL Member Location for MIR3686 Gene

ORGUL Member Location for MIR3686 gene

Proteins for MIR3686 Gene

Post-translational modifications for MIR3686 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3686 Gene

Domains & Families for MIR3686 Gene

Gene Families for MIR3686 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3686: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3686 Gene

Function for MIR3686 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3686 Gene

Localization for MIR3686 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3686 Gene

Pathways & Interactions for MIR3686 Gene

SuperPathways for MIR3686 Gene

No Data Available

Interacting Proteins for MIR3686 Gene

Gene Ontology (GO) - Biological Process for MIR3686 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3686 Gene

Drugs & Compounds for MIR3686 Gene

No Compound Related Data Available

Transcripts for MIR3686 Gene

mRNA/cDNA for MIR3686 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3686 Gene

No ASD Table

Relevant External Links for MIR3686 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3686 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3686 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3686 Gene

Orthologs for MIR3686 Gene

Evolution for MIR3686 Gene

Gene Tree for MIR3686 (if available)
Gene Tree for MIR3686 (if available)

No data available for Orthologs for MIR3686 Gene

Paralogs for MIR3686 Gene

No data available for Paralogs for MIR3686 Gene

Variants for MIR3686 Gene

Sequence variations from dbSNP and Humsavar for MIR3686 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001327690 -- 129,485,371(+) TATTT(-/TA)TATAT intron-variant, upstream-variant-2KB
rs1001675899 -- 129,485,530(+) CACAC(-/AT)ATGTA intron-variant, upstream-variant-2KB
rs1002649052 -- 129,485,197(+) TGGAA(C/T)AAATG intron-variant, upstream-variant-2KB
rs1004133615 -- 129,484,285(+) TGAAG(A/G)ACAGA intron-variant, upstream-variant-2KB
rs1004295777 -- 129,484,586(+) TCTTG(A/C)CTTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3686 Gene

Variant ID Type Subtype PubMed ID
nsv1015611 CNV gain 25217958

Relevant External Links for MIR3686 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3686 Gene

Disorders for MIR3686 Gene

Relevant External Links for MIR3686

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR3686 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3686 Gene

Publications for MIR3686 Gene

  1. The MicroRNA3686 Inhibits the Proliferation of Pancreas Carcinoma Cell Line by Targeting the Polo-Like Kinase 1. (PMID: 26090465) Jin H.Y. … Yang B. (Biomed Res Int 2015) 3 64
  2. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C. … Bhattacharya A. (BMC Genomics 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3686 Gene

Sources for MIR3686 Gene

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