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Aliases for MIR3680-1 Gene

Subcategory (RNA class) for MIR3680-1 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3680-1 Gene

  • MicroRNA 3680-1 2 3 5
  • MicroRNA 3680 2 3
  • Hsa-Mir-3680-1 3
  • Hsa-Mir-3680 3
  • MIR3680 3

External Ids for MIR3680-1 Gene

Previous HGNC Symbols for MIR3680-1 Gene

  • MIR3680

Previous GeneCards Identifiers for MIR3680-1 Gene

  • GC16U901352
  • GC16M021520

Summaries for MIR3680-1 Gene

Entrez Gene Summary for MIR3680-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3680-1 Gene

MIR3680-1 (MicroRNA 3680-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3680-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3680-1 Gene

Genomics for MIR3680-1 Gene

GeneHancer (GH) Regulatory Elements for MIR3680-1 Gene

Promoters and enhancers for MIR3680-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I021500 Promoter/Enhancer 1.6 Ensembl ENCODE 0.8 +4.1 4139 3.6 HDGF PKNOX1 CLOCK MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 ENSG00000260635 SMG1P1 SMG1P4 SMG1P3 C16orf52 THUMPD1 POLR3E REXO5 MFSD13B ENSG00000260306
GH16I021505 Enhancer 1.5 Ensembl ENCODE dbSUPER 0.8 -4.0 -4014 9.5 HDGF PKNOX1 CLOCK FOXA2 SMAD1 MLX ZFP64 ARID4B NEUROD1 SIN3A PIR32900 PIR56760 PIR45912 LOC105371129 REXO5 MFSD13B NPIPB5 ENSG00000260306 MIR3680-1 PIR36552
GH16I021486 Enhancer 0.2 Ensembl 0.4 +19.0 19034 0.6 MIR3680-1 SMG1P3 NPIPB3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3680-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3680-1 Gene

Genomic Locations for MIR3680-1 Gene
chr16:21,506,049-21,506,135
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand
chr16:21,517,370-21,517,456
(GRCh37/hg19)

Genomic View for MIR3680-1 Gene

Genes around MIR3680-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3680-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3680-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3680-1 Gene

ORGUL Member Location for MIR3680-1 Gene

ORGUL Member Location for MIR3680-1 gene

Proteins for MIR3680-1 Gene

Post-translational modifications for MIR3680-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3680-1 Gene

Domains & Families for MIR3680-1 Gene

Gene Families for MIR3680-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3680-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3680-1 Gene

Function for MIR3680-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3680-1 Gene

Localization for MIR3680-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3680-1 Gene

Pathways & Interactions for MIR3680-1 Gene

SuperPathways for MIR3680-1 Gene

No Data Available

Interacting Proteins for MIR3680-1 Gene

Gene Ontology (GO) - Biological Process for MIR3680-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3680-1 Gene

Drugs & Compounds for MIR3680-1 Gene

No Compound Related Data Available

Transcripts for MIR3680-1 Gene

mRNA/cDNA for MIR3680-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3680-1 Gene

No ASD Table

Relevant External Links for MIR3680-1 Gene

GeneLoc Exon Structure for
MIR3680-1
ECgene alternative splicing isoforms for
MIR3680-1

Expression for MIR3680-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3680-1 Gene

genes like me logo Genes that share expression patterns with MIR3680-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3680-1 Gene

Orthologs for MIR3680-1 Gene

Evolution for MIR3680-1 Gene

ENSEMBL:
Gene Tree for MIR3680-1 (if available)
TreeFam:
Gene Tree for MIR3680-1 (if available)

No data available for Orthologs for MIR3680-1 Gene

Paralogs for MIR3680-1 Gene

No data available for Paralogs for MIR3680-1 Gene

Variants for MIR3680-1 Gene

Sequence variations from dbSNP and Humsavar for MIR3680-1 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1001576913 -- 21,505,624(-) G/A downstream_transcript_variant
rs1008386816 -- 21,506,653(-) A/C upstream_transcript_variant
rs1008444038 -- 21,507,302(-) C/A upstream_transcript_variant
rs1011811314 -- 21,506,604(-) G/C upstream_transcript_variant
rs1012253980 -- 21,505,700(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3680-1 Gene

Variant ID Type Subtype PubMed ID
dgv1316n106 CNV duplication 24896259
dgv2800n100 CNV gain 25217958
dgv2801n100 CNV loss 25217958
esv2421840 CNV deletion 20811451
esv25717 CNV gain+loss 19812545
esv2758636 CNV gain+loss 17122850
esv2758641 CNV gain 17122850
esv2762010 CNV gain+loss 21179565
esv2763135 CNV gain 21179565
esv29892 CNV gain 19812545
esv32773 CNV loss 17666407
esv33799 CNV loss 17666407
esv34235 CNV gain 17911159
esv3584705 CNV loss 24956385
nsv1056249 CNV gain 25217958
nsv1076422 CNV duplication 25765185
nsv1152437 CNV duplication 26484159
nsv1160372 CNV duplication 26073780
nsv428322 CNV gain 18775914
nsv433437 CNV gain 18776910
nsv433438 CNV gain 18776910
nsv442716 CNV gain 18776908
nsv509606 CNV insertion 20534489
nsv827584 CNV gain 20364138
nsv9397 CNV gain+loss 18304495
nsv9429 CNV loss 18304495
nsv978108 CNV duplication 23825009
nsv978128 CNV duplication 23825009

Additional Variant Information for MIR3680-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3680-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3680-1 Gene

Disorders for MIR3680-1 Gene

Additional Disease Information for MIR3680-1

No disorders were found for MIR3680-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3680-1 Gene

Publications for MIR3680-1 Gene

  1. Differentially expressed miR-3680-5p is associated with parathyroid hormone regulation in peritoneal dialysis patients. (PMID: 28152049) Jeong S … Kim IW (PloS one 2017) 3 58
  2. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C … Bhattacharya A (BMC genomics 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3680-1 Gene

Sources for MIR3680-1 Gene

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