Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3674 Gene

Subcategory (RNA class) for MIR3674 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3674 Gene

  • MicroRNA 3674 2 3 5
  • Hsa-Mir-3674 3

External Ids for MIR3674 Gene

Previous GeneCards Identifiers for MIR3674 Gene

  • GC08U901489
  • GC08P001751
  • GC08P001756

Summaries for MIR3674 Gene

Entrez Gene Summary for MIR3674 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3674 Gene

MIR3674 (MicroRNA 3674) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3674 include Ceroid Lipofuscinosis, Neuronal, 8. Among its related pathways are Synaptic vesicle cycle.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3674 Gene

Genomics for MIR3674 Gene

Regulatory Elements for MIR3674 Gene

Enhancers for MIR3674 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G001799 1.3 Ensembl ENCODE dbSUPER 0.7 +0.6 616 4.5 HDAC1 HDGF BCOR TAL1 ZSCAN4 TSC22D4 ZMYM3 RBBP5 CDC5L TCF12 ENSG00000253982 CLN8 MIR3674 LOC105377779
GH08G001785 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -13.6 -13628 3.8 PKNOX1 TBL1XR1 ZNF2 RAD21 RFX5 GLIS2 EGR1 GATA2 ZNF366 ZNF143 ENSG00000253982 CLN8 MIR596 PIR39323 MIR3674
GH08G001813 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +13.0 13007 1.3 ZBTB40 ZNF335 TCF12 ETV6 EGR2 GATAD2B ZEB2 ZNF592 SMARCA4 ZNF341 KBTBD11 ARHGEF10 LOC105377779 MIR3674
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3674 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3674 Gene

Chromosome:
8
Start:
1,801,125 bp from pter
End:
1,801,192 bp from pter
Size:
68 bases
Orientation:
Plus strand

Genomic View for MIR3674 Gene

Genes around MIR3674 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3674 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3674 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3674 Gene

Proteins for MIR3674 Gene

Post-translational modifications for MIR3674 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3674 Gene

Domains & Families for MIR3674 Gene

Gene Families for MIR3674 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3674: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3674 Gene

Function for MIR3674 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3674 Gene

Localization for MIR3674 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3674 Gene

Pathways & Interactions for MIR3674 Gene

SuperPathways for MIR3674 Gene

SuperPathway Contained pathways
1 Synaptic vesicle cycle
genes like me logo Genes that share pathways with MIR3674: view

Pathways by source for MIR3674 Gene

1 BioSystems pathway for MIR3674 Gene

Interacting Proteins for MIR3674 Gene

Gene Ontology (GO) - Biological Process for MIR3674 Gene

None

No data available for SIGNOR curated interactions for MIR3674 Gene

Drugs & Compounds for MIR3674 Gene

No Compound Related Data Available

Transcripts for MIR3674 Gene

mRNA/cDNA for MIR3674 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3674 Gene

No ASD Table

Relevant External Links for MIR3674 Gene

GeneLoc Exon Structure for
MIR3674
ECgene alternative splicing isoforms for
MIR3674

Expression for MIR3674 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3674 Gene:

MIR3674
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3674 Gene

Orthologs for MIR3674 Gene

Evolution for MIR3674 Gene

ENSEMBL:
Gene Tree for MIR3674 (if available)
TreeFam:
Gene Tree for MIR3674 (if available)

No data available for Orthologs for MIR3674 Gene

Paralogs for MIR3674 Gene

No data available for Paralogs for MIR3674 Gene

Variants for MIR3674 Gene

Sequence variations from dbSNP and Humsavar for MIR3674 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000174618 -- 1,800,513(+) TATTT(A/C)CATGT upstream-variant-2KB
rs1000477976 -- 1,799,672(+) TCTGA(C/T)CTAAA upstream-variant-2KB
rs1000863668 -- 1,799,618(+) GGAAA(C/T)GGATG upstream-variant-2KB
rs1001276152 -- 1,799,509(+) CGGCC(C/T)CCCAA upstream-variant-2KB
rs1004291356 -- 1,799,777(+) TGTGA(C/T)AGACT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3674 Gene

Variant ID Type Subtype PubMed ID
dgv11822n54 CNV loss 21841781
dgv850n27 CNV loss 19166990
esv3576504 CNV gain 25503493
esv3615841 CNV loss 21293372
esv3615842 CNV gain 21293372
esv3615846 CNV loss 21293372
esv3891267 CNV gain 25118596
nsv1017597 CNV loss 25217958
nsv1024325 CNV gain 25217958
nsv1025591 CNV gain 25217958
nsv465277 CNV gain 19166990
nsv470167 CNV gain 18288195
nsv509244 CNV insertion 20534489
nsv609527 CNV loss 21841781
nsv609531 CNV gain 21841781
nsv609533 CNV gain 21841781
nsv824454 CNV gain 20364138

Relevant External Links for MIR3674 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3674

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3674 Gene

Disorders for MIR3674 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3674 Gene - From: GeneCards

Disorder Aliases PubMed IDs
ceroid lipofuscinosis, neuronal, 8
  • neuronal ceroid lipofuscinosis 8
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR3674

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3674
genes like me logo Genes that share disorders with MIR3674: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3674 Gene

Publications for MIR3674 Gene

  1. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C. … Bhattacharya A. (BMC Genomics 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3674 Gene

Sources for MIR3674 Gene

Content
Loading form....