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Aliases for MIR367 Gene

Subcategory (RNA class) for MIR367 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR367 Gene

  • MicroRNA 367 2 3 5
  • Hsa-Mir-367 3
  • MIRN367 3

External Ids for MIR367 Gene

Previous HGNC Symbols for MIR367 Gene

  • MIRN367

Previous GeneCards Identifiers for MIR367 Gene

  • GC04M113795
  • GC04M113569

Summaries for MIR367 Gene

Entrez Gene Summary for MIR367 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR367 Gene

MIR367 (MicroRNA 367) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR367 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR367

Additional gene information for MIR367 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR367 Gene

Genomics for MIR367 Gene

GeneHancer (GH) Regulatory Elements for MIR367 Gene

Promoters and enhancers for MIR367 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I112704 Promoter/Enhancer 1.6 Ensembl ENCODE dbSUPER 11.3 -58.1 -58095 2.9 PKNOX1 ZNF2 GLIS2 KLF7 SP3 REST ZNF610 GLIS1 SP7 KLF1 ENSG00000250046 LOC109864269 MIR302A MIR302C MIR302D MIR367 LARP7 RPL7AP30 ZGRF1 WRBP1
GH04I112746 Enhancer 0.8 ENCODE dbSUPER 11.1 -102.3 -102317 7.2 ETS1 SP1 GATA3 ZNF316 JUND POLR2A POU5F1 PRDM1 MAFK EZH2 ZGRF1 LARP7 MIR302A MIR302C MIR367 MIR302D LOC109864269 GC04M112739 ENSG00000202536 GC04M112756
GH04I112754 Enhancer 0.2 dbSUPER 11.1 -106.9 -106871 1.3 ENSG00000202536 GC04M112756 ZGRF1 LARP7 MIR302A MIR302C MIR302D MIR367 LOC109864269 GC04M112739
GH04I112645 Enhancer 1.1 FANTOM5 ENCODE dbSUPER 0.8 -3.1 -3077 11.2 PAF1 CTCF USF1 ZNF10 SIN3A ETS1 ZKSCAN1 SP1 NFIC POLR2A LOC109864269 LOC105377372 LARP7 ZGRF1 MIR302A MIR302B MIR302C MIR302D MIR367 GC04M112615
GH04I112636 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.4 +10.7 10745 2.9 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 YBX1 ZNF2 YY1 ZGRF1 LARP7 LOC105377372 LOC109864269 ENSG00000250966 MIR367 GC04M112615
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR367 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR367 Gene

Genomic Locations for MIR367 Gene
chr4:112,647,874-112,647,941
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand
chr4:113,569,030-113,569,097
(GRCh37/hg19)

Genomic View for MIR367 Gene

Genes around MIR367 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR367 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR367 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR367 Gene

ORGUL Member Location for MIR367 Gene

ORGUL Member Location for MIR367 gene

Proteins for MIR367 Gene

Post-translational modifications for MIR367 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR367 Gene

Domains & Families for MIR367 Gene

Gene Families for MIR367 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR367: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR367 Gene

Function for MIR367 Gene

Phenotypes From GWAS Catalog for MIR367 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR367 Gene

Localization for MIR367 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR367 Gene

Pathways & Interactions for MIR367 Gene

SuperPathways for MIR367 Gene

No Data Available

Interacting Proteins for MIR367 Gene

Gene Ontology (GO) - Biological Process for MIR367 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR367 Gene

Drugs & Compounds for MIR367 Gene

No Compound Related Data Available

Transcripts for MIR367 Gene

fRNAdb Secondary structures for MIR367 Gene

  • FR211479
  • hsa-mir-367_MI0000775_Homo_sapiens_miR-367_stem-loop_hairpin

mRNA/cDNA for MIR367 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR367 Gene

No ASD Table

Relevant External Links for MIR367 Gene

GeneLoc Exon Structure for
MIR367
ECgene alternative splicing isoforms for
MIR367

Expression for MIR367 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR367 Gene:

MIR367
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR367 Gene

Orthologs for MIR367 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR367 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-367 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-367 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-367 34
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-367 34
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir367 34
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-367 34
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-367 34
  • 90 (a)
OneToOne
Species where no ortholog for MIR367 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR367 Gene

ENSEMBL:
Gene Tree for MIR367 (if available)
TreeFam:
Gene Tree for MIR367 (if available)

Paralogs for MIR367 Gene

No data available for Paralogs for MIR367 Gene

Variants for MIR367 Gene

Sequence variations from dbSNP and Humsavar for MIR367 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1057519017 pathogenic, Alazami syndrome 112,647,715(-) AAAGGATA/AAAGGATAAAGGATA downstream_transcript_variant
rs1060499762 likely-pathogenic, Abnormality of brain morphology 112,647,384(-) A/T downstream_transcript_variant
rs750946801 likely-pathogenic, not provided 112,649,598(-) AAAAAAAA/AAAAAAA/AAAAAAAAA upstream_transcript_variant
rs62317770 likely-benign, not specified 112,647,388(-) G/A downstream_transcript_variant
rs1000855041 -- 112,647,944(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR367 Gene

Variant ID Type Subtype PubMed ID
nsv1006030 CNV gain 25217958
nsv1014926 CNV gain 25217958
nsv525715 CNV loss 19592680

Additional Variant Information for MIR367 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR367

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR367 Gene

Disorders for MIR367 Gene

Additional Disease Information for MIR367

No disorders were found for MIR367 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR367 Gene

Publications for MIR367 Gene

  1. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A … Zavolan M (BMC bioinformatics 2005) 1 3 58
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh MR … Kim KS (Developmental biology 2004) 1 3 58
  3. miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7. (PMID: 28000899) Xu J … Chen L (Oncology reports 2017) 3 58
  4. miR-367 promotes uveal melanoma cell proliferation and migration by regulating PTEN. (PMID: 28829890) Ling JW … Zhang ZC (Genetics and molecular research : GMR 2017) 3 58
  5. A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. (PMID: 26671749) Murray MJ … Coleman N (British journal of cancer 2016) 3 58

Products for MIR367 Gene

Sources for MIR367 Gene

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