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Aliases for MIR367 Gene

Subcategory (RNA class) for MIR367 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR367 Gene

  • MicroRNA 367 2 3 5
  • Hsa-Mir-367 3
  • MIRN367 3

External Ids for MIR367 Gene

Previous HGNC Symbols for MIR367 Gene

  • MIRN367

Previous GeneCards Identifiers for MIR367 Gene

  • GC04M113795
  • GC04M113569

Summaries for MIR367 Gene

Entrez Gene Summary for MIR367 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR367 Gene

MIR367 (MicroRNA 367) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR367 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR367

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR367 Gene

Genomics for MIR367 Gene

Regulatory Elements for MIR367 Gene

Enhancers for MIR367 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F112704 1.2 Ensembl ENCODE 11.2 -58.1 -58093 2.9 PKNOX1 ZNF76 KLF17 FEZF1 ZNF2 GLIS2 ZNF366 SCRT2 KLF7 ZNF391 MIR302B MIR302A MIR302C MIR302D MIR367 LARP7 RPL7AP30 ZGRF1 ENSG00000250046 WRBP1
GH04F112746 0.7 ENCODE 11.1 -102.3 -102317 7.2 BRD4 CTCF TEAD4 ZNF101 ETS1 ZNF316 GATA3 ZBTB48 POLR2A FOS ZGRF1 LOC105377371 LARP7 MIR302A MIR302C MIR302D MIR367 MIR302B GC04M112739 ENSG00000202536
GH04F112635 1.1 ENCODE 0.4 +10.7 10746 2.9 HDGF PKNOX1 CREB3L1 ARID4B SIN3A YBX1 DMAP1 ZNF2 YY1 ZNF143 ZGRF1 ENSG00000249509 LOC105377371 AP1AR LARP7 MIR367
GH04F112646 0.4 ENCODE 0.8 +2.7 2722 0.1 POLR2A KDM1A MIR367 ZGRF1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR367 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR367 Gene

Chromosome:
4
Start:
112,647,874 bp from pter
End:
112,647,941 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR367 Gene

Genes around MIR367 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR367 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR367 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR367 Gene

ORGUL Member Location for MIR367 Gene

ORGUL Member Location for MIR367 gene

Proteins for MIR367 Gene

Post-translational modifications for MIR367 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR367 Gene

Domains & Families for MIR367 Gene

Gene Families for MIR367 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR367: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR367 Gene

Function for MIR367 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR367 Gene

Localization for MIR367 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR367 Gene

Pathways & Interactions for MIR367 Gene

SuperPathways for MIR367 Gene

No Data Available

Interacting Proteins for MIR367 Gene

Gene Ontology (GO) - Biological Process for MIR367 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR367 Gene

Transcripts for MIR367 Gene

fRNAdb Secondary structures for MIR367 Gene

  • FR211479
  • hsa-mir-367_MI0000775_Homo_sapiens_miR-367_stem-loop_hairpin

mRNA/cDNA for MIR367 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR367 Gene

No ASD Table

Relevant External Links for MIR367 Gene

GeneLoc Exon Structure for
MIR367
ECgene alternative splicing isoforms for
MIR367

Expression for MIR367 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR367 Gene:

MIR367
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR367 Gene

Orthologs for MIR367 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR367 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-367 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-367 35
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-367 35
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-367 35
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir367 35
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-367 35
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-367 35
  • 90 (a)
OneToOne
Species where no ortholog for MIR367 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR367 Gene

ENSEMBL:
Gene Tree for MIR367 (if available)
TreeFam:
Gene Tree for MIR367 (if available)

Paralogs for MIR367 Gene

No data available for Paralogs for MIR367 Gene

Variants for MIR367 Gene

Sequence variations from dbSNP and Humsavar for MIR367 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs62317770 Likely benign 112,647,388(+) AAAAC(A/G)GGACA nc-transcript-variant, downstream-variant-500B, reference, missense
rs112220956 -- 112,649,884(+) TTTAA(A/C)ACAAT intron-variant, upstream-variant-2KB
rs113912016 -- 112,647,963(+) GCACA(-/CA)GTGTG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs114318553 -- 112,648,539(+) TTCCA(G/T)GTTAA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs115879346 -- 112,648,075(+) GGGGG(C/T)CCCTT intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR367 Gene

Variant ID Type Subtype PubMed ID
nsv1014926 CNV gain 25217958
nsv525715 CNV loss 19592680
nsv1006030 CNV gain 25217958

Relevant External Links for MIR367 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR367

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR367 Gene

Disorders for MIR367 Gene

Relevant External Links for MIR367

Human Genome Epidemiology (HuGE) Navigator
MIR367
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR367

No disorders were found for MIR367 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR367 Gene

Publications for MIR367 Gene

  1. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A. … Zavolan M. (BMC Bioinformatics 2005) 1 3 64
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 1 3 64
  3. miR-367 promotes proliferation and invasion of hepatocellular carcinoma cells by negatively regulating PTEN. (PMID: 26772880) Meng X. … Fan Q. (Biochem. Biophys. Res. Commun. 2016) 3 64
  4. A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. (PMID: 26671749) Murray M.J. … Coleman N. (Br. J. Cancer 2016) 3 64
  5. MicroRNA-367 is a potential diagnostic biomarker for patients with esophageal squamous cell carcinoma. (PMID: 26777997) Sun J. … Gao S. (Biochem. Biophys. Res. Commun. 2016) 3 64

Products for MIR367 Gene

Sources for MIR367 Gene

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