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Aliases for MIR367 Gene

Subcategory (RNA class) for MIR367 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR367 Gene

  • MicroRNA 367 2 3
  • Hsa-Mir-367 3
  • MIRN367 3

External Ids for MIR367 Gene

Previous HGNC Symbols for MIR367 Gene

  • MIRN367

Previous GeneCards Identifiers for MIR367 Gene

  • GC04M113795
  • GC04M113569

Summaries for MIR367 Gene

Entrez Gene Summary for MIR367 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR367 Gene

MIR367 (MicroRNA 367) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR367 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR367

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR367 Gene

Genomics for MIR367 Gene

Genomic Location for MIR367 Gene

Chromosome:
4
Start:
112,647,874 bp from pter
End:
112,647,941 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR367 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR367 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR367 Gene

ORGUL Member Location for MIR367 Gene

ORGUL Member Location for MIR367 gene

No data available for Regulatory Elements for MIR367 Gene

Proteins for MIR367 Gene

Post-translational modifications for MIR367 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR367 Gene

Domains & Families for MIR367 Gene

Gene Families for MIR367 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR367: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR367 Gene

Function for MIR367 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR367 Gene

Localization for MIR367 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR367 Gene

Pathways & Interactions for MIR367 Gene

SuperPathways for MIR367 Gene

No Data Available

Interacting Proteins for MIR367 Gene

Gene Ontology (GO) - Biological Process for MIR367 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR367 Gene

Drugs & Compounds for MIR367 Gene

No Compound Related Data Available

Transcripts for MIR367 Gene

fRNAdb Secondary structures for MIR367 Gene

  • FR211479
  • hsa-mir-367_MI0000775_Homo_sapiens_miR-367_stem-loop_hairpin

mRNA/cDNA for MIR367 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR367 Gene

No ASD Table

Relevant External Links for MIR367 Gene

GeneLoc Exon Structure for
MIR367
ECgene alternative splicing isoforms for
MIR367

Expression for MIR367 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR367 Gene

Orthologs for MIR367 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR367 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-367 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-367 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-367 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir367 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-367 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-367 36
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-367 36
  • 90 (a)
OneToOne
Species with no ortholog for MIR367:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR367 Gene

ENSEMBL:
Gene Tree for MIR367 (if available)
TreeFam:
Gene Tree for MIR367 (if available)

Paralogs for MIR367 Gene

No data available for Paralogs for MIR367 Gene

Variants for MIR367 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR367 Gene

Variant ID Type Subtype PubMed ID
nsv525715 CNV Loss 19592680

Relevant External Links for MIR367 Gene

HapMap Linkage Disequilibrium report
MIR367

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR367 Gene

Disorders for MIR367 Gene

Relevant External Links for MIR367

Human Genome Epidemiology (HuGE) Navigator
MIR367
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR367
genes like me logo Genes that share disorders with MIR367: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR367 Gene

Publications for MIR367 Gene

  1. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A. … Zavolan M. (BMC Bioinformatics 2005) 1 67
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 1 67
  3. miR-367 promotes epithelial-to-mesenchymal transition and invasion of pancreatic ductal adenocarcinoma cells by targeting the Smad7-TGF-I^ signalling pathway. (PMID: 25867271) Zhu Z. … Wang P. (Br. J. Cancer 2015) 67
  4. Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. (PMID: 24568633) Zhang Z. … Wu W.S. (Cell Reprogram 2014) 67
  5. Human cancer cell line microRNAs associated with in vitro sensitivity to paclitaxel. (PMID: 24220856) Chen N. … Lancaster J.M. (Oncol. Rep. 2014) 67

Products for MIR367 Gene

Sources for MIR367 Gene

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