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Aliases for MIR3666 Gene

Subcategory (RNA class) for MIR3666 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3666 Gene

  • MicroRNA 3666 2 3 5
  • Hsa-Mir-3666 3

External Ids for MIR3666 Gene

Previous GeneCards Identifiers for MIR3666 Gene

  • GC07U903068
  • GC07P114295

Summaries for MIR3666 Gene

Entrez Gene Summary for MIR3666 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3666 Gene

MIR3666 (MicroRNA 3666) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3666 Gene

Genomics for MIR3666 Gene

Regulatory Elements for MIR3666 Gene

Enhancers for MIR3666 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G114652 2 VISTA 0.7 +0.0 37 1.1 PKNOX1 ARNT FEZF1 ZNF2 ZNF121 GLIS2 KLF7 YY2 TSHZ1 ZNF488 FOXP2 MIR3666 GC07P114710
GH07G114647 1.6 VISTA 0.7 -4.1 -4128 2.6 ZNF664 HIC1 CTBP1 PRDM6 ZNF366 FEZF1 PRDM1 EP300 SP7 FOXP2 MIR3666 GC07P114622
GH07G114655 1.6 VISTA 0.7 +2.3 2342 1.3 EP300 FOXP2 MIR3666 GC07P114710
GH07G114659 2.3 VISTA FANTOM5 0.4 +7.5 7495 2.4 PKNOX1 ARNT ZSCAN4 FEZF1 SUPT20H ZNF843 RAD21 EP300 OSR2 PRDM6 FOXP2 MIR3666 GC07P114710
GH07G114686 2.3 VISTA ENCODE 0.3 +34.9 34943 2.9 PKNOX1 ZFP64 ZNF140 ZNF101 ZNF697 ZNF433 ZNF202 ZNF680 ZBTB11 ZNF426 GC07P114710 MIR3666
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3666 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3666 Gene

Chromosome:
7
Start:
114,653,345 bp from pter
End:
114,653,455 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR3666 Gene

Genes around MIR3666 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3666 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3666 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3666 Gene

Proteins for MIR3666 Gene

Post-translational modifications for MIR3666 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3666 Gene

Domains & Families for MIR3666 Gene

Gene Families for MIR3666 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3666: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3666 Gene

Function for MIR3666 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3666 Gene

Localization for MIR3666 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3666 Gene

Pathways & Interactions for MIR3666 Gene

SuperPathways for MIR3666 Gene

No Data Available

Interacting Proteins for MIR3666 Gene

Gene Ontology (GO) - Biological Process for MIR3666 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3666 Gene

Drugs & Compounds for MIR3666 Gene

No Compound Related Data Available

Transcripts for MIR3666 Gene

mRNA/cDNA for MIR3666 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3666 Gene

No ASD Table

Relevant External Links for MIR3666 Gene

GeneLoc Exon Structure for
MIR3666
ECgene alternative splicing isoforms for
MIR3666

Expression for MIR3666 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3666 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3666 Gene:

MIR3666
genes like me logo Genes that share expression patterns with MIR3666: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3666 Gene

Orthologs for MIR3666 Gene

Evolution for MIR3666 Gene

ENSEMBL:
Gene Tree for MIR3666 (if available)
TreeFam:
Gene Tree for MIR3666 (if available)

No data available for Orthologs for MIR3666 Gene

Paralogs for MIR3666 Gene

No data available for Paralogs for MIR3666 Gene

Variants for MIR3666 Gene

Sequence variations from dbSNP and Humsavar for MIR3666 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs879253771 Pathogenic 114,652,276(+) TGCAA(-/CA)GTTAG nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant
rs1000405334 -- 114,653,496(+) CAGTG(A/G)GAATG intron-variant, downstream-variant-500B
rs1005181777 -- 114,651,489(+) GATCT(C/G)TTTAA intron-variant, upstream-variant-2KB
rs1007858966 -- 114,651,564(+) ATGAT(G/T)TATTT intron-variant, upstream-variant-2KB
rs1011155376 -- 114,652,156(+) CACTA(A/G)GATCG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3666 Gene

Variant ID Type Subtype PubMed ID
nsv7405 OTHER inversion 18451855

Relevant External Links for MIR3666 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3666

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3666 Gene

Disorders for MIR3666 Gene

Relevant External Links for MIR3666

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3666

No disorders were found for MIR3666 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3666 Gene

Publications for MIR3666 Gene

  1. MicroRNA-3666 Regulates Thyroid Carcinoma Cell Proliferation via MET. (PMID: 26937629) Wang G. … Chen L. (Cell. Physiol. Biochem. 2016) 3 64
  2. MicroRNA-3666-induced suppression of SIRT7 inhibits the growth of non-small cell lung cancer cells. (PMID: 27599551) Shi H. … Fang P. (Oncol. Rep. 2016) 3 64
  3. Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment. (PMID: 20559549) Smith B. … Sikorska M. (PLoS ONE 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. (PMID: 15735639) Xie X. … Kellis M. (Nature 2005) 3 64

Products for MIR3666 Gene

Sources for MIR3666 Gene

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