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Aliases for MIR3666 Gene

Subcategory (RNA class) for MIR3666 Gene


Quality Score for this RNA gene is


Aliases for MIR3666 Gene

  • MicroRNA 3666 2 3 5
  • Hsa-Mir-3666 3

External Ids for MIR3666 Gene

Previous GeneCards Identifiers for MIR3666 Gene

  • GC07U903068
  • GC07P114295

Summaries for MIR3666 Gene

Entrez Gene Summary for MIR3666 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3666 Gene

MIR3666 (MicroRNA 3666) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3666 Gene

Genomics for MIR3666 Gene

Regulatory Elements for MIR3666 Gene

Enhancers for MIR3666 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F114652 2.2 VISTA Ensembl 0.8 +0.2 178 1.4 PKNOX1 FEZF1 ZNF2 ZNF121 GLIS2 KLF7 YY2 TSHZ1 ZNF488 ZNF518A RAC1P6 LINC01392 FOXP2 MIR3666 GC07P114710
GH07F114647 1.6 VISTA 0.8 -4.1 -4128 2.6 HIC1 ZNF664 CTBP1 ZNF366 FEZF1 PRDM1 SP7 FOXP2 MIR3666 GC07P114622
GH07F114655 1.5 VISTA 0.8 +2.3 2342 1.3 FOXP2 MIR3666 GC07P114710
GH07F114659 2.2 VISTA FANTOM5 0.4 +7.5 7495 2.4 OSR2 PKNOX1 ZNF366 SCRT2 FEZF1 SUPT20H ZNF843 WT1 SP7 FOXP2 MIR3666 GC07P114710
GH07F114686 2.3 VISTA ENCODE 0.3 +34.9 34943 2.9 PKNOX1 ZFP64 ZNF140 ZNF101 ZNF433 ZNF202 ZNF680 ZBTB11 REST ZBTB8A LINC01393 GC07P114710 MIR3666
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3666 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3666 Gene

114,653,345 bp from pter
114,653,455 bp from pter
111 bases
Plus strand

Genomic View for MIR3666 Gene

Genes around MIR3666 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3666 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3666 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3666 Gene

Proteins for MIR3666 Gene

Post-translational modifications for MIR3666 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3666 Gene

Domains & Families for MIR3666 Gene

Gene Families for MIR3666 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3666: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3666 Gene

Function for MIR3666 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3666 Gene

Localization for MIR3666 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3666 Gene

Pathways & Interactions for MIR3666 Gene

SuperPathways for MIR3666 Gene

No Data Available

Interacting Proteins for MIR3666 Gene

Gene Ontology (GO) - Biological Process for MIR3666 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3666 Gene

Transcripts for MIR3666 Gene

mRNA/cDNA for MIR3666 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3666 Gene

No ASD Table

Relevant External Links for MIR3666 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3666 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3666 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3666 Gene:

genes like me logo Genes that share expression patterns with MIR3666: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3666 Gene

Orthologs for MIR3666 Gene

Evolution for MIR3666 Gene

Gene Tree for MIR3666 (if available)
Gene Tree for MIR3666 (if available)

No data available for Orthologs for MIR3666 Gene

Paralogs for MIR3666 Gene

No data available for Paralogs for MIR3666 Gene

Variants for MIR3666 Gene

Sequence variations from dbSNP and Humsavar for MIR3666 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs879253771 Pathogenic 114,652,276(+) TGCAA(-/CA)GTTAG nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant
rs10234184 -- 114,652,881(+) AAAAA(A/G)AATTC intron-variant, upstream-variant-2KB
rs10953765 -- 114,651,380(+) ATTAT(A/G)TATTA intron-variant, upstream-variant-2KB
rs112530159 -- 114,652,489(+) TGTAC(C/T)TATCA intron-variant, upstream-variant-2KB
rs115129935 -- 114,653,899(+) AAAAC(A/G/T)CTTCT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3666 Gene

Variant ID Type Subtype PubMed ID
nsv7405 OTHER inversion 18451855

Relevant External Links for MIR3666 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3666 Gene

Disorders for MIR3666 Gene

Relevant External Links for MIR3666

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR3666 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3666 Gene

Publications for MIR3666 Gene

  1. MicroRNA-3666 Regulates Thyroid Carcinoma Cell Proliferation via MET. (PMID: 26937629) Wang G. … Chen L. (Cell. Physiol. Biochem. 2016) 3 64
  2. Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment. (PMID: 20559549) Smith B. … Sikorska M. (PLoS ONE 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. (PMID: 15735639) Xie X. … Kellis M. (Nature 2005) 3 64

Products for MIR3666 Gene

Sources for MIR3666 Gene

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