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Aliases for MIR3661 Gene

Subcategory (RNA class) for MIR3661 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3661 Gene

  • MicroRNA 3661 2 3 5
  • Hsa-Mir-3661 3
  • Mir-3661 3

External Ids for MIR3661 Gene

Previous GeneCards Identifiers for MIR3661 Gene

  • GC05U901488
  • GC05P133565

Summaries for MIR3661 Gene

Entrez Gene Summary for MIR3661 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3661 Gene

MIR3661 (MicroRNA 3661) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3661 Gene

Genomics for MIR3661 Gene

Regulatory Elements for MIR3661 Gene

Enhancers for MIR3661 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F134223 0.2 ENCODE 0.8 +0.3 302 5.0 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 FOS KLF13 SKP1 PPP2CA ENSG00000272772 MIR3661
GH05F134219 0.5 Ensembl 0.4 -6.2 -6157 0.4 MTA2 IKZF1 NBN TBX21 DDX46 VDAC1 MIR3661 GC05M134183
GH05F134211 0.6 Ensembl 0.4 -14.7 -14656 0.2 ZNF121 MIR3661 GC05M134183
GH05F134209 1.1 Ensembl 0.3 -15.7 -15657 1.4 OSR2 HLF PRDM10 PPP2CA GC05M134183 MIR3661
GH05F134207 0.6 Ensembl 0.3 -18.2 -18157 0.4 GC05M134183 MIR3661
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3661 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3661 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001290506 -157 3601 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 FOS KLF13

Genomic Location for MIR3661 Gene

Chromosome:
5
Start:
134,225,757 bp from pter
End:
134,225,852 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR3661 Gene

Genes around MIR3661 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3661 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3661 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3661 Gene

Proteins for MIR3661 Gene

Post-translational modifications for MIR3661 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3661 Gene

Domains & Families for MIR3661 Gene

Gene Families for MIR3661 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3661: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3661 Gene

Function for MIR3661 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3661 Gene

Localization for MIR3661 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3661 Gene

Pathways & Interactions for MIR3661 Gene

SuperPathways for MIR3661 Gene

No Data Available

Interacting Proteins for MIR3661 Gene

Gene Ontology (GO) - Biological Process for MIR3661 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3661 Gene

Transcripts for MIR3661 Gene

mRNA/cDNA for MIR3661 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3661 Gene

No ASD Table

Relevant External Links for MIR3661 Gene

GeneLoc Exon Structure for
MIR3661
ECgene alternative splicing isoforms for
MIR3661

Expression for MIR3661 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3661 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3661 Gene:

MIR3661
genes like me logo Genes that share expression patterns with MIR3661: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3661 Gene

Orthologs for MIR3661 Gene

Evolution for MIR3661 Gene

ENSEMBL:
Gene Tree for MIR3661 (if available)
TreeFam:
Gene Tree for MIR3661 (if available)

No data available for Orthologs for MIR3661 Gene

Paralogs for MIR3661 Gene

No data available for Paralogs for MIR3661 Gene

Variants for MIR3661 Gene

Sequence variations from dbSNP and Humsavar for MIR3661 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10044929 -- 134,224,237(+) TTAAA(C/T)CTTTA intron-variant, upstream-variant-2KB
rs10050924 -- 134,225,565(+) GCGGC(A/G)GCAAC intron-variant, upstream-variant-2KB
rs1063629 -- 134,225,918(-) CCGTG(C/T)GCGGG downstream-variant-500B, utr-variant-5-prime
rs112421900 -- 134,225,515(+) CCGGC(C/G/T)GACTC intron-variant, upstream-variant-2KB
rs113154913 -- 134,225,612(+) TAGGA(A/G)GCCGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3661 Gene

Variant ID Type Subtype PubMed ID
nsv599732 CNV loss 21841781

Relevant External Links for MIR3661 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3661

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3661 Gene

Disorders for MIR3661 Gene

Relevant External Links for MIR3661

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3661

No disorders were found for MIR3661 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3661 Gene

Publications for MIR3661 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. (PMID: 20532037) Hansen T.B. … Kjems J. (PLoS ONE 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3661 Gene

Sources for MIR3661 Gene

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