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Aliases for MIR365B Gene

Subcategory (RNA class) for MIR365B Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR365B Gene

  • MicroRNA 365b 2 3
  • MicroRNA 365-2 2 3
  • Hsa-Mir-365-2 3
  • Hsa-Mir-365b 3
  • MIRN365-2 3
  • MIR365-2 3

External Ids for MIR365B Gene

ORGUL Members for MIR365B Gene

Previous HGNC Symbols for MIR365B Gene

  • MIRN365-2
  • MIR365-2

Previous GeneCards Identifiers for MIR365B Gene

  • GC17P029903
  • GC17P029904
  • GC17P029910
  • GC17P029915
  • GC17P029919

Summaries for MIR365B Gene

Entrez Gene Summary for MIR365B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR365B Gene

MIR365B (MicroRNA 365b) is an RNA Gene, and is affiliated with the undefined RNA class. Diseases associated with MIR365B include multiple myeloma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR365B Gene

Genomics for MIR365B Gene

Genomic Location for MIR365B Gene

Start:
31,575,411 bp from pter
End:
31,575,521 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR365B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR365B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR365B Gene

No data available for Regulatory Elements for MIR365B Gene

Proteins for MIR365B Gene

Post-translational modifications for MIR365B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR365B Gene

Domains for MIR365B Gene

Gene Families for MIR365B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR365B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR365B Gene

Function for MIR365B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR365B Gene

Localization for MIR365B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR365B Gene

Pathways for MIR365B Gene

SuperPathways for MIR365B Gene

No Data Available

Interacting Proteins for MIR365B Gene

Gene Ontology (GO) - Biological Process for MIR365B Gene

None

No data available for Pathways by source for MIR365B Gene

Transcripts for MIR365B Gene

mRNA/cDNA for MIR365B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR365B Gene

No ASD Table

Relevant External Links for MIR365B Gene

GeneLoc Exon Structure for
MIR365B
ECgene alternative splicing isoforms for
MIR365B

Expression for MIR365B Gene

mRNA expression in normal human tissues for MIR365B Gene

genes like me logo Genes that share expressions with MIR365B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR365B Gene

Orthologs for MIR365B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR365B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-365-2 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-365-2 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir365-2 36
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-365-2 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-365-2 36
  • 96 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-365-2 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-365 36
  • 94 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-365-2 36
  • 88 (a)
OneToMany
dre-mir-365-3 36
  • 89 (a)
OneToMany
Species with no ortholog for MIR365B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR365B Gene

ENSEMBL:
Gene Tree for MIR365B (if available)
TreeFam:
Gene Tree for MIR365B (if available)

Paralogs for MIR365B Gene

No data available for Paralogs for MIR365B Gene

Variants for MIR365B Gene

Sequence variations from dbSNP and Humsavar for MIR365B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs75737719 -- 31,575,909(+) GTTGA(A/G)GCAGG downstream-variant-500B
rs77298620 -- 31,575,937(+) TCTGC(A/G)CAGGA downstream-variant-500B
rs138952419 -- 31,575,880(+) ACAAG(A/T)TGCCC downstream-variant-500B
rs142113910 -- 31,575,919(+) GAGTA(A/G)AGGAG downstream-variant-500B
rs536514237 -- 31,575,863(+) CAACA(C/G)AGTTG downstream-variant-500B

Relevant External Links for MIR365B Gene

HapMap Linkage Disequilibrium report
MIR365B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR365B Gene

Disorders for MIR365B Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR365B Gene in MalaCards »

(1) Diseases for MIR365B Gene including...

genes like me logo Genes that share disorders with MIR365B: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR365B Gene

Publications for MIR365B Gene

  1. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. (PMID: 15735639) Xie X. … Kellis M. (Nature 2005) 3
  2. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR365B Gene

Sources for MIR365B Gene

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