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Aliases for MIR365B Gene

Subcategory (RNA class) for MIR365B Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR365B Gene

  • MicroRNA 365b 2 3 5
  • MicroRNA 365-2 2 3
  • Hsa-Mir-365-2 3
  • Hsa-Mir-365b 3
  • MIRN365-2 3
  • Mir-365b 3
  • MIR365-2 3

External Ids for MIR365B Gene

ORGUL Members for MIR365B Gene

Previous HGNC Symbols for MIR365B Gene

  • MIRN365-2
  • MIR365-2

Previous GeneCards Identifiers for MIR365B Gene

  • GC17P029903
  • GC17P029904
  • GC17P029910
  • GC17P029915
  • GC17P029919

Summaries for MIR365B Gene

Entrez Gene Summary for MIR365B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR365B Gene

MIR365B (MicroRNA 365b) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR365B Gene

Genomics for MIR365B Gene

Genomic Location for MIR365B Gene

Chromosome:
17
Start:
31,575,411 bp from pter
End:
31,575,521 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR365B Gene

Genes around MIR365B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR365B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR365B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR365B Gene

No data available for Regulatory Elements for MIR365B Gene

Proteins for MIR365B Gene

Post-translational modifications for MIR365B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR365B Gene

Domains & Families for MIR365B Gene

Gene Families for MIR365B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR365B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR365B Gene

Function for MIR365B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR365B Gene

Localization for MIR365B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR365B Gene

Pathways & Interactions for MIR365B Gene

SuperPathways for MIR365B Gene

No Data Available

Interacting Proteins for MIR365B Gene

Gene Ontology (GO) - Biological Process for MIR365B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR365B Gene

Drugs & Compounds for MIR365B Gene

No Compound Related Data Available

Transcripts for MIR365B Gene

mRNA/cDNA for MIR365B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR365B Gene

No ASD Table

Relevant External Links for MIR365B Gene

GeneLoc Exon Structure for
MIR365B
ECgene alternative splicing isoforms for
MIR365B

Expression for MIR365B Gene

mRNA expression in normal human tissues for MIR365B Gene

genes like me logo Genes that share expression patterns with MIR365B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR365B Gene

Orthologs for MIR365B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR365B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-365-2 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-365-2 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-365-2 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir365-2 36
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-365-2 36
  • 94 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-365-2 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-365 36
  • 94 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-365-2 36
  • 88 (a)
OneToMany
dre-mir-365-3 36
  • 89 (a)
OneToMany
Species with no ortholog for MIR365B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR365B Gene

ENSEMBL:
Gene Tree for MIR365B (if available)
TreeFam:
Gene Tree for MIR365B (if available)

Paralogs for MIR365B Gene

No data available for Paralogs for MIR365B Gene

Variants for MIR365B Gene

Sequence variations from dbSNP and Humsavar for MIR365B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs77298620 -- 31,575,937(+) TCTGC(A/G)CAGGA downstream-variant-500B
rs75737719 -- 31,575,909(+) GTTGA(A/G)GCAGG downstream-variant-500B
rs760285221 -- 31,575,870(+) GTTGG(G/T)CTGGA downstream-variant-500B
rs576809572 -- 31,575,985(+) AACAT(A/G)GCAGA downstream-variant-500B
rs536514237 -- 31,575,863(+) CAACA(C/G)AGTTG downstream-variant-500B

Relevant External Links for MIR365B Gene

HapMap Linkage Disequilibrium report
MIR365B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR365B Gene

Disorders for MIR365B Gene

Relevant External Links for MIR365B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR365B

No disorders were found for MIR365B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR365B Gene

Publications for MIR365B Gene

  1. MiR-365b-3p, down-regulated in retinoblastoma, regulates cell cycle progression and apoptosis of human retinoblastoma cells by targeting PAX6. (PMID: 23660406) Wang J. … Hu Q. (FEBS Lett. 2013) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  3. Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas. (PMID: 19144710) Zhu J.Y. … Meister G. (J. Virol. 2009) 3
  4. Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma. (PMID: 19883314) Unno K. … Wickrema A. (Leuk. Lymphoma 2009) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR365B Gene

Sources for MIR365B Gene

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