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Aliases for MIR365A Gene

Subcategory (RNA class) for MIR365A Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR365A Gene

  • MicroRNA 365a 2 3 5
  • MicroRNA 365-1 2 3
  • Hsa-Mir-365-1 3
  • Hsa-Mir-365a 3
  • MIRN365-1 3
  • Mir-365a 3
  • MIR365-1 3

External Ids for MIR365A Gene

ORGUL Members for MIR365A Gene

Previous HGNC Symbols for MIR365A Gene

  • MIRN365-1
  • MIR365-1

Previous GeneCards Identifiers for MIR365A Gene

  • GC16P014404
  • GC16P014405

Summaries for MIR365A Gene

Entrez Gene Summary for MIR365A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR365A Gene

MIR365A (MicroRNA 365a) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR365A Gene

Genomics for MIR365A Gene

Regulatory Elements for MIR365A Gene

Promoters for MIR365A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR365A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR365A Gene

Chromosome:
16
Start:
14,309,270 bp from pter
End:
14,309,380 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR365A Gene

Genes around MIR365A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR365A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR365A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR365A Gene

Proteins for MIR365A Gene

Post-translational modifications for MIR365A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR365A Gene

Domains & Families for MIR365A Gene

Gene Families for MIR365A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR365A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR365A Gene

Function for MIR365A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR365A Gene

Localization for MIR365A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR365A Gene

Pathways & Interactions for MIR365A Gene

SuperPathways for MIR365A Gene

No Data Available

Interacting Proteins for MIR365A Gene

Gene Ontology (GO) - Biological Process for MIR365A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR365A Gene

Drugs & Compounds for MIR365A Gene

No Compound Related Data Available

Transcripts for MIR365A Gene

mRNA/cDNA for MIR365A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR365A Gene

No ASD Table

Relevant External Links for MIR365A Gene

GeneLoc Exon Structure for
MIR365A
ECgene alternative splicing isoforms for
MIR365A

Expression for MIR365A Gene

mRNA expression in normal human tissues for MIR365A Gene

genes like me logo Genes that share expression patterns with MIR365A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR365A Gene

Orthologs for MIR365A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR365A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-365-1 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-365-1 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-365 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir365-1 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-365-1 36
  • 99 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-365-1 36
  • 100 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-365-1 36
  • 88 (a)
OneToOne
Species with no ortholog for MIR365A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR365A Gene

ENSEMBL:
Gene Tree for MIR365A (if available)
TreeFam:
Gene Tree for MIR365A (if available)

Paralogs for MIR365A Gene

No data available for Paralogs for MIR365A Gene

Variants for MIR365A Gene

Sequence variations from dbSNP and Humsavar for MIR365A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs30230 -- 14,308,480(+) GCACC(C/T)GGGAC upstream-variant-2KB
rs30231 -- 14,308,408(+) AAGGT(C/T)ATATG upstream-variant-2KB
rs30232 -- 14,308,105(+) TACAG(A/G)TGCCC upstream-variant-2KB
rs721698 -- 14,308,175(-) ACCGA(C/T)GCCCC upstream-variant-2KB
rs5815822 -- 14,308,931(+) AAGGA(-/TTTGTTGT)ATAAC upstream-variant-2KB

Relevant External Links for MIR365A Gene

HapMap Linkage Disequilibrium report
MIR365A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR365A Gene

Disorders for MIR365A Gene

Relevant External Links for MIR365A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR365A

No disorders were found for MIR365A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR365A Gene

Publications for MIR365A Gene

  1. Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells. (PMID: 24153013) Akbari Moqadam F. … den Boer M.L. (Leukemia 2014) 3
  2. MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX. (PMID: 24216611) Hamada S. … Shimosegawa T. (Cell. Signal. 2014) 3
  3. miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. (PMID: 24374827) Gastaldi C. … Rezzonico R. (Carcinogenesis 2014) 3
  4. miR-365 promotes cutaneous squamous cell carcinoma (CSCC) through targeting nuclear factor I/B (NFIB). (PMID: 24949940) Zhou M. … Ding Z. (PLoS ONE 2014) 3
  5. MicroRNA-365 regulates NKX2-1, a key mediator of lung cancer. (PMID: 23507558) Kang S.M. … Cho J.Y. (Cancer Lett. 2013) 3

Products for MIR365A Gene

Sources for MIR365A Gene

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