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Aliases for MIR3659 Gene

Subcategory (RNA class) for MIR3659 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3659 Gene

  • MicroRNA 3659 2 3 5
  • Hsa-Mir-3659 3
  • Mir-3659 3

External Ids for MIR3659 Gene

Previous GeneCards Identifiers for MIR3659 Gene

  • GC01U903124
  • GC01P038556

Summaries for MIR3659 Gene

Entrez Gene Summary for MIR3659 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3659 Gene

MIR3659 (MicroRNA 3659) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3659 Gene

Genomics for MIR3659 Gene

Regulatory Elements for MIR3659 Gene

Enhancers for MIR3659 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F038094 1.9 VISTA 0.4 +6.0 5998 1.4 BCOR SMARCA5 PKNOX1 ZMYM3 FEZF1 ZBTB8A ZBTB40 HDAC2 ZNF341 ADNP MIR3659 GC01P038138
GH01F038125 0.8 FANTOM5 ENCODE 0.3 +37.1 37144 1.3 KLF1 ZFHX2 GATA3 EGR2 POU3F1 C1orf122 GC01P038138 MIR3659
GH01F038122 0.7 ENCODE 0.3 +34.5 34535 1.8 KLF1 KLF17 DPF2 ZIC2 E2F1 GATA3 ZFHX2 ZBTB48 GLIS1 FOSL2 GC01P038138 MIR3659
GH01F038117 0.6 ENCODE 0.3 +28.4 28390 0.3 BCOR ZNF146 ZNF580 ZBTB33 RAD21 MAFK YY1 GC01P038138 MIR3659
GH01F038114 0.5 Ensembl 0.3 +25.4 25370 0.8 ZNF316 ZNF623 EMSY GC01P038138 MIR3659
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3659 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3659 Gene

Chromosome:
1
Start:
38,089,231 bp from pter
End:
38,089,329 bp from pter
Size:
99 bases
Orientation:
Plus strand

Genomic View for MIR3659 Gene

Genes around MIR3659 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3659 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3659 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3659 Gene

Proteins for MIR3659 Gene

Post-translational modifications for MIR3659 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3659 Gene

Domains & Families for MIR3659 Gene

Gene Families for MIR3659 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3659: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3659 Gene

Function for MIR3659 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3659 Gene

Localization for MIR3659 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3659 Gene

Pathways & Interactions for MIR3659 Gene

SuperPathways for MIR3659 Gene

No Data Available

Interacting Proteins for MIR3659 Gene

Gene Ontology (GO) - Biological Process for MIR3659 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3659 Gene

Transcripts for MIR3659 Gene

mRNA/cDNA for MIR3659 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3659 Gene

No ASD Table

Relevant External Links for MIR3659 Gene

GeneLoc Exon Structure for
MIR3659
ECgene alternative splicing isoforms for
MIR3659

Expression for MIR3659 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3659 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3659 Gene:

MIR3659
genes like me logo Genes that share expression patterns with MIR3659: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3659 Gene

Orthologs for MIR3659 Gene

Evolution for MIR3659 Gene

ENSEMBL:
Gene Tree for MIR3659 (if available)
TreeFam:
Gene Tree for MIR3659 (if available)

No data available for Orthologs for MIR3659 Gene

Paralogs for MIR3659 Gene

No data available for Paralogs for MIR3659 Gene

Variants for MIR3659 Gene

Sequence variations from dbSNP and Humsavar for MIR3659 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111227048 -- 38,089,205(+) TGTGT(-/G)TGGAT intron-variant, upstream-variant-2KB
rs11294805 -- 38,089,207(+) TGTGT(-/G)GATGC intron-variant, upstream-variant-2KB
rs12077698 -- 38,088,049(+) GCTGC(C/G)ATATG intron-variant, upstream-variant-2KB
rs12083494 -- 38,089,673(+) tctgc(C/T)ggtct intron-variant, downstream-variant-500B
rs138474129 -- 38,089,637(+) CTGTG(C/T)ATGTA intron-variant, downstream-variant-500B

Relevant External Links for MIR3659 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3659

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3659 Gene

Disorders for MIR3659 Gene

Relevant External Links for MIR3659

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3659

No disorders were found for MIR3659 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3659 Gene

Publications for MIR3659 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. (PMID: 20532037) Hansen T.B. … Kjems J. (PLoS ONE 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3659 Gene

Sources for MIR3659 Gene

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