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Aliases for MIR3657 Gene

Subcategory (RNA class) for MIR3657 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3657 Gene

  • MicroRNA 3657 2 3 5
  • Hsa-Mir-3657 3

External Ids for MIR3657 Gene

Previous GeneCards Identifiers for MIR3657 Gene

  • GC12U901522
  • GC12M112477

Summaries for MIR3657 Gene

Entrez Gene Summary for MIR3657 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3657 Gene

MIR3657 (MicroRNA 3657) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3657 Gene

Genomics for MIR3657 Gene

Regulatory Elements for MIR3657 Gene

Enhancers for MIR3657 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G112025 0.8 dbSUPER 0.4 +11.5 11486 2.0 ZNF48 ZNF664 ZNF121 ZNF316 POLR2A PRDM10 MAFK IKZF2 STAT1 MTA2 TMEM116 ALDH2 ADAM1A ENSG00000274227 MIR3657
GH12G112021 0.6 dbSUPER 0.4 +15.0 15003 2.0 ZNF263 PAF1 ZNF121 ZNF362 POLR2A ZSCAN4 TMEM116 ADAM1A ENSG00000274227 MIR3657
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3657 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3657 Gene

Chromosome:
12
Start:
112,037,599 bp from pter
End:
112,037,715 bp from pter
Size:
117 bases
Orientation:
Minus strand

Genomic View for MIR3657 Gene

Genes around MIR3657 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3657 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3657 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3657 Gene

Proteins for MIR3657 Gene

Post-translational modifications for MIR3657 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3657 Gene

Domains & Families for MIR3657 Gene

Gene Families for MIR3657 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3657: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3657 Gene

Function for MIR3657 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3657 Gene

Localization for MIR3657 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3657 Gene

Pathways & Interactions for MIR3657 Gene

SuperPathways for MIR3657 Gene

No Data Available

Interacting Proteins for MIR3657 Gene

Gene Ontology (GO) - Biological Process for MIR3657 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3657 Gene

Drugs & Compounds for MIR3657 Gene

No Compound Related Data Available

Transcripts for MIR3657 Gene

mRNA/cDNA for MIR3657 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3657 Gene

No ASD Table

Relevant External Links for MIR3657 Gene

GeneLoc Exon Structure for
MIR3657
ECgene alternative splicing isoforms for
MIR3657

Expression for MIR3657 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3657 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3657 Gene:

MIR3657
genes like me logo Genes that share expression patterns with MIR3657: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3657 Gene

Orthologs for MIR3657 Gene

Evolution for MIR3657 Gene

ENSEMBL:
Gene Tree for MIR3657 (if available)
TreeFam:
Gene Tree for MIR3657 (if available)

No data available for Orthologs for MIR3657 Gene

Paralogs for MIR3657 Gene

No data available for Paralogs for MIR3657 Gene

Variants for MIR3657 Gene

Sequence variations from dbSNP and Humsavar for MIR3657 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1003096985 -- 112,037,723(+) AACAT(A/T)AGTGA intron-variant, upstream-variant-2KB
rs1008966518 -- 112,039,003(+) CAAAA(A/C)AAACA intron-variant, upstream-variant-2KB
rs1009181803 -- 112,038,642(+) CTTCC(A/C)TGGGC intron-variant, upstream-variant-2KB
rs1009222599 -- 112,038,206(+) ATGGG(A/G)TTTCA intron-variant, upstream-variant-2KB
rs1010726492 -- 112,039,511(+) AGGCC(G/T)TCATC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3657 Gene

Variant ID Type Subtype PubMed ID
nsv52789 CNV deletion 16902084

Relevant External Links for MIR3657 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3657

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3657 Gene

Disorders for MIR3657 Gene

Relevant External Links for MIR3657

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3657

No disorders were found for MIR3657 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3657 Gene

Publications for MIR3657 Gene

  1. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E. … Sitbon E. (Nucleic Acids Res. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3657 Gene

Sources for MIR3657 Gene

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