Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3655 Gene

Subcategory (RNA class) for MIR3655 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3655 Gene

  • MicroRNA 3655 2 3
  • IK Cytokine, Down-Regulator Of HLA II 5
  • Hsa-Mir-3655 3
  • Cytokine IK 4
  • Protein RER 4
  • IK Factor 4
  • RED 4
  • RER 4
  • IK 5

External Ids for MIR3655 Gene

Previous GeneCards Identifiers for MIR3655 Gene

  • GC05U901508
  • GC05P140036
  • GC05P140045
  • GC05P140069
  • GC05P141417
  • GC05P141561
  • GC05P141663
  • GC05P141764

Summaries for MIR3655 Gene

Entrez Gene Summary for MIR3655 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3655 Gene

MIR3655 (MicroRNA 3655) is an RNA Gene, and is affiliated with the miRNA class.

UniProtKB/Swiss-Prot for MIR3655 Gene

  • May bind to chromatin.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3655 Gene

Genomics for MIR3655 Gene

Regulatory Elements for MIR3655 Gene

Enhancers for MIR3655 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F140622 0.5 Ensembl 11 -23.8 -23834 0.5 HDAC1 RNF2 MTA2 TAL1 CEBPB DPF2 ARID1B ATF3 NCOR1 SMARCA4 TMCO6 EIF4EBP3 IK MIR3655 NDUFA2 MIR6831 SLC35A4 APBB3 CD14 RPL36P11
GH05F140710 0.2 ENCODE 10.8 +63.9 63926 1.9 PKNOX1 ARNT WRNIP1 ARID4B SIN3A FEZF1 ZNF2 YY1 CBX5 ZNF143 PCDHA4 HDAC3 LOC102723915 HARS SRA1 TMCO6 PCDHA1 LOC101929719 WDR55 PCDHA2
GH05F140588 1.2 FANTOM5 Ensembl ENCODE 10.7 -56.7 -56658 4.4 HDGF CREB3L1 ZFP64 ARID4B SIN3A ZNF2 ZNF48 ZNF143 DEK ZNF263 TMCO6 APBB3 CD14 EIF4EBP3 PCDHB19P LINC01024 PCDHB17P SLC35A4 PCDHA2 LOC101929719
GH05F140573 0.5 Ensembl ENCODE 10.6 -72.7 -72694 1.3 ZNF316 ATF3 IKZF1 ZBTB33 RAD21 NR2F2 TEAD3 YY1 EIF4EBP3 WDR55 DND1 IK MIR3655 NDUFA2 HARS2 GC05P141897 APBB3 MIR6831
GH05F140575 1.3 Ensembl ENCODE 10.6 -71.6 -71595 0.4 ELF3 HDGF CTCF SAP130 ARID4B CEBPG ZNF48 RAD21 GATAD1 SMC3 EIF4EBP3 WDR55 DND1 IK MIR3655 NDUFA2 GC05P141897 MIR6831 APBB3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3655 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3655 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001291878 543 2400 HDGF PKNOX1 ARNT SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF548 FOS

Genomic Location for MIR3655 Gene

Chromosome:
5
Start:
140,647,058 bp from pter
End:
140,662,479 bp from pter
Size:
15,422 bases
Orientation:
Plus strand

Genomic View for MIR3655 Gene

Genes around MIR3655 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3655 Gene

Proteins for MIR3655 Gene

  • Protein details for MIR3655 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13123-RED_HUMAN
    Recommended name:
    Protein Red
    Protein Accession:
    Q13123
    Secondary Accessions:
    • Q6IPD8

    Protein attributes for MIR3655 Gene

    Size:
    557 amino acids
    Molecular mass:
    65602 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MIR3655 Gene

Post-translational modifications for MIR3655 Gene

  • Ubiquitination at Lys 164, Lys 173, and Lys 260
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for MIR3655 Gene

Domains & Families for MIR3655 Gene

Gene Families for MIR3655 Gene

Protein Domains for MIR3655 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q13123

UniProtKB/Swiss-Prot:

RED_HUMAN :
  • Belongs to the RED family.
Family:
  • Belongs to the RED family.
genes like me logo Genes that share domains with MIR3655: view

No data available for Suggested Antigen Peptide Sequences for MIR3655 Gene

Function for MIR3655 Gene

Molecular function for MIR3655 Gene

UniProtKB/Swiss-Prot Function:
May bind to chromatin.

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3655 Gene

Localization for MIR3655 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MIR3655 Gene

Gene Ontology (GO) - Cellular Components for MIR3655 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with MIR3655: view

No data available for Subcellular locations from COMPARTMENTS for MIR3655 Gene

Pathways & Interactions for MIR3655 Gene

SuperPathways for MIR3655 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3655 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response TAS --
GO:0007267 cell-cell signaling TAS --
genes like me logo Genes that share ontologies with MIR3655: view

No data available for Pathways by source and SIGNOR curated interactions for MIR3655 Gene

Transcripts for MIR3655 Gene

mRNA/cDNA for MIR3655 Gene

(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3655 Gene

No ASD Table

Relevant External Links for MIR3655 Gene

GeneLoc Exon Structure for
MIR3655
ECgene alternative splicing isoforms for
MIR3655

Expression for MIR3655 Gene

mRNA expression in normal human tissues for MIR3655 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3655 Gene:

MIR3655

mRNA Expression by UniProt/SwissProt for MIR3655 Gene:

Q13123-RED_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expression patterns with MIR3655: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for MIR3655 Gene

Orthologs for MIR3655 Gene

This gene was present in the common ancestor of animals.

Orthologs for MIR3655 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia IK 35
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ik 35
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IK 35
  • 92 (a)
OneToOne
chicken
(Gallus gallus)
Aves IK 35
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IK 35
  • 51 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ik 35
  • 85 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG18005 35
  • 46 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea smu-2 35
  • 35 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10369 35
  • 52 (a)
OneToOne
Species where no ortholog for MIR3655 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MIR3655 Gene

ENSEMBL:
Gene Tree for MIR3655 (if available)
TreeFam:
Gene Tree for MIR3655 (if available)

Paralogs for MIR3655 Gene

Pseudogenes.org Pseudogenes for MIR3655 Gene

genes like me logo Genes that share paralogs with MIR3655: view

No data available for Paralogs for MIR3655 Gene

Variants for MIR3655 Gene

Sequence variations from dbSNP and Humsavar for MIR3655 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs757982865 Pathogenic 140,647,330(+) CCTTC(G/T)TCAGC nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-3-prime
rs566244682 Uncertain significance 140,647,258(+) CACCG(C/T)AGCGG nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-3-prime
rs35672074 Benign 140,647,544(-) CAAAG(C/G/T)TGGGC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon, missense
rs73271536 Benign 140,647,335(+) TTCAG(C/T)TCCAC nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon, utr-variant-3-prime
rs111226907 -- 140,647,839(+) GTGGG(A/C/T)AAGAG downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime

Relevant External Links for MIR3655 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3655

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3655 Gene

Disorders for MIR3655 Gene

Relevant External Links for MIR3655

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3655

No disorders were found for MIR3655 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3655 Gene

Publications for MIR3655 Gene

  1. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
  2. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64
  3. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  4. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4 64
  5. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E. … Sitbon E. (Nucleic Acids Res. 2010) 3 64

Products for MIR3655 Gene

Sources for MIR3655 Gene

Content
Loading form....