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Aliases for MIR3654 Gene

Subcategory (RNA class) for MIR3654 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3654 Gene

  • MicroRNA 3654 2 3 5
  • Hsa-Mir-3654 3

External Ids for MIR3654 Gene

Previous GeneCards Identifiers for MIR3654 Gene

  • GC07U903089
  • GC07M132727
  • GC07M132730
  • GC07M133035
  • GC07M133037
  • GC07M133041
  • GC07M133044

Summaries for MIR3654 Gene

Entrez Gene Summary for MIR3654 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3654 Gene

MIR3654 (MicroRNA 3654) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3654 Gene

Genomics for MIR3654 Gene

Regulatory Elements for MIR3654 Gene

Enhancers for MIR3654 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G133035 0.7 ENCODE 0.7 -0.4 -421 0.2 PKNOX1 MTA2 CEBPB TBX21 TARDBP TCF7 NBN ETV6 MLLT1 IKZF2 MIR3654 PIR56959
GH07G133036 0.6 Ensembl 0.7 -0.8 -786 0.2 PKNOX1 MTA2 CEBPB DPF2 IKZF1 TARDBP TCF7 NBN MLLT1 IKZF2 PIR56959 MIR3654
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3654 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3654 Gene

Chromosome:
7
Start:
133,034,860 bp from pter
End:
133,034,915 bp from pter
Size:
56 bases
Orientation:
Minus strand

Genomic View for MIR3654 Gene

Genes around MIR3654 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3654 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3654 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3654 Gene

ORGUL Member Location for MIR3654 Gene

ORGUL Member Location for MIR3654 gene

Proteins for MIR3654 Gene

Post-translational modifications for MIR3654 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3654 Gene

Domains & Families for MIR3654 Gene

Gene Families for MIR3654 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3654: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3654 Gene

Function for MIR3654 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3654 Gene

Localization for MIR3654 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3654 Gene

Pathways & Interactions for MIR3654 Gene

SuperPathways for MIR3654 Gene

No Data Available

Interacting Proteins for MIR3654 Gene

Gene Ontology (GO) - Biological Process for MIR3654 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3654 Gene

Drugs & Compounds for MIR3654 Gene

No Compound Related Data Available

Transcripts for MIR3654 Gene

mRNA/cDNA for MIR3654 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3654 Gene

No ASD Table

Relevant External Links for MIR3654 Gene

GeneLoc Exon Structure for
MIR3654
ECgene alternative splicing isoforms for
MIR3654

Expression for MIR3654 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3654 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3654 Gene:

MIR3654
genes like me logo Genes that share expression patterns with MIR3654: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3654 Gene

Orthologs for MIR3654 Gene

Evolution for MIR3654 Gene

ENSEMBL:
Gene Tree for MIR3654 (if available)
TreeFam:
Gene Tree for MIR3654 (if available)

No data available for Orthologs for MIR3654 Gene

Paralogs for MIR3654 Gene

(2) SIMAP similar genes for MIR3654 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MIR3654: view

No data available for Paralogs for MIR3654 Gene

Variants for MIR3654 Gene

Sequence variations from dbSNP and Humsavar for MIR3654 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000284492 -- 133,035,871(+) GAGCC(C/T)TGAAG intron-variant, upstream-variant-2KB
rs1001821355 -- 133,034,577(+) GCAGG(G/T)GCAGG intron-variant, downstream-variant-500B
rs1004066417 -- 133,035,214(+) GTGAA(A/C)CCTTC intron-variant, upstream-variant-2KB
rs1006197394 -- 133,036,875(+) AAGCC(A/G)TATAT intron-variant, upstream-variant-2KB
rs1008032241 -- 133,034,394(+) AACTA(C/T)CTAGA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3654 Gene

Variant ID Type Subtype PubMed ID
esv3584599 CNV gain 24956385
nsv1032205 CNV gain 25217958
nsv347 CNV deletion 18451855
nsv825939 CNV gain 20364138
nsv832180 CNV loss 17160897
nsv832182 CNV gain+loss 17160897
nsv975193 CNV duplication 23825009
nsv981582 CNV duplication 23825009

Relevant External Links for MIR3654 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3654

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3654 Gene

Disorders for MIR3654 Gene

Relevant External Links for MIR3654

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3654

No disorders were found for MIR3654 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3654 Gene

Publications for MIR3654 Gene

  1. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  2. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E. … Sitbon E. (Nucleic Acids Res. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3654 Gene

Sources for MIR3654 Gene

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