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Aliases for MIR3653 Gene

Subcategory (RNA class) for MIR3653 Gene

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Quality Score for this RNA gene is

4

Aliases for MIR3653 Gene

  • MicroRNA 3653 2 3 5
  • Hsa-Mir-3653 3
  • Mir-3653 3

External Ids for MIR3653 Gene

Previous GeneCards Identifiers for MIR3653 Gene

  • GC22U900730
  • GC22M029732

Summaries for MIR3653 Gene

Entrez Gene Summary for MIR3653 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3653 Gene

MIR3653 (MicroRNA 3653) is an RNA Gene, and is affiliated with the undefined RNA class.

fRNAdb sequence ontologies for MIR3653 Gene

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

Additional gene information for MIR3653 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3653 Gene

Genomics for MIR3653 Gene

Regulatory Elements for MIR3653 Gene

Enhancers for MIR3653 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22H029336 0.8 ENCODE dbSUPER 0.7 -4.0 -4024 1 HIC1 MAX HNF4A YY1 GAS2L1 MIR3653 LOC102723305
GH22H029341 1.2 ENCODE dbSUPER 0.4 -10.2 -10156 3 ELF3 PKNOX1 FOXA2 NFIB SIN3A KLF17 RAD21 ZNF366 ZSCAN5C FOS RASL10A GAS2L1 ENSG00000237015 RHBDD3 MIR3653 LOC102723305
GH22H029368 1.3 FANTOM5 Ensembl ENCODE 0.3 -36.3 -36270 1 ZNF362 NRF1 HLF CEBPB ZNF266 MAX ZIC2 OSR2 FOSL1 JUND EWSR1 SF3A1 AP1B1 RASL10A SNORD125 TBC1D10A ENSG00000272858 THOC5 NEFH ZNRF3
GH22H029363 1.1 Ensembl ENCODE dbSUPER 0.3 -31.2 -31234 1 HDAC1 SOX6 DPF2 ZEB2 NR2F2 TCF12 IKZF1 NR2C1 IKZF2 SPI1 RASL10A GAS2L1 KREMEN1 MIR3653 LOC102723305
GH22H029381 1.6 Ensembl ENCODE dbSUPER 0.2 -52.1 -52138 8 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF416 ZNF143 RASL10A AP1B1 RPS3AP51 RPL36P17 LOC105372988 SNORD125 ZNRF3 GAS2L1 RHBDD3 LOC102723305
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3653 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3653 Gene

Chromosome:
22
Start:
29,333,158 bp from pter
End:
29,333,267 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR3653 Gene

Genes around MIR3653 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3653 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3653 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3653 Gene

ORGUL Member Location for MIR3653 Gene

ORGUL Member Location for MIR3653 gene

Proteins for MIR3653 Gene

Post-translational modifications for MIR3653 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3653 Gene

Domains & Families for MIR3653 Gene

Gene Families for MIR3653 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3653: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3653 Gene

Function for MIR3653 Gene

Phenotypes From GWAS Catalog for MIR3653 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3653
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3653 Gene

Localization for MIR3653 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3653 Gene

Pathways & Interactions for MIR3653 Gene

SuperPathways for MIR3653 Gene

No Data Available

Interacting Proteins for MIR3653 Gene

Gene Ontology (GO) - Biological Process for MIR3653 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3653 Gene

Drugs & Compounds for MIR3653 Gene

No Compound Related Data Available

Transcripts for MIR3653 Gene

mRNA/cDNA for MIR3653 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3653
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3653 Gene

No ASD Table

Relevant External Links for MIR3653 Gene

GeneLoc Exon Structure for
MIR3653
ECgene alternative splicing isoforms for
MIR3653

Expression for MIR3653 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3653 Gene:

MIR3653
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3653 Gene

Orthologs for MIR3653 Gene

Evolution for MIR3653 Gene

ENSEMBL:
Gene Tree for MIR3653 (if available)
TreeFam:
Gene Tree for MIR3653 (if available)

No data available for Orthologs for MIR3653 Gene

Paralogs for MIR3653 Gene

No data available for Paralogs for MIR3653 Gene

Variants for MIR3653 Gene

Sequence variations from dbSNP and Humsavar for MIR3653 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000132468 -- 29,335,222(+) TCCAC(C/T)AGCGG intron-variant, upstream-variant-2KB
rs1000449335 -- 29,333,866(+) CGAGA(A/C)CAGCC intron-variant, upstream-variant-2KB
rs1000800621 -- 29,333,702(+) AAAAA(C/G)AAAGA intron-variant, upstream-variant-2KB
rs1001127885 -- 29,333,019(+) AGTAA(C/G)TTTGC intron-variant, downstream-variant-500B
rs1001181841 -- 29,333,217(+) ATGAG(C/T)GTGCT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3653 Gene

Variant ID Type Subtype PubMed ID
nsv834171 CNV loss 17160897

Relevant External Links for MIR3653 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3653

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3653 Gene

Disorders for MIR3653 Gene

Relevant External Links for MIR3653

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3653

No disorders were found for MIR3653 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3653 Gene

Publications for MIR3653 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin BM … Amundadottir LT (Nature genetics 2014) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1

Products for MIR3653 Gene

Sources for MIR3653 Gene

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