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Aliases for MIR3653 Gene

Subcategory (RNA class) for MIR3653 Gene


Quality Score for this RNA gene is


Aliases for MIR3653 Gene

  • MicroRNA 3653 2 3 5
  • Hsa-Mir-3653 3
  • Mir-3653 3

External Ids for MIR3653 Gene

Previous GeneCards Identifiers for MIR3653 Gene

  • GC22U900730
  • GC22M029732

Summaries for MIR3653 Gene

Entrez Gene Summary for MIR3653 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3653 Gene

MIR3653 (MicroRNA 3653) is an RNA Gene, and is affiliated with the undefined RNA class.

fRNAdb sequence ontologies for MIR3653 Gene

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3653 Gene

Genomics for MIR3653 Gene

Regulatory Elements for MIR3653 Gene

Enhancers for MIR3653 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G029336 1.1 ENCODE dbSUPER 0.7 -4.0 -4024 1.8 PKNOX1 NFIB YY1 ZNF335 TCF12 CREM TSHZ1 ZNF491 NFIC RAD51 GAS2L1 MIR3653 LOC102723305
GH22G029341 1.2 ENCODE dbSUPER 0.4 -10.2 -10156 3.4 ELF3 PKNOX1 FOXA2 NFIB SIN3A KLF17 RAD21 ZNF366 ZSCAN5C SCRT2 RASL10A GAS2L1 ENSG00000237015 RHBDD3 MIR3653 LOC102723305
GH22G029368 1.3 FANTOM5 Ensembl ENCODE 0.3 -36.3 -36270 1.3 HDGF ZNF266 MAX RBBP5 ZIC2 FOSL1 ZNF121 FOS PRDM10 ZNF263 AP1B1 RASL10A SNORD125 NEFH ZNRF3 CABP7 MIR3653 LOC102723305
GH22G029370 1.3 ENCODE dbSUPER 0.3 -37.5 -37515 0.5 HDGF PKNOX1 ATF1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF48 ZNF2 RASL10A NIPSNAP1 AP1B1 KREMEN1 MIR3653 LOC102723305
GH22G029363 1.2 Ensembl ENCODE dbSUPER 0.3 -31.2 -31234 1.8 HDAC1 MTA2 NR2F1 DPF2 ZEB2 NR2F2 ZNF121 TCF12 ARID1B GATA2 RASL10A GAS2L1 KREMEN1 MIR3653 LOC102723305
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3653 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3653 Gene

29,333,158 bp from pter
29,333,267 bp from pter
110 bases
Minus strand

Genomic View for MIR3653 Gene

Genes around MIR3653 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3653 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3653 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3653 Gene

ORGUL Member Location for MIR3653 Gene

ORGUL Member Location for MIR3653 gene

Proteins for MIR3653 Gene

Post-translational modifications for MIR3653 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3653 Gene

Domains & Families for MIR3653 Gene

Gene Families for MIR3653 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3653: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3653 Gene

Function for MIR3653 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3653 Gene

Localization for MIR3653 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3653 Gene

Pathways & Interactions for MIR3653 Gene

SuperPathways for MIR3653 Gene

No Data Available

Interacting Proteins for MIR3653 Gene

Gene Ontology (GO) - Biological Process for MIR3653 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3653 Gene

Drugs & Compounds for MIR3653 Gene

No Compound Related Data Available

Transcripts for MIR3653 Gene

mRNA/cDNA for MIR3653 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3653 Gene

No ASD Table

Relevant External Links for MIR3653 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3653 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3653 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3653 Gene

Orthologs for MIR3653 Gene

Evolution for MIR3653 Gene

Gene Tree for MIR3653 (if available)
Gene Tree for MIR3653 (if available)

No data available for Orthologs for MIR3653 Gene

Paralogs for MIR3653 Gene

No data available for Paralogs for MIR3653 Gene

Variants for MIR3653 Gene

Sequence variations from dbSNP and Humsavar for MIR3653 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000132468 -- 29,335,222(+) TCCAC(C/T)AGCGG intron-variant, upstream-variant-2KB
rs1000449335 -- 29,333,866(+) CGAGA(A/C)CAGCC intron-variant, upstream-variant-2KB
rs1000800621 -- 29,333,702(+) AAAAA(C/G)AAAGA intron-variant, upstream-variant-2KB
rs1001127885 -- 29,333,019(+) AGTAA(C/G)TTTGC intron-variant, downstream-variant-500B
rs1001181841 -- 29,333,217(+) ATGAG(C/T)GTGCT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3653 Gene

Variant ID Type Subtype PubMed ID
nsv834171 CNV loss 17160897

Relevant External Links for MIR3653 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3653 Gene

Disorders for MIR3653 Gene

Relevant External Links for MIR3653

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR3653 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3653 Gene

Publications for MIR3653 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin B.M. … Amundadottir L.T. (Nat. Genet. 2014) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E. … Sitbon E. (Nucleic Acids Res. 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) . … Gojobori T. (Nucleic Acids Res. 2008) 1

Products for MIR3653 Gene

Sources for MIR3653 Gene

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