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Aliases for MIR3646 Gene

Subcategory (RNA class) for MIR3646 Gene


Quality Score for this RNA gene is


Aliases for MIR3646 Gene

  • MicroRNA 3646 2 3 5
  • Hsa-Mir-3646 3

External Ids for MIR3646 Gene

Previous GeneCards Identifiers for MIR3646 Gene

  • GC20U900618
  • GC20P043038

Summaries for MIR3646 Gene

Entrez Gene Summary for MIR3646 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3646 Gene

MIR3646 (MicroRNA 3646) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3646 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3646 Gene

Genomics for MIR3646 Gene

Regulatory Elements for MIR3646 Gene

Enhancers for MIR3646 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H044397 1.6 Ensembl ENCODE dbSUPER 0.7 +1.1 1135 22.8 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B YBX1 DMAP1 YY1 SRSF6 FITM2 LINC01620 LINC01430 SDC4 HNF4A OSER1-AS1 MIR3646
GH20H044438 1.4 Ensembl ENCODE dbSUPER 0.3 +35.5 35469 10 ELF3 FOXA2 ZBTB40 RAD21 YY1 ZNF121 RCOR1 SMARCC1 CEBPB REST LINC01430 LINC01620 MIR3646
GH20H044421 1.3 ENCODE dbSUPER 0.3 +21.4 21405 15.2 PKNOX1 FOXA2 ATF1 MLX ARID4B DMAP1 YY1 SLC30A9 ZNF143 ATF7 HNF4A SRSF6 LOC105372629 FITM2 LINC01430 LINC01620 PKIG MIR3646
GH20H044450 0.9 ENCODE dbSUPER 0.3 +43.1 43103 0.5 GATAD2A TBP ZNF511 ARID4B HNF4A KDM1A THRB RXRB LINC01620 LINC01430 MIR3646
GH20H044460 1.2 ENCODE dbSUPER 0.2 +53.4 53366 1.3 ELF3 FOXA2 ATF1 ARID4B DNMT3B ZSCAN9 RAD21 RARA RFX5 YY1 FITM2 LINC01620 LINC01430 MIR3646
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3646 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3646 Gene

Genomic Locations for MIR3646 Gene
84 bases
Plus strand

Genomic View for MIR3646 Gene

Genes around MIR3646 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3646 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3646 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3646 Gene

Proteins for MIR3646 Gene

Post-translational modifications for MIR3646 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3646 Gene

Domains & Families for MIR3646 Gene

Gene Families for MIR3646 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3646: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3646 Gene

Function for MIR3646 Gene

Phenotypes From GWAS Catalog for MIR3646 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3646 Gene

Localization for MIR3646 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3646 Gene

Pathways & Interactions for MIR3646 Gene

SuperPathways for MIR3646 Gene

No Data Available

Interacting Proteins for MIR3646 Gene

Gene Ontology (GO) - Biological Process for MIR3646 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3646 Gene

Drugs & Compounds for MIR3646 Gene

No Compound Related Data Available

Transcripts for MIR3646 Gene

mRNA/cDNA for MIR3646 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3646 Gene

No ASD Table

Relevant External Links for MIR3646 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3646 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3646 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3646 Gene:

genes like me logo Genes that share expression patterns with MIR3646: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3646 Gene

Orthologs for MIR3646 Gene

Evolution for MIR3646 Gene

Gene Tree for MIR3646 (if available)
Gene Tree for MIR3646 (if available)

No data available for Orthologs for MIR3646 Gene

Paralogs for MIR3646 Gene

No data available for Paralogs for MIR3646 Gene

Variants for MIR3646 Gene

Sequence variations from dbSNP and Humsavar for MIR3646 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs587777732 Pathogenic 44,406,195(+) TCTTC(C/T)GGAGG upstream-variant-2KB, reference, missense
rs1057517745 Likely pathogenic 44,406,196(+) CTTCC(A/G)GAGGA upstream-variant-2KB, reference, missense
rs193922471 Likely pathogenic 44,407,437(+) CTGCA(C/GG)CTCAA upstream-variant-2KB, reference, frameshift-variant
rs736823 Likely benign 44,406,143(-) CCCGT(A/G)GCCCG upstream-variant-2KB, reference, synonymous-codon
rs371937621 Uncertain significance 44,406,249(+) AATTT(-/T)CTTCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3646 Gene

Variant ID Type Subtype PubMed ID
nsv586065 CNV gain 21841781
nsv1057847 CNV loss 25217958

Relevant External Links for MIR3646 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3646 Gene

Disorders for MIR3646 Gene

Relevant External Links for MIR3646

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR3646 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3646 Gene

Publications for MIR3646 Gene

  1. Identification of microRNAs in Nipple Discharge as Potential Diagnostic Biomarkers for Breast Cancer. (PMID: 25976861) Zhang K … Ma R (Annals of surgical oncology 2015) 3 60
  2. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3646 Gene

Sources for MIR3646 Gene

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