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Aliases for MIR363 Gene

Subcategory (RNA class) for MIR363 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR363 Gene

  • MicroRNA 363 2 3
  • MicroRNA 19b-2 5
  • Hsa-Mir-363 3
  • MIR19B2 5
  • MIR-363 3
  • MIRN363 3

External Ids for MIR363 Gene

Previous HGNC Symbols for MIR363 Gene

  • MIRN363

Previous GeneCards Identifiers for MIR363 Gene

  • GC0XM133150
  • GC0XM133157
  • GC0XM133303

Summaries for MIR363 Gene

Entrez Gene Summary for MIR363 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR363 Gene

MIR363 (MicroRNA 363) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR363 Gene

Genomics for MIR363 Gene

Regulatory Elements for MIR363 Gene

Enhancers for MIR363 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR363 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR363 Gene

Chromosome:
X
Start:
134,168,911 bp from pter
End:
134,174,089 bp from pter
Size:
5,179 bases
Orientation:
Minus strand

Genomic View for MIR363 Gene

Genes around MIR363 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR363 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR363 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR363 Gene

Proteins for MIR363 Gene

Post-translational modifications for MIR363 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR363 Gene

Domains & Families for MIR363 Gene

Gene Families for MIR363 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR363: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR363 Gene

Function for MIR363 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR363 Gene

Localization for MIR363 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR363 Gene

Pathways & Interactions for MIR363 Gene

SuperPathways for MIR363 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR363: view

Pathways by source for MIR363 Gene

1 KEGG pathway for MIR363 Gene

Interacting Proteins for MIR363 Gene

Gene Ontology (GO) - Biological Process for MIR363 Gene

None

No data available for SIGNOR curated interactions for MIR363 Gene

Drugs & Compounds for MIR363 Gene

No Compound Related Data Available

Transcripts for MIR363 Gene

mRNA/cDNA for MIR363 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR363 Gene

No ASD Table

Relevant External Links for MIR363 Gene

GeneLoc Exon Structure for
MIR363
ECgene alternative splicing isoforms for
MIR363

Expression for MIR363 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR363 Gene:

MIR363
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR363 Gene

Orthologs for MIR363 Gene

Evolution for MIR363 Gene

ENSEMBL:
Gene Tree for MIR363 (if available)
TreeFam:
Gene Tree for MIR363 (if available)

No data available for Orthologs for MIR363 Gene

Paralogs for MIR363 Gene

No data available for Paralogs for MIR363 Gene

Variants for MIR363 Gene

Sequence variations from dbSNP and Humsavar for MIR363 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs17251732 -- 134,169,028(+) TGGTG(A/C)TTTAT downstream-variant-500B
rs145836029 -- 134,168,998(+) GGGTA(A/G)TAAAA downstream-variant-500B
rs765431997 -- 134,168,991(+) ATTGT(C/T)AGGGT downstream-variant-500B

Relevant External Links for MIR363 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR363

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR363 Gene

Disorders for MIR363 Gene

Relevant External Links for MIR363

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR363

No disorders were found for MIR363 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR363 Gene

Publications for MIR363 Gene

  1. Downregulation of miR-363 increases drug resistance in cisplatin-treated HepG2 by dysregulating Mcl-1. (PMID: 26143754) Ou Y. … Li X. (Gene 2015) 3 65
  2. REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis. (PMID: 26387746) Kawasaki Y. … Akiyama T. (Sci Rep 2015) 3 65
  3. MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer. (PMID: 26545583) Chapman B.V. … Khan S.A. (BMC Cancer 2015) 3 65
  4. Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis. (PMID: 23975832) Hsu K.W. … Yeh T.S. (Carcinogenesis 2014) 3 65
  5. A novel negative regulator of adipogenesis: microRNA-363. (PMID: 24023010) Chen L. … Liu L. (Stem Cells 2014) 3 65

Products for MIR363 Gene

Sources for MIR363 Gene

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