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Aliases for MIR363 Gene

Subcategory (RNA class) for MIR363 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR363 Gene

  • MicroRNA 363 2 3 5
  • Hsa-Mir-363 3
  • MIR-363 3
  • MIRN363 3

External Ids for MIR363 Gene

Previous HGNC Symbols for MIR363 Gene

  • MIRN363

Previous GeneCards Identifiers for MIR363 Gene

  • GC0XM133150
  • GC0XM133157
  • GC0XM133303
  • GC0XM134170
  • GC0XM134187

Summaries for MIR363 Gene

Entrez Gene Summary for MIR363 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR363 Gene

MIR363 (MicroRNA 363) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Parkinsons Disease Pathway.

Additional gene information for MIR363 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR363 Gene

Genomics for MIR363 Gene

Regulatory Elements for MIR363 Gene

Enhancers for MIR363 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH134148 0.5 FANTOM5 13.1 +20.9 20904 0 CC2D1A RFX1 HINFP ZBTB5 MIR363 GC0XM134143 ENSG00000200572 GC0XM134159
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR363 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR363 Gene

Chromosome:
X
Start:
134,169,378 bp from pter
End:
134,169,452 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR363 Gene

Genes around MIR363 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR363 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR363 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR363 Gene

Proteins for MIR363 Gene

Post-translational modifications for MIR363 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR363 Gene

Domains & Families for MIR363 Gene

Gene Families for MIR363 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR363: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR363 Gene

Function for MIR363 Gene

Gene Ontology (GO) - Molecular Function for MIR363 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20190813
genes like me logo Genes that share ontologies with MIR363: view

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR363
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR363 Gene

Localization for MIR363 Gene

Gene Ontology (GO) - Cellular Components for MIR363 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR363: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR363 Gene

Pathways & Interactions for MIR363 Gene

genes like me logo Genes that share pathways with MIR363: view

Pathways by source for MIR363 Gene

1 BioSystems pathway for MIR363 Gene
1 KEGG pathway for MIR363 Gene

Interacting Proteins for MIR363 Gene

Gene Ontology (GO) - Biological Process for MIR363 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 20190813
genes like me logo Genes that share ontologies with MIR363: view

No data available for SIGNOR curated interactions for MIR363 Gene

Drugs & Compounds for MIR363 Gene

No Compound Related Data Available

Transcripts for MIR363 Gene

mRNA/cDNA for MIR363 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR363
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR363 Gene

No ASD Table

Relevant External Links for MIR363 Gene

GeneLoc Exon Structure for
MIR363
ECgene alternative splicing isoforms for
MIR363

Expression for MIR363 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR363 Gene:

MIR363
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR363 Gene

Orthologs for MIR363 Gene

Evolution for MIR363 Gene

ENSEMBL:
Gene Tree for MIR363 (if available)
TreeFam:
Gene Tree for MIR363 (if available)

No data available for Orthologs for MIR363 Gene

Paralogs for MIR363 Gene

No data available for Paralogs for MIR363 Gene

Variants for MIR363 Gene

Sequence variations from dbSNP and Humsavar for MIR363 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1003224417 -- 134,168,950(+) AGCAC(A/G)TGTAC downstream-variant-500B
rs1003822325 -- 134,171,007(+) AAACC(C/T)TCTCC upstream-variant-2KB
rs1004902717 -- 134,170,953(+) ACCAA(A/G)GTAGG upstream-variant-2KB
rs1005828091 -- 134,169,983(+) ATGTG(G/T)CCTAT downstream-variant-500B, upstream-variant-2KB
rs1007316405 -- 134,171,110(+) ATGGG(A/G)TAACT upstream-variant-2KB

Relevant External Links for MIR363 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR363

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR363 Gene

Disorders for MIR363 Gene

Relevant External Links for MIR363

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR363

No disorders were found for MIR363 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR363 Gene

Publications for MIR363 Gene

  1. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin αv/TGF-β axis. (PMID: 28376277) Pan F … Cai C (Scandinavian journal of immunology 2017) 3 60
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  3. The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer. (PMID: 27420766) Wang SH … Quan ZW (Journal of cellular and molecular medicine 2016) 3 60
  4. miR-363 induces transdifferentiation of human kidney tubular cells to mesenchymal phenotype. (PMID: 26373846) Morizane R … Itoh H (Clinical and experimental nephrology 2016) 3 60
  5. Anti-proliferative Properties of miR-20b and miR-363 from the miR-106a-363 Cluster on Human Carcinoma Cells. (PMID: 27001184) Khuu C … Osmundsen H (MicroRNA (Shariqah, United Arab Emirates) 2016) 3 60

Products for MIR363 Gene

Sources for MIR363 Gene

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