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Aliases for MIR363 Gene

Subcategory (RNA class) for MIR363 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR363 Gene

  • MicroRNA 363 2 3
  • Hsa-Mir-363 3
  • MIR-363 3
  • MIRN363 3

External Ids for MIR363 Gene

ORGUL Members for MIR363 Gene

Previous HGNC Symbols for MIR363 Gene

  • MIRN363

Previous GeneCards Identifiers for MIR363 Gene

  • GC0XM133150
  • GC0XM133157
  • GC0XM133303

Summaries for MIR363 Gene

Entrez Gene Summary for MIR363 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR363 Gene

MIR363 (MicroRNA 363) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR363 Gene

Genomics for MIR363 Gene

Genomic Location for MIR363 Gene

Chromosome:
X
Start:
134,169,361 bp from pter
End:
134,169,473 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for MIR363 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR363 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR363 Gene

No data available for Regulatory Elements for MIR363 Gene

Proteins for MIR363 Gene

Post-translational modifications for MIR363 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR363 Gene

Domains & Families for MIR363 Gene

Gene Families for MIR363 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR363: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR363 Gene

Function for MIR363 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR363 Gene

Localization for MIR363 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR363 Gene

Pathways & Interactions for MIR363 Gene

SuperPathways for MIR363 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR363: view

Pathways by source for MIR363 Gene

1 KEGG pathway for MIR363 Gene

Interacting Proteins for MIR363 Gene

Gene Ontology (GO) - Biological Process for MIR363 Gene

None

No data available for SIGNOR curated interactions for MIR363 Gene

Drugs & Compounds for MIR363 Gene

No Compound Related Data Available

Transcripts for MIR363 Gene

mRNA/cDNA for MIR363 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR363 Gene

No ASD Table

Relevant External Links for MIR363 Gene

GeneLoc Exon Structure for
MIR363
ECgene alternative splicing isoforms for
MIR363

Expression for MIR363 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR363 Gene

Orthologs for MIR363 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR363 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-363 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-363 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-363 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir363 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-363 36
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-363 36
  • 74 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-363 36
  • 46 (a)
OneToOne
Species with no ortholog for MIR363:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR363 Gene

ENSEMBL:
Gene Tree for MIR363 (if available)
TreeFam:
Gene Tree for MIR363 (if available)

Paralogs for MIR363 Gene

No data available for Paralogs for MIR363 Gene

Variants for MIR363 Gene

Sequence variations from dbSNP and Humsavar for MIR363 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs17251732 -- 134,169,028(+) TGGTG(A/C)TTTAT downstream-variant-500B
rs145836029 -- 134,168,998(+) GGGTA(A/G)TAAAA downstream-variant-500B
rs765431997 -- 134,168,991(+) ATTGT(C/T)AGGGT downstream-variant-500B

Relevant External Links for MIR363 Gene

HapMap Linkage Disequilibrium report
MIR363

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR363 Gene

Disorders for MIR363 Gene

Relevant External Links for MIR363

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR363
genes like me logo Genes that share disorders with MIR363: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR363 Gene

Publications for MIR363 Gene

  1. A novel negative regulator of adipogenesis: microRNA-363. (PMID: 24023010) Chen L. … Liu L. (Stem Cells 2014) 67
  2. Dysregulated microRNA expression in adenocarcinoma of the uterine cervix: clinical impact of miR-363-3p. (PMID: 25230213) Park H. … An H.J. (Gynecol. Oncol. 2014) 67
  3. MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytes. (PMID: 24906886) Wagh V. … Bernstein H.S. (Stem Cell Res Ther 2014) 67
  4. Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis. (PMID: 23975832) Hsu K.W. … Yeh T.S. (Carcinogenesis 2014) 67
  5. MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells. (PMID: 24631531) Zhou P. … He F. (Cell. Signal. 2014) 67

Products for MIR363 Gene

Sources for MIR363 Gene

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