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Aliases for MIR3622B Gene

Subcategory (RNA class) for MIR3622B Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3622B Gene

  • MicroRNA 3622b 2 3 5
  • Hsa-Mir-3622b 3

External Ids for MIR3622B Gene

Previous GeneCards Identifiers for MIR3622B Gene

  • GC08U901498
  • GC08M027563

Summaries for MIR3622B Gene

Entrez Gene Summary for MIR3622B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3622B Gene

MIR3622B (MicroRNA 3622b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3622B Gene

Genomics for MIR3622B Gene

Regulatory Elements for MIR3622B Gene

Enhancers for MIR3622B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F027701 0.5 Ensembl ENCODE 0.8 -1.0 -966 2.0 ELF3 SOX13 TBP SAP130 ARID4B DMAP1 THRB ZNF48 ZSCAN9 RARA ENSG00000253875 SCARA3 CLU MIR3622B
GH08F027709 0.2 Ensembl 0.4 -7.9 -7934 0.2 ZIC2 MIR3622B ENSG00000253875
GH08F027727 1.1 Ensembl ENCODE 0.3 -25.5 -25543 0.6 ARID4B DMAP1 ZNF48 YY1 ZNF143 MIER2 REST PPARG KAT8 NFIL3 CCDC25 CLU MIR6843 ESCO2 RNU6-1276P ENSG00000253875 MIR3622B
GH08F027729 0.2 ENCODE 0.3 -28.5 -28528 0.7 KLF1 TAL1 TEAD4 DPF2 ARID1B NCOR1 SMARCA4 KLF16 GABPB1 ZBTB33 CCDC25 CLU MIR6843 RNU6-1276P ESCO2 SCARA3 ENSG00000253875 MIR3622B
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3622B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3622B Gene

Chromosome:
8
Start:
27,701,673 bp from pter
End:
27,701,767 bp from pter
Size:
95 bases
Orientation:
Minus strand

Genomic View for MIR3622B Gene

Genes around MIR3622B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3622B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3622B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3622B Gene

ORGUL Member Location for MIR3622B Gene

ORGUL Member Location for MIR3622B gene

Proteins for MIR3622B Gene

Post-translational modifications for MIR3622B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3622B Gene

Domains & Families for MIR3622B Gene

Gene Families for MIR3622B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3622B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3622B Gene

Function for MIR3622B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3622B Gene

Localization for MIR3622B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3622B Gene

Pathways & Interactions for MIR3622B Gene

SuperPathways for MIR3622B Gene

No Data Available

Interacting Proteins for MIR3622B Gene

Gene Ontology (GO) - Biological Process for MIR3622B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3622B Gene

Transcripts for MIR3622B Gene

mRNA/cDNA for MIR3622B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3622B Gene

No ASD Table

Relevant External Links for MIR3622B Gene

GeneLoc Exon Structure for
MIR3622B
ECgene alternative splicing isoforms for
MIR3622B

Expression for MIR3622B Gene

mRNA expression in normal human tissues for MIR3622B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3622B Gene:

MIR3622B
genes like me logo Genes that share expression patterns with MIR3622B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3622B Gene

Orthologs for MIR3622B Gene

Evolution for MIR3622B Gene

ENSEMBL:
Gene Tree for MIR3622B (if available)
TreeFam:
Gene Tree for MIR3622B (if available)

No data available for Orthologs for MIR3622B Gene

Paralogs for MIR3622B Gene

No data available for Paralogs for MIR3622B Gene

Variants for MIR3622B Gene

Sequence variations from dbSNP and Humsavar for MIR3622B Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs112095039 -- 27,703,504(+) ACTGC(A/G)GCTCC intron-variant, upstream-variant-2KB
rs112756349 -- 27,702,165(+) AGGGC(G/T)CCAGC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs114389054 -- 27,703,722(+) GGAGG(G/T)TTCAT intron-variant, upstream-variant-2KB
rs114459992 -- 27,701,210(+) GTTCT(A/G)GAAAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs114801445 -- 27,702,565(+) GACGC(A/C/G)TCCCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3622B Gene

Variant ID Type Subtype PubMed ID
nsv610867 CNV gain 21841781

Relevant External Links for MIR3622B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3622B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3622B Gene

Disorders for MIR3622B Gene

Relevant External Links for MIR3622B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3622B

No disorders were found for MIR3622B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3622B Gene

Publications for MIR3622B Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3622B Gene

Sources for MIR3622B Gene

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