Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3621 Gene

Subcategory (RNA class) for MIR3621 Gene


Quality Score for this RNA gene is


Aliases for MIR3621 Gene

  • MicroRNA 3621 2 3 5
  • Hsa-Mir-3621 3

External Ids for MIR3621 Gene

Previous GeneCards Identifiers for MIR3621 Gene

  • GC09U901629
  • GC09M140075
  • GC09M140079
  • GC09M140083

Summaries for MIR3621 Gene

Entrez Gene Summary for MIR3621 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3621 Gene

MIR3621 (MicroRNA 3621) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3621 Gene

Genomics for MIR3621 Gene

Regulatory Elements for MIR3621 Gene

Enhancers for MIR3621 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F137168 0.5 ENCODE 0.8 +0.9 907 0.2 HDGF KLF1 KLF17 BCL11B ZIC2 HIC1 ZFHX2 GLIS2 CTBP1 PATZ1 SSNA1 ANAPC2 TPRN GRIN1 MAN1B1 ENSG00000199411 MIR3621 LOC105376328
GH09F137163 0.4 ENCODE 0.4 +6.1 6067 0.2 POLR2A RNF2 L3MBTL2 NRF1 KLF9 KLF8 ANAPC2 SSNA1 TPRN GRIN1 DPP7 MAN1B1 NDOR1 TMEM203 MIR3621 LOC105376328
GH09F137162 0.2 ENCODE 0.4 +6.3 6327 0.2 CTCF RNF2 NRF1 GABPB1 RAD21 EZH2 ANAPC2 SSNA1 TPRN GRIN1 DPP7 MAN1B1 NDOR1 TMEM203 MIR3621 LOC105376328
GH09F137156 0.5 ENCODE 0.4 +12.3 12273 1.2 KLF1 CBX3 ZNF2 ZNF324 ZFHX2 GLIS2 POLR2A PATZ1 PRDM10 KLF7 MAN1B1 ANAPC2 SSNA1 TPRN DPP7 NDOR1 TMEM203 ABCA2 C9orf139 UAP1L1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3621 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3621 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001317935 370 1001 HDGF INSM2 ZNF76 KLF17 SIN3A GLIS2 RCOR1 KLF7 EGR2 ZNF263

Genomic Location for MIR3621 Gene

137,169,186 bp from pter
137,169,270 bp from pter
85 bases
Minus strand

Genomic View for MIR3621 Gene

Genes around MIR3621 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3621 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3621 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3621 Gene

Proteins for MIR3621 Gene

Post-translational modifications for MIR3621 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3621 Gene

Domains & Families for MIR3621 Gene

Gene Families for MIR3621 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3621: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3621 Gene

Function for MIR3621 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3621 Gene

Localization for MIR3621 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3621 Gene

Pathways & Interactions for MIR3621 Gene

SuperPathways for MIR3621 Gene

No Data Available

Interacting Proteins for MIR3621 Gene

Gene Ontology (GO) - Biological Process for MIR3621 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3621 Gene

Transcripts for MIR3621 Gene

mRNA/cDNA for MIR3621 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3621 Gene

No ASD Table

Relevant External Links for MIR3621 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3621 Gene

mRNA expression in normal human tissues for MIR3621 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3621 Gene:

genes like me logo Genes that share expression patterns with MIR3621: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3621 Gene

Orthologs for MIR3621 Gene

Evolution for MIR3621 Gene

Gene Tree for MIR3621 (if available)
Gene Tree for MIR3621 (if available)

No data available for Orthologs for MIR3621 Gene

Paralogs for MIR3621 Gene

No data available for Paralogs for MIR3621 Gene

Variants for MIR3621 Gene

Sequence variations from dbSNP and Humsavar for MIR3621 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs112418895 -- 137,169,404(+) AGTGC(C/T)GCCAG upstream-variant-2KB, reference, synonymous-codon
rs113934942 -- 137,169,412(+) CAGCT(A/C/G)GTTGT upstream-variant-2KB, reference, missense, stop-gained
rs114103459 -- 137,170,993(+) AGGGG(C/T)GGGGG upstream-variant-2KB, reference, synonymous-codon
rs116577970 -- 137,170,847(+) GGGAG(A/G)ACGGT intron-variant, upstream-variant-2KB
rs12000091 -- 137,169,767(+) GAGAG(C/T)GCCGA upstream-variant-2KB, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for MIR3621 Gene

Variant ID Type Subtype PubMed ID
dgv13007n54 CNV loss 21841781
esv2422220 CNV deletion 17116639
esv2761561 CNV gain 21179565
esv3622023 CNV gain 21293372
nsv1161918 CNV duplication 26073780
nsv469918 CNV loss 18288195
nsv524322 CNV loss 19592680
nsv616005 CNV loss 21841781
nsv616007 CNV loss 21841781
nsv951207 CNV deletion 24416366

Relevant External Links for MIR3621 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3621 Gene

Disorders for MIR3621 Gene

Relevant External Links for MIR3621

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR3621 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3621 Gene

Publications for MIR3621 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3621 Gene

Sources for MIR3621 Gene

Loading form....