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Aliases for MIR3621 Gene

Subcategory (RNA class) for MIR3621 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3621 Gene

  • MicroRNA 3621 2 3 5
  • Hsa-Mir-3621 3

External Ids for MIR3621 Gene

Previous GeneCards Identifiers for MIR3621 Gene

  • GC09U901629
  • GC09M140075
  • GC09M140079
  • GC09M140083

Summaries for MIR3621 Gene

Entrez Gene Summary for MIR3621 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3621 Gene

MIR3621 (MicroRNA 3621) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3621 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3621 Gene

Genomics for MIR3621 Gene

GeneHancer (GH) Regulatory Elements for MIR3621 Gene

Promoters and enhancers for MIR3621 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I137166 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 -1.9 -1875 10.1 HDGF SIN3A ZNF2 ZBTB7B GLIS2 ZNF143 KLF7 SP3 REST GMEB1 ENSG00000261793 MIR3621 TMEM210 LRRC26 MAN1B1 TPRN DPH7 INPP5E ARRDC1-AS1 EXD3
GH09I137160 Enhancer 0.9 Ensembl ENCODE 0.4 +5.9 5870 5.3 CTCF KLF1 RAD21 GLIS2 KLF8 CHD2 EZH2 ZNF639 L3MBTL2 NRF1 DPP7 SSNA1 ANAPC2 TPRN GRIN1 MAN1B1 NDOR1 TMEM203 NPDC1 EXD3
GH09I137156 Enhancer 0.8 ENCODE 0.4 +12.3 12272 1.2 KLF1 MZF1 ZNF2 ZNF324 ZFHX2 GLIS2 POLR2A EGR1 PATZ1 VEZF1 LOC105376328 MAN1B1 ANAPC2 SSNA1 TPRN DPP7 NDOR1 TMEM203 ABCA2 C9orf139
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3621 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3621 Gene

Genomic Locations for MIR3621 Gene
chr9:137,169,186-137,169,270
(GRCh38/hg38)
Size:
85 bases
Orientation:
Minus strand
chr9:140,063,638-140,063,722
(GRCh37/hg19)

Genomic View for MIR3621 Gene

Genes around MIR3621 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3621 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3621 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3621 Gene

Proteins for MIR3621 Gene

Post-translational modifications for MIR3621 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3621 Gene

Domains & Families for MIR3621 Gene

Gene Families for MIR3621 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3621: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3621 Gene

Function for MIR3621 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3621 Gene

Localization for MIR3621 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3621 Gene

Pathways & Interactions for MIR3621 Gene

SuperPathways for MIR3621 Gene

No Data Available

Interacting Proteins for MIR3621 Gene

Gene Ontology (GO) - Biological Process for MIR3621 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3621 Gene

Drugs & Compounds for MIR3621 Gene

No Compound Related Data Available

Transcripts for MIR3621 Gene

mRNA/cDNA for MIR3621 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3621 Gene

No ASD Table

Relevant External Links for MIR3621 Gene

GeneLoc Exon Structure for
MIR3621
ECgene alternative splicing isoforms for
MIR3621

Expression for MIR3621 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3621 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3621 Gene:

MIR3621
genes like me logo Genes that share expression patterns with MIR3621: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3621 Gene

Orthologs for MIR3621 Gene

Evolution for MIR3621 Gene

ENSEMBL:
Gene Tree for MIR3621 (if available)
TreeFam:
Gene Tree for MIR3621 (if available)

No data available for Orthologs for MIR3621 Gene

Paralogs for MIR3621 Gene

No data available for Paralogs for MIR3621 Gene

Variants for MIR3621 Gene

Sequence variations from dbSNP and Humsavar for MIR3621 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000093890 -- 137,171,173(-) C/A/G/T upstream_transcript_variant
rs1000146335 -- 137,170,959(-) A/G upstream_transcript_variant
rs1002169460 -- 137,168,707(-) C/G downstream_transcript_variant
rs1003445755 -- 137,169,121(-) G/C downstream_transcript_variant
rs1004061190 -- 137,169,130(-) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3621 Gene

Variant ID Type Subtype PubMed ID
dgv13007n54 CNV loss 21841781
esv2422220 CNV deletion 17116639
esv2761561 CNV gain 21179565
esv3622023 CNV gain 21293372
nsv1161918 CNV duplication 26073780
nsv469918 CNV loss 18288195
nsv524322 CNV loss 19592680
nsv616005 CNV loss 21841781
nsv616007 CNV loss 21841781
nsv951207 CNV deletion 24416366

Additional Variant Information for MIR3621 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3621

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3621 Gene

Disorders for MIR3621 Gene

Additional Disease Information for MIR3621

No disorders were found for MIR3621 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3621 Gene

Publications for MIR3621 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3621 Gene

Sources for MIR3621 Gene

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