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Aliases for MIR3620 Gene

Subcategory (RNA class) for MIR3620 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3620 Gene

  • MicroRNA 3620 2 3 5
  • Hsa-Mir-3620 3
  • Mir-3620 3

External Ids for MIR3620 Gene

Previous GeneCards Identifiers for MIR3620 Gene

  • GC01U903105
  • GC01P228288

Summaries for MIR3620 Gene

Entrez Gene Summary for MIR3620 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3620 Gene

MIR3620 (MicroRNA 3620) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Clathrin derived vesicle budding and Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3620 Gene

Genomics for MIR3620 Gene

Regulatory Elements for MIR3620 Gene

Enhancers for MIR3620 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G228081 1.7 FANTOM5 ENCODE dbSUPER 0.4 -10.7 -10708 10.7 CREB3L1 AGO1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 ZNF610 ZNF585B CICP26 OBSCN ENSG00000269890 C1orf35 WNT3A ENSG00000231563 ENSG00000269934 OBSCN-AS1 ARF1 MIR3620
GH01G228100 1.4 ENCODE dbSUPER 0.4 +5.4 5407 3.7 HDGF PKNOX1 MLX CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 OBSCN C1orf35 OBSCN-AS1 GC01P228103 MIR3620
GH01G228096 0.6 ENCODE 0.7 -1.2 -1156 0.1 ZFHX2 POLR2A ZNF837 GLIS1 ZIC2 ZNF18 EGR2 MIR3620 ARF1
GH01G228092 0.6 dbSUPER 0.7 -4.6 -4559 0.9 ZNF263 AGO1 DPF2 ZNF560 HIC1 ZNF579 POLR2A ZBTB33 IBA57-AS1 HIST3H2A HIST3H2BB RPL23AP15 MIR3620 ARF1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3620 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3620 Gene

Chromosome:
1
Start:
228,097,263 bp from pter
End:
228,097,341 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR3620 Gene

Genes around MIR3620 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3620 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3620 Gene

Proteins for MIR3620 Gene

Post-translational modifications for MIR3620 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3620 Gene

Domains & Families for MIR3620 Gene

Gene Families for MIR3620 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3620: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3620 Gene

Function for MIR3620 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3620 Gene

Localization for MIR3620 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3620 Gene

Pathways & Interactions for MIR3620 Gene

genes like me logo Genes that share pathways with MIR3620: view

Interacting Proteins for MIR3620 Gene

Gene Ontology (GO) - Biological Process for MIR3620 Gene

None

No data available for SIGNOR curated interactions for MIR3620 Gene

Drugs & Compounds for MIR3620 Gene

No Compound Related Data Available

Transcripts for MIR3620 Gene

mRNA/cDNA for MIR3620 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3620 Gene

No ASD Table

Relevant External Links for MIR3620 Gene

GeneLoc Exon Structure for
MIR3620
ECgene alternative splicing isoforms for
MIR3620

Expression for MIR3620 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3620 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3620 Gene:

MIR3620
genes like me logo Genes that share expression patterns with MIR3620: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3620 Gene

Orthologs for MIR3620 Gene

Evolution for MIR3620 Gene

ENSEMBL:
Gene Tree for MIR3620 (if available)
TreeFam:
Gene Tree for MIR3620 (if available)

No data available for Orthologs for MIR3620 Gene

Paralogs for MIR3620 Gene

No data available for Paralogs for MIR3620 Gene

Variants for MIR3620 Gene

Sequence variations from dbSNP and Humsavar for MIR3620 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000058274 -- 228,095,281(+) CTTGG(G/T)GGGGG intron-variant, upstream-variant-2KB
rs1000671194 -- 228,097,498(+) TAGAG(A/G)GGGGG intron-variant, downstream-variant-500B
rs1002341935 -- 228,096,040(+) ACGGG(C/T)GGCCA intron-variant, upstream-variant-2KB
rs1005918915 -- 228,095,866(+) TGGCC(A/G)TCCCC intron-variant, upstream-variant-2KB
rs1006935617 -- 228,096,537(+) CCCCG(A/G)TATTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3620 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv1160102 CNV deletion 26073780
nsv516409 CNV loss 19592680
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv832803 CNV loss 17160897
nsv952136 CNV deletion 24416366

Relevant External Links for MIR3620 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3620

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3620 Gene

Disorders for MIR3620 Gene

Relevant External Links for MIR3620

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3620

No disorders were found for MIR3620 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3620 Gene

Publications for MIR3620 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3620 Gene

Sources for MIR3620 Gene

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