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Aliases for MIR362 Gene

Subcategory (RNA class) for MIR362 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR362 Gene

  • MicroRNA 362 2 3 5
  • Hsa-Mir-362 3
  • Mir-362 3
  • MIRN362 3

External Ids for MIR362 Gene

ORGUL Members for MIR362 Gene

Previous HGNC Symbols for MIR362 Gene

  • MIRN362

Previous GeneCards Identifiers for MIR362 Gene

  • GC0XP049666
  • GC0XP049774
  • GC0XP049778
  • GC0XP049795
  • GC0XP049805
  • GC0XP049833
  • GC0XP050009
  • GC0XP050012
  • GC0XP050017
  • GC0XP050020
  • GC0XP050023

Summaries for MIR362 Gene

Entrez Gene Summary for MIR362 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR362 Gene

MIR362 (MicroRNA 362) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR362 Gene

Genomics for MIR362 Gene

Regulatory Elements for MIR362 Gene

Enhancers for MIR362 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG049976 1.1 Ensembl ENCODE 11.8 -30.6 -30607 3.0 ZFP64 ZNF140 ZNF266 FEZF1 ZNF697 POLR2A ZNF354C PRDM10 ZNF433 TCF7L2 USP27X-AS1 MIR532 MIR188 MIR362 MIR500A MIR500B MIR501 PRAF2 CLCN5 GC0XP049999
GH0XG049957 0.8 Ensembl ENCODE 12.5 -49.3 -49259 3.7 ZNF316 PKNOX1 MAFG NFE2 EMSY SPI1 MIR188 MIR532 MIR362 MIR500A MIR501 MIR500B CLCN5 GC0XM049946 GC0XP049999
GH0XG050034 0.2 ENCODE 13.8 +27.0 26986 2.3 MIR501 MIR500B MIR500A MIR362 MIR188 MIR532 CLCN5 GC0XP050033 PYY3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR362 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR362 Gene

Chromosome:
X
Start:
50,008,964 bp from pter
End:
50,009,028 bp from pter
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR362 Gene

Genes around MIR362 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR362 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR362 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR362 Gene

Proteins for MIR362 Gene

Post-translational modifications for MIR362 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR362 Gene

Domains & Families for MIR362 Gene

Gene Families for MIR362 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR362: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR362 Gene

Function for MIR362 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR362 Gene

Localization for MIR362 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR362 Gene

Pathways & Interactions for MIR362 Gene

SuperPathways for MIR362 Gene

No Data Available

Interacting Proteins for MIR362 Gene

Gene Ontology (GO) - Biological Process for MIR362 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR362 Gene

Transcripts for MIR362 Gene

mRNA/cDNA for MIR362 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR362 Gene

No ASD Table

Relevant External Links for MIR362 Gene

GeneLoc Exon Structure for
MIR362
ECgene alternative splicing isoforms for
MIR362

Expression for MIR362 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR362 Gene:

MIR362
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR362 Gene

Orthologs for MIR362 Gene

Evolution for MIR362 Gene

ENSEMBL:
Gene Tree for MIR362 (if available)
TreeFam:
Gene Tree for MIR362 (if available)

No data available for Orthologs for MIR362 Gene

Paralogs for MIR362 Gene

No data available for Paralogs for MIR362 Gene

Variants for MIR362 Gene

Sequence variations from dbSNP and Humsavar for MIR362 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1004397043 -- 50,009,098(+) TTTGC(C/T)ATGCG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1008396643 -- 50,007,929(+) CGTAG(A/G)TACCA intron-variant, upstream-variant-2KB
rs1008448846 -- 50,008,466(+) TGAGA(G/T)TGCTG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1012297653 -- 50,007,433(+) TCTCT(C/G)TCTCT intron-variant, upstream-variant-2KB
rs1012410619 -- 50,007,206(+) TACTC(A/G)TATAT intron-variant, upstream-variant-2KB

Relevant External Links for MIR362 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR362

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR362 Gene

Disorders for MIR362 Gene

Relevant External Links for MIR362

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR362

No disorders were found for MIR362 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR362 Gene

Publications for MIR362 Gene

  1. MicroRNA-362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1. (PMID: 27878258) Shi C. … Zhang Z. (Oncol. Rep. 2017) 3 64
  2. Downregulation of microRNA-362-3p and microRNA-329 promotes tumor progression in human breast cancer. (PMID: 26337669) Kang H. … Lee E.K. (Cell Death Differ. 2016) 3 64
  3. miR-362-3p targets nemo-like kinase and functions as a tumor suppressor in renal cancer cells. (PMID: 26647877) Zou X. … Tang A. (Mol Med Rep 2016) 3 64
  4. MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45I+. (PMID: 26545365) Yang P. … Wang S.Y. (Mol. Cancer 2015) 3 64
  5. miR-362-5p inhibits proliferation and migration of neuroblastoma cells by targeting phosphatidylinositol 3-kinase-C2I^. (PMID: 26073258) Wu K. … Huang Z. (FEBS Lett. 2015) 3 64

Products for MIR362 Gene

Sources for MIR362 Gene

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