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Aliases for MIR3619 Gene

Subcategory (RNA class) for MIR3619 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3619 Gene

  • MicroRNA 3619 2 3 5
  • Hsa-Mir-3619 3

External Ids for MIR3619 Gene

Previous GeneCards Identifiers for MIR3619 Gene

  • GC22U900743
  • GC22P046489

Summaries for MIR3619 Gene

Entrez Gene Summary for MIR3619 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3619 Gene

MIR3619 (MicroRNA 3619) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3619 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3619 Gene

Genomics for MIR3619 Gene

GeneHancer (GH) Regulatory Elements for MIR3619 Gene

Promoters and enhancers for MIR3619 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I046049 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 -18.3 -18304 45.7 HDGF PKNOX1 FOXA2 SMAD1 ZFP64 SIN3A FEZF1 ZNF2 IRF4 YY1 LOC642648 PRR34 CDPF1 TRMU LINC00899 ATXN10 ENSG00000273243 ENSG00000273287 FAM118A TTC38
GH22I046096 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +12.9 12886 14.9 FOXA2 ARID4B ZNF48 YY1 GLIS2 SP3 RXRA YY2 PPARG KAT8 MIRLET7BHG PPARA PRR34 GC22M046089 MIR3619
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3619 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3619 Gene

Genomic Locations for MIR3619 Gene
chr22:46,091,044-46,091,126
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr22:46,486,924-46,487,006
(GRCh37/hg19)

Genomic View for MIR3619 Gene

Genes around MIR3619 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3619 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3619 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3619 Gene

Proteins for MIR3619 Gene

Post-translational modifications for MIR3619 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3619 Gene

Domains & Families for MIR3619 Gene

Gene Families for MIR3619 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3619: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3619 Gene

Function for MIR3619 Gene

Phenotypes From GWAS Catalog for MIR3619 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3619 Gene

Localization for MIR3619 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3619 Gene

Pathways & Interactions for MIR3619 Gene

SuperPathways for MIR3619 Gene

No Data Available

Interacting Proteins for MIR3619 Gene

Gene Ontology (GO) - Biological Process for MIR3619 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3619 Gene

Drugs & Compounds for MIR3619 Gene

No Compound Related Data Available

Transcripts for MIR3619 Gene

mRNA/cDNA for MIR3619 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3619 Gene

No ASD Table

Relevant External Links for MIR3619 Gene

GeneLoc Exon Structure for
MIR3619
ECgene alternative splicing isoforms for
MIR3619

Expression for MIR3619 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3619 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3619 Gene:

MIR3619
genes like me logo Genes that share expression patterns with MIR3619: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3619 Gene

Orthologs for MIR3619 Gene

Evolution for MIR3619 Gene

ENSEMBL:
Gene Tree for MIR3619 (if available)
TreeFam:
Gene Tree for MIR3619 (if available)

No data available for Orthologs for MIR3619 Gene

Paralogs for MIR3619 Gene

No data available for Paralogs for MIR3619 Gene

Variants for MIR3619 Gene

Sequence variations from dbSNP and Humsavar for MIR3619 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000099401 -- 46,090,602(+) C/T upstream_transcript_variant
rs1000484364 -- 46,089,758(+) C/T upstream_transcript_variant
rs1001099742 -- 46,090,032(+) A/G/T upstream_transcript_variant
rs1001681840 -- 46,089,220(+) C/T upstream_transcript_variant
rs1004213304 -- 46,090,110(+) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3619 Gene

Variant ID Type Subtype PubMed ID
dgv2469n106 OTHER inversion 24896259
dgv776n67 CNV gain 20364138
nsv1152661 OTHER inversion 26484159
nsv459904 CNV loss 19166990
nsv471212 CNV loss 18288195
nsv471213 CNV gain 18288195
nsv516279 CNV loss 19592680
nsv589132 CNV loss 21841781
nsv829281 CNV gain 20364138
nsv829285 CNV gain 20364138

Additional Variant Information for MIR3619 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3619

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3619 Gene

Disorders for MIR3619 Gene

Additional Disease Information for MIR3619

No disorders were found for MIR3619 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3619 Gene

Publications for MIR3619 Gene

  1. miR-3619-5p inhibits prostate cancer cell growth by activating CDKN1A expression. (PMID: 27878260) Li S … Ye Z (Oncology reports 2017) 3 58
  2. Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion. (PMID: 26567912) Fite K … Gomez-Cambronero J (The Journal of biological chemistry 2016) 3 58
  3. Role of MiR-3619-5p in β-Catenin-Mediated Non-Small Cell Lung Cancer Growth and Invasion. (PMID: 26512718) Niu X … Chen J (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015) 3 58
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  5. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 58

Products for MIR3619 Gene

Sources for MIR3619 Gene

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