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Aliases for MIR3618 Gene

Subcategory (RNA class) for MIR3618 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR3618 Gene

  • MicroRNA 3618 2 3 5
  • Hsa-Mir-3618 3

External Ids for MIR3618 Gene

ORGUL Members for MIR3618 Gene

Previous GeneCards Identifiers for MIR3618 Gene

  • GC22U900749
  • GC22P020078

Summaries for MIR3618 Gene

Entrez Gene Summary for MIR3618 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3618 Gene

MIR3618 (MicroRNA 3618) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are mRNA Capping and Gene Expression.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3618 Gene

Genomics for MIR3618 Gene

Regulatory Elements for MIR3618 Gene

Enhancers for MIR3618 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G020078 2 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -4.2 -4225 5.2 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC DGCR8 RPL8P5 TRMT2A RANBP1 ENSG00000243762 ENSG00000273300 SCARF2 MIR185 ZDHHC8 TBX1
GH22G020084 1.3 ENCODE dbSUPER 0.7 -0.8 -824 1.5 HNRNPUL1 HDGF PKNOX1 MLX CREB3L1 ARNT ARID4B SIN3A ZNF2 ZNF143 LINC01311 DGCR8 LOC100420177 SCARF2 ENSG00000273343 RPL7AP70 ZDHHC8 CCDC188 MIR3618
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3618 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3618 Gene

Chromosome:
22
Start:
20,085,746 bp from pter
End:
20,085,833 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR3618 Gene

Genes around MIR3618 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3618 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3618 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3618 Gene

Proteins for MIR3618 Gene

Post-translational modifications for MIR3618 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3618 Gene

Domains & Families for MIR3618 Gene

Gene Families for MIR3618 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3618: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3618 Gene

Function for MIR3618 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3618 Gene

Localization for MIR3618 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3618 Gene

Pathways & Interactions for MIR3618 Gene

genes like me logo Genes that share pathways with MIR3618: view

Pathways by source for MIR3618 Gene

Interacting Proteins for MIR3618 Gene

Gene Ontology (GO) - Biological Process for MIR3618 Gene

None

No data available for SIGNOR curated interactions for MIR3618 Gene

Drugs & Compounds for MIR3618 Gene

No Compound Related Data Available

Transcripts for MIR3618 Gene

mRNA/cDNA for MIR3618 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3618 Gene

No ASD Table

Relevant External Links for MIR3618 Gene

GeneLoc Exon Structure for
MIR3618
ECgene alternative splicing isoforms for
MIR3618

Expression for MIR3618 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3618 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3618 Gene:

MIR3618
genes like me logo Genes that share expression patterns with MIR3618: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3618 Gene

Orthologs for MIR3618 Gene

Evolution for MIR3618 Gene

ENSEMBL:
Gene Tree for MIR3618 (if available)
TreeFam:
Gene Tree for MIR3618 (if available)

No data available for Orthologs for MIR3618 Gene

Paralogs for MIR3618 Gene

No data available for Paralogs for MIR3618 Gene

Variants for MIR3618 Gene

Sequence variations from dbSNP and Humsavar for MIR3618 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000392251 -- 20,084,581(+) TCCGT(A/T)TCTGG intron-variant, upstream-variant-2KB
rs1003220379 -- 20,084,469(+) TCTTC(A/G)TGCTT intron-variant, upstream-variant-2KB
rs1004168121 -- 20,085,400(+) AGTGT(A/G)AATTT intron-variant, upstream-variant-2KB
rs1006072593 -- 20,084,834(+) GTCCC(C/T)GTGCC intron-variant, upstream-variant-2KB
rs1006263947 -- 20,084,032(+) GAAAT(A/G)GGGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3618 Gene

Variant ID Type Subtype PubMed ID
dgv4480n100 CNV gain 25217958
dgv726n67 CNV gain 20364138
dgv7983n54 CNV gain 21841781
esv2758825 CNV loss 17122850
esv3647284 CNV gain 21293372
esv3893434 CNV gain 25118596
nsv471183 CNV loss 18288195
nsv828938 CNV gain 20364138
nsv828939 CNV loss 20364138
nsv834133 CNV loss 17160897
nsv953027 CNV deletion 24416366

Relevant External Links for MIR3618 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3618

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3618 Gene

Disorders for MIR3618 Gene

Relevant External Links for MIR3618

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3618

No disorders were found for MIR3618 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3618 Gene

Publications for MIR3618 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3618 Gene

Sources for MIR3618 Gene

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