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Aliases for MIR3615 Gene

Subcategory (RNA class) for MIR3615 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3615 Gene

  • MicroRNA 3615 2 3 5
  • Hsa-Mir-3615 3
  • Mir-3615 3

External Ids for MIR3615 Gene

Previous GeneCards Identifiers for MIR3615 Gene

  • GC17U901553
  • GC17P072747

Summaries for MIR3615 Gene

Entrez Gene Summary for MIR3615 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3615 Gene

MIR3615 (MicroRNA 3615) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3615 include Nephrolithiasis/Osteoporosis, Hypophosphatemic, 2.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3615 Gene

Genomics for MIR3615 Gene

Regulatory Elements for MIR3615 Gene


Promoters for MIR3615 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000098254 487 2201 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 SLC30A9 SP3 SP5 MXD4

Genomic Location for MIR3615 Gene

Chromosome:
17
Start:
74,748,613 bp from pter
End:
74,748,699 bp from pter
Size:
87 bases
Orientation:
Plus strand

Genomic View for MIR3615 Gene

Genes around MIR3615 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3615 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3615 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3615 Gene

Proteins for MIR3615 Gene

Post-translational modifications for MIR3615 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3615 Gene

Domains & Families for MIR3615 Gene

Gene Families for MIR3615 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3615: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3615 Gene

Function for MIR3615 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3615 Gene

Localization for MIR3615 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3615 Gene

Pathways & Interactions for MIR3615 Gene

SuperPathways for MIR3615 Gene

No Data Available

Interacting Proteins for MIR3615 Gene

Gene Ontology (GO) - Biological Process for MIR3615 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3615 Gene

Drugs & Compounds for MIR3615 Gene

No Compound Related Data Available

Transcripts for MIR3615 Gene

mRNA/cDNA for MIR3615 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3615 Gene

No ASD Table

Relevant External Links for MIR3615 Gene

GeneLoc Exon Structure for
MIR3615
ECgene alternative splicing isoforms for
MIR3615

Expression for MIR3615 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3615 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3615 Gene

This gene is overexpressed in Testis (x22.2), Kidney - Cortex (x11.3), and Small Intestine - Terminal Ileum (x9.6).

NURSA nuclear receptor signaling pathways regulating expression of MIR3615 Gene:

MIR3615
genes like me logo Genes that share expression patterns with MIR3615: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3615 Gene

Orthologs for MIR3615 Gene

Evolution for MIR3615 Gene

ENSEMBL:
Gene Tree for MIR3615 (if available)
TreeFam:
Gene Tree for MIR3615 (if available)

No data available for Orthologs for MIR3615 Gene

Paralogs for MIR3615 Gene

No data available for Paralogs for MIR3615 Gene

Variants for MIR3615 Gene

Sequence variations from dbSNP and Humsavar for MIR3615 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs35910969 Pathogenic 74,749,174(+) AGGAG(C/G)TGCTG downstream-variant-500B, upstream-variant-2KB, reference, missense
rs387907538 Uncertain significance 74,748,879(+) CCCCT(G/T)CCCCG nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon
rs1000511810 -- 74,747,521(+) AGAAG(C/G)CTTTA intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs1001688878 -- 74,747,169(+) GGCCC(C/G)ATAAG nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs1001737054 -- 74,747,611(+) TTACC(C/T)GAGTC intron-variant, downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR3615 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3615

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3615 Gene

Disorders for MIR3615 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3615 Gene - From: GeneCards

Disorder Aliases PubMed IDs
nephrolithiasis/osteoporosis, hypophosphatemic, 2
  • hypophosphatemic nephrolithiasis/osteoporosis 2
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR3615

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3615
genes like me logo Genes that share disorders with MIR3615: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3615 Gene

Publications for MIR3615 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3615 Gene

Sources for MIR3615 Gene

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