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Aliases for MIR3614 Gene

Subcategory (RNA class) for MIR3614 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3614 Gene

  • MicroRNA 3614 2 3 5
  • Hsa-Mir-3614 3
  • Mir-3614 3

External Ids for MIR3614 Gene

Previous GeneCards Identifiers for MIR3614 Gene

  • GC17U901561
  • GC17M054973

Summaries for MIR3614 Gene

Entrez Gene Summary for MIR3614 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3614 Gene

MIR3614 (MicroRNA 3614) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Ovarian tumor domain proteases and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template.

Additional gene information for MIR3614 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3614 Gene

Genomics for MIR3614 Gene

Regulatory Elements for MIR3614 Gene

Enhancers for MIR3614 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H056909 1.7 FANTOM5 ENCODE dbSUPER 0.4 -19.1 -19091 1 PKNOX1 ATF1 ARNT ARID4B YY1 TCF12 ZNF121 ZNF766 GATA2 ATF7 TRIM25 SCPEP1 MIR3614
GH17H056889 0.7 dbSUPER 0.7 +0.2 246 2 GTF2F1 CTCF HLF ZNF133 REST DPF2 ZBTB7B RAD21 ZNF592 ZKSCAN1 TRIM25 C17orf67 SCPEP1 MIR3614 ENSG00000262112
GH17H056907 1 ENCODE dbSUPER 0.4 -17.3 -17291 1 HDGF CTCF PKNOX1 SIN3A MAX EED ATF7 RUNX3 IKZF2 SMARCA5 SCPEP1 TRIM25 MIR3614
GH17H056901 0.9 ENCODE dbSUPER 0.4 -10.9 -10900 1 MXI1 JUN MAX JUND POLR2A HNF4A ZNF600 MYC RNU6-1158P C17orf67 SCPEP1 MIR3614 TRIM25
GH17H056890 0.5 dbSUPER 0.7 +1.8 1805 0 POLR2A HLF CUX1 C17orf67 SCPEP1 MIR3614 ENSG00000262112
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3614 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3614 Gene

Chromosome:
17
Start:
56,891,270 bp from pter
End:
56,891,355 bp from pter
Size:
86 bases
Orientation:
Minus strand

Genomic View for MIR3614 Gene

Genes around MIR3614 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3614 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3614 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3614 Gene

ORGUL Member Location for MIR3614 Gene

ORGUL Member Location for MIR3614 gene

Proteins for MIR3614 Gene

Post-translational modifications for MIR3614 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3614 Gene

Domains & Families for MIR3614 Gene

Gene Families for MIR3614 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3614: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3614 Gene

Function for MIR3614 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3614
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3614 Gene

Localization for MIR3614 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3614 Gene

Pathways & Interactions for MIR3614 Gene

genes like me logo Genes that share pathways with MIR3614: view

Pathways by source for MIR3614 Gene

Interacting Proteins for MIR3614 Gene

Gene Ontology (GO) - Biological Process for MIR3614 Gene

None

No data available for SIGNOR curated interactions for MIR3614 Gene

Drugs & Compounds for MIR3614 Gene

No Compound Related Data Available

Transcripts for MIR3614 Gene

mRNA/cDNA for MIR3614 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3614
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3614 Gene

No ASD Table

Relevant External Links for MIR3614 Gene

GeneLoc Exon Structure for
MIR3614
ECgene alternative splicing isoforms for
MIR3614

Expression for MIR3614 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3614 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3614 Gene

This gene is overexpressed in Whole Blood (x11.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR3614 Gene:

MIR3614
genes like me logo Genes that share expression patterns with MIR3614: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3614 Gene

Orthologs for MIR3614 Gene

Evolution for MIR3614 Gene

ENSEMBL:
Gene Tree for MIR3614 (if available)
TreeFam:
Gene Tree for MIR3614 (if available)

No data available for Orthologs for MIR3614 Gene

Paralogs for MIR3614 Gene

No data available for Paralogs for MIR3614 Gene

Variants for MIR3614 Gene

Sequence variations from dbSNP and Humsavar for MIR3614 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1003393936 -- 56,892,574(+) TCATT(A/G)ATCTA intron-variant, upstream-variant-2KB
rs1003999810 -- 56,893,068(+) GAAGC(C/G)ACGGA intron-variant, upstream-variant-2KB
rs1006012738 -- 56,890,995(+) ACACA(A/G)GCTGA downstream-variant-500B, utr-variant-3-prime
rs1007230759 -- 56,891,441(+) GCCTG(A/G)AGATT upstream-variant-2KB, utr-variant-3-prime
rs1008787737 -- 56,892,874(+) CAACA(C/T)CATGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3614 Gene

Variant ID Type Subtype PubMed ID
esv32884 CNV loss 17666407

Relevant External Links for MIR3614 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3614

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3614 Gene

Disorders for MIR3614 Gene

Relevant External Links for MIR3614

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3614

No disorders were found for MIR3614 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3614 Gene

Publications for MIR3614 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  4. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3614 Gene

Sources for MIR3614 Gene

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