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Aliases for MIR3610 Gene

Subcategory (RNA class) for MIR3610 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3610 Gene

  • MicroRNA 3610 2 3 5
  • Hsa-Mir-3610 3
  • Mir-3610 3

External Ids for MIR3610 Gene

Previous GeneCards Identifiers for MIR3610 Gene

  • GC08U901480
  • GC08M117888

Summaries for MIR3610 Gene

Entrez Gene Summary for MIR3610 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3610 Gene

MIR3610 (MicroRNA 3610) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3610 include Cornelia De Lange Syndrome 4. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Mitotic Metaphase and Anaphase.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3610 Gene

Genomics for MIR3610 Gene

Regulatory Elements for MIR3610 Gene


Promoters for MIR3610 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000229081 800 2801 HDGF PKNOX1 FOXA2 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF766

Genomic Location for MIR3610 Gene

Chromosome:
8
Start:
116,874,728 bp from pter
End:
116,874,800 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR3610 Gene

Genes around MIR3610 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3610 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3610 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3610 Gene

ORGUL Member Location for MIR3610 Gene

ORGUL Member Location for MIR3610 gene

Proteins for MIR3610 Gene

Post-translational modifications for MIR3610 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3610 Gene

Domains & Families for MIR3610 Gene

Gene Families for MIR3610 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3610: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3610 Gene

Function for MIR3610 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3610 Gene

Localization for MIR3610 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3610 Gene

Pathways & Interactions for MIR3610 Gene

genes like me logo Genes that share pathways with MIR3610: view

Pathways by source for MIR3610 Gene

Interacting Proteins for MIR3610 Gene

Gene Ontology (GO) - Biological Process for MIR3610 Gene

None

No data available for SIGNOR curated interactions for MIR3610 Gene

Drugs & Compounds for MIR3610 Gene

No Compound Related Data Available

Transcripts for MIR3610 Gene

mRNA/cDNA for MIR3610 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3610 Gene

No ASD Table

Relevant External Links for MIR3610 Gene

GeneLoc Exon Structure for
MIR3610
ECgene alternative splicing isoforms for
MIR3610

Expression for MIR3610 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3610 Gene:

MIR3610
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3610 Gene

Orthologs for MIR3610 Gene

Evolution for MIR3610 Gene

ENSEMBL:
Gene Tree for MIR3610 (if available)
TreeFam:
Gene Tree for MIR3610 (if available)

No data available for Orthologs for MIR3610 Gene

Paralogs for MIR3610 Gene

No data available for Paralogs for MIR3610 Gene

Variants for MIR3610 Gene

Sequence variations from dbSNP and Humsavar for MIR3610 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001084287 -- 116,874,775(+) ACAAG(A/G)TGGCT nc-transcript-variant, utr-variant-5-prime
rs1001481759 -- 116,874,619(+) GCTCT(C/G)CGCTG nc-transcript-variant, downstream-variant-500B, utr-variant-5-prime
rs1001788776 -- 116,874,790(+) TTACG(C/T)CGCGG nc-transcript-variant, utr-variant-5-prime
rs1003562830 -- 116,875,611(+) AATTT(A/T)TATGG nc-transcript-variant, upstream-variant-2KB
rs1004223902 -- 116,876,585(+) CCCCC(C/G/T)CCAAA nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3610 Gene

Variant ID Type Subtype PubMed ID
nsv1144231 CNV deletion 24896259
nsv6359 CNV insertion 18451855
nsv831434 CNV gain 17160897

Relevant External Links for MIR3610 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3610

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3610 Gene

Disorders for MIR3610 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3610 Gene - From: GeneCards

Disorder Aliases PubMed IDs
cornelia de lange syndrome 4
  • cdls4
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR3610

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3610
genes like me logo Genes that share disorders with MIR3610: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3610 Gene

Publications for MIR3610 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3610 Gene

Sources for MIR3610 Gene

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